Body movement provides a rich source of cues about other people’s goals and intentions. In the present research, we investigate how well people can distinguish between different social intentions on ...the basis of movement information. Participants observed a model reaching toward and grasping a wooden block with the intent to cooperate with a partner, compete against an opponent, or perform an individual action. In Experiment 1, a temporal occlusion procedure was used as to determine whether advance information gained during the viewing of the initial phase of an action allowed the observers to discriminate across movements performed with different intentions. In Experiment 2, we examined what kind of cues observers relied upon for the discrimination of intentions by masking selected spatial areas of the model (i.e., the arm or the face) maintaining the same temporal occlusion as for Experiment 1. Results revealed that observers could readily judge whether the object was grasped with the intent to cooperate, compete, or perform an individual action. Seeing the arm was better than seeing the face for discriminating individual movements performed at different speeds (natural-speed vs. fast-speed individual movements). By contrast, seeing the face was better than seeing the arm for discriminating social from individual movements performed at a comparable speed (cooperative vs. natural-speed individual movements, competitive vs. fast-speed individual movements). These results demonstrate that observers are attuned to advance movement information from different cues and that they can use such kind of information to anticipate the future course of an action.
•Multi-oocyte follicles were observed in 87.5% of sheep ovaries.•The multi-oocyte follicles presented two to five oocytes.•Positive immunostaining for PCNA was observed in 97.2% of the multi-oocytes ...follicles.•Oocytes included multi-oocyte follicles showed a similar pattern of PCNA staining and appeared to be in the same development stage.
The aim of this work was to investigate the cell proliferative activity of multi-oocyte follicles in adult sheep. Ovaries (n=64) were processed for histology and immunostaining with proliferation cell nuclear antigen (PCNA). Multi-oocyte follicles were observed in 87.50% (28/32) pairs of ovaries. Positive immunostaining for anti-PCNA antigen was observed in 97.8% of the one-oocyte follicles and 97.2% of multi-oocytes follicles (p>0.05). Oocytes included in the same follicle showed a similar pattern of PCNA staining and appear to be in the same developmental stage.
We aimed to determine the effectiveness of pneumococcal vaccines on otitis media (OM) and acute otitis media (AOM) in children.
We conducted a systematic search in databases PubMed (MEDLINE), Embase, ...Lilacs, and Web of Science. We included observational studies that evaluated any pneumococcal vaccine – including 7, 10, and 13-valent pneumococcal conjugate vaccines (PCV7, PCV10, and PCV13) and 23-valent polysaccharide vaccines (PPSV23) as the intervention, in children aged less than five years.
Out of the 2112 screened studies, 48 observational studies complied with the eligibility criteria and therefore were included in this review. Of the included studies, 30 (63%) were before-after, eleven (23%) cohort, six (13%) time series, and one (2%) case-control study designs. Vaccine effectiveness (VE) in preventing OM or AOM varied by vaccine type. In children under 24 months VE ranged from 8% and 42.7% (PCV7), 5.6% to 84% (PCV10) and 2.2% to 68% (PCV13). In children aged less than 60 months, VE ranged between 13.2% and 39% for PCV7, 11% to 39% for PCV10 (only children under 48 months), and 39% to 41% (PCV13).
Our results demonstrate significant effect of pneumococcal vaccination in decreasing OM or AOM in children under five years old in several countries supporting the public health value of introducing PCVs in national immunization programs.
According to the kind of opener applied, no-tillage seeders can variously modify soil physical properties in relation to soil and climate conditions, thus potentially affecting crop emergence and ...early growth.
The technological evolution of seeders for direct drilling of arable crops, progressively achieved in recent years, has been considerable, but new improvements now available need to be individually tested. In a field trial at Udine (NE Italy), the effects of a new kind of wide-sweep opener (i.e., side coulters curved upwards in their final part and slightly angled towards the direction of work) on soil physical properties in the seed zone and on crop emergence and early root growth of maize were evaluated in four different soils over a 2-year period (2002–2003), in comparison with the widely used double-disk opener.
With respect to the double-disk opener, in general the wide-sweep type led to higher soil–residue mixing—without excessive reduction of the soil-covering index being observed, −27 and −6%, respectively. The wide-sweep opener also showed lower bulk density and soil penetration resistance in the top 5-cm soil layer of the seed furrow, although no greater root length density was found in maize at the three-leaf stage, probably due to the smoothing effect caused by the side coulters at the seeding depth. A certain delay in plant emergence in some cases was also revealed for the wide-sweep opener, which may be related to the lower soil/seed contact.
Deviations from this general behaviour in the various soils (texture and initial conditions) are discussed.
Semiconductor technologies bring the possibility of embedding billions of components in a chip, allowing the design of complex integrated circuits. However, such levels of integration are not free ...and delay uncertainties grow steadily, which is increasingly challenging. Quasi-delay-insensitive (QDI) design promises to cope with such challenges, being less timing constrained than synchronous or bundled-data designs. However, two barriers to its wider adoption are: 1) missing methods to automatically implement QDI circuits and 2) enabling QDI semi-custom design. This paper proposes a new QDI design method that extends the null convention logic (NCL) asynchronous template. Also, it describes an associated semi-custom design flow for the extended template, which uses conventional electronic design automation tools to synthesize QDI circuits down to layout. The method enables using the full power of synthesis and optimization commercial tools. Illustrating this, the ISCAS85 benchmarks take 35%-43% less gates to implement, compared with conventional, pattern-based NCL design. A comparison with the Uncle tool provides indication that the proposed method is indeed a flexible and powerful approach to design asynchronous QDI circuits. Lastly, 16-b multiplier designed with the method until the layout level exhibits 170%-240% larger operations/Watt compared with an equivalent NCL design, and an almost 400% better operations/mm 2 figure.
The authors describe a VLSI processor for pattern recognition based on content addressable memory (CAM) architecture, optimized for on-line track finding in high-energy physics experiments. A large ...CAM bank stores all trajectories of interest and extracts the ones compatible with a given event. This task is naturally parallelized by a CAM architecture able to output identified trajectories, searching for matches on 96-bit wide patterns, in just a few 40-MHz clock cycles. We have developed this device (called the AMchip03 processor) for the silicon vertex trigger (SVT) upgrade at the Collider Detector experiment at Fermilab (CDF) using a standard-cell VLSI design methodology. This approach provides excellent pattern density, while sparing many of the complexities and risks associated to a full-custom design. The cost/performance ratio is better by well more than one order of magnitude than an FPGA-based design. This processor has a flexible and easily configurable structure that makes it suitable for applications in other experimental environments. They look forward to sharing this technology
The aim of this study was to investigate the effects of alendronate, calcitriol, and calcium in bone loss after kidney transplantation. We enrolled 40 patients (27 men and 13 women, aged 44.2 ± 11.6 ...years) who had received renal allograft at least 6 months before (time since transplant, 61.2 ± 44.6 months). At baseline, parathyroid hormone (PTH) was elevated in 53% of the patients and the Z scores for bone alkaline phosphatase (b‐ALP) and urinary type I collagen cross‐linked N‐telopeptide (u‐NTX) were higher than expected (p < 0.001). T scores for the lumbar spine (−2.4 ± 1.0), total femur (−2.0 ± 0.7), and femoral neck (−2.2 ± 0.6) were reduced (p < 0.001). After the first observation, patients were advised to adhere to a diet containing 980 mg of calcium daily and their clinical, biochemical, and densitometric parameters were reassessed 1 year later. During this period, bone density decreased at the spine (−2.6 ± 5.7%; p < 0.01), total femur (−1.4 ± 4.2%; p < 0.05), and femoral neck (−2.0 ± 3.0%; p < 0.001). Then, the patients were randomized into two groups: (1) group A—10 mg/day of alendronate, 0.50 μg/day of calcitriol, and 500 mg/day of calcium carbonate; and (2) group B—0.50 μg/day of calcitriol and 500 mg/day of calcium carbonate. A further metabolic and densitometric reevaluation was performed after the 12‐month treatment period. At the randomization time, group A and group B patients did not differ as to the main demographic and clinical variables. After treatment, bone turnover markers showed a nonsignificant fall in group B patients, while both b‐ALP and u‐NTX decreased significantly in alendronate‐treated patients. Bone density of the spine (+5.0 ± 4.4%), femoral neck (+4.5 ± 4.9%), and total femur (+3.9 ± 2.8%) increased significantly only in the alendronate‐treated patients. However, no trend toward further bone loss was noticed in calcitriol and calcium only treated subjects. No drug‐related major adverse effect was recorded in the two groups. We conclude that renal transplanted patients continue to loose bone even in the long‐term after the graft. Alendronate normalizes bone turnover and increases bone density. The association of calcitriol to this therapy seems to be advantageous for better controlling the complex abnormalities of skeletal metabolism encountered in these subjects.
An analytical model to simulate the traction performance of mechanical front wheel drive MFWD tractors was developed at the Agroscope Reckenholz-Tänikon ART. The model was validated via several field ...tests in which the relationship between drawbar pull and slip was measured for four MFWD tractors of power ranging between 40 and 123 kW on four arable soils of different texture (clay, clay loam, silty loam, and loamy sand). The pulling tests were carried out in steady-state controlling the pulling force along numerous corridors. Different configurations of tractors were considered by changing the wheel load and the tyre pressure. Simulations of traction performance matched experimental results with good agreement (mean error of 8% with maximum and minimum values of 17% and 1% respectively). The model was used as framework for developing a new module for the excel application TASCV3.0.xlsm, a practical computer tool which compares different tractor configurations, soil textures and conditions, in order to determine variants which make for better traction performance, this resulting in saving fuel and time, i.e. reducing the costs of tillage management.
PDF
