Carbon and nitrogen-doped carbon nanospheres (CNS) were prepared by thermal pyrolysis of benzene (CNSB), aniline (CNSAN), and nitrobenzene (CNSNB) and used as supports for gold nanoparticles. ...Gold-based catalysts were prepared by the gold-sol method. The catalysts were checked in liquid-phase glycerol oxidation. The nature of the N-containing groups influenced both the acid–base properties of the supports and the Au particle deposition. As a consequence, an enhanced metal sintering by enriching the surface electron density of the support, essentially in the quaternary form, was observed. Both the glycerol conversion and glyceric acid selectivity increased with decreasing gold particle size. Moreover, catalyst Au/CNSB promoted the formation of glyceric acid, whereas Au/CNSAN and Au/CNSNB catalysts favored the oxidation of the secondary hydroxyl group of glycerol. Results clearly confirmed the influence of the support properties on the catalytic performance of gold in selective glycerol oxidation.
Abstract We correct an overestimation of the production rate of $$^{137}$$ 137 Xe in the DARWIN detector operated at LNGS. This formerly dominant intrinsic background source is now at a level similar ...to the irreducible background from solar $$^8$$ 8 B neutrinos, thus unproblematic at the LNGS depth. The projected half-life sensitivity for the neutrinoless double beta decay ( $$0\nu \beta \beta $$ 0 ν β β ) of $$^{136}$$ 136 Xe improves by $$22\%$$ 22 % compared to the previously reported number and is now $$T^{0\nu }_{1/2}= {3.0\times 10^{27}} \hbox { yr}$$ T 1 / 2 0 ν = 3.0 × 10 27 yr (90% C.L.) after 10 years of DARWIN operation.
The azimuthal asymmetry in the risetime of signals in Auger surface detector stations is a source of information on shower development. The azimuthal asymmetry is due to a combination of the ...longitudinal evolution of the shower and geometrical effects related to the angles of incidence of the particles into the detectors. The magnitude of the effect depends upon the zenith angle and state of development of the shower and thus provides a novel observable, (sectheta) sub(max), sensitive to the mass composition of cosmic rays above 3x10 super(18)eV. By comparing measurements with predictions from shower simulations, we find for both of our adopted models of hadronic physics (QGSJETII-04 and EPOS-LHC) an indication that the mean cosmic-ray mass increases slowly with energy, as has been inferred from other studies. However, the mass estimates are dependent on the shower model and on the range of distance from the shower core selected. Thus the method has uncovered further deficiencies in our understanding of shower modeling that must be resolved before the mass composition can be inferred from (sectheta) sub(max).
We report new constraints on the size of large extra dimensions from data collected by the MINOS experiment between 2005 and 2012. Our analysis employs a model in which sterile neutrinos arise as ...Kaluza-Klein states in large extra dimensions and thus modify the neutrino oscillation probabilities due to mixing between active and sterile neutrino states. Using Fermilab’s Neutrinos at the Main Injector beam exposure of 10.56×1020 protons on target, we combine muon neutrino charged current and neutral current data sets from the Near and Far Detectors and observe no evidence for deviations from standard three-flavor neutrino oscillations. The ratios of reconstructed energy spectra in the two detectors constrain the size of large extra dimensions to be smaller than 0.45 μm at 90% C.L. in the limit of a vanishing lightest active neutrino mass. Stronger limits are obtained for nonvanishing masses.
We correct an overestimation of the production rate of
137
Xe in the DARWIN detector operated at LNGS. This formerly dominant intrinsic background source is now at a level similar to the irreducible ...background from solar
8
B neutrinos, thus unproblematic at the LNGS depth. The projected half-life sensitivity for the neutrinoless double beta decay (
0
ν
β
β
) of
136
Xe improves by
22
%
compared to the previously reported number and is now
T
1
/
2
0
ν
=
3.0
×
10
27
yr
(90% C.L.) after 10 years of DARWIN operation.
HIV‐1 infection triggers lateral membrane diffusion following interaction of the viral envelope with cell surface receptors. We show that these membrane changes are necessary for infection, as ...initial gp120–CD4 engagement leads to redistribution and clustering of membrane microdomains, enabling subsequent interaction of this complex with HIV‐1 co‐receptors. Disruption of cell membrane rafts by cholesterol depletion before viral exposure inhibits entry by both X4 and R5 strains of HIV‐1, although viral replication in infected cells is unaffected by this treatment. This inhibitory effect is fully reversed by cholesterol replenishment of the cell membrane. These results indicate a general mechanism for HIV‐1 envelope glycoprotein‐mediated fusion by reorganization of membrane microdomains in the target cell, and offer new strategies for preventing HIV‐1 infection.
New variants of SARS-CoV-2 Cantón, Rafael; De Lucas Ramos, Pilar; García-Botella, Alejandra ...
Revista española de quimioterapia,
10/2021, Letnik:
34, Številka:
5
Journal Article
Odprti dostop
The emergence and spread of new variants of SARS-CoV-2 has produced enormous interest due to their possible implication in the improved transmissibility of the virus, their consequences in the ...individual evolution of the infection, as well as in the possible escape from the immunity generated by the current vaccines. The variants that attract most attention are those of public health concern, including B.1.1.7 (UK), P.1 (Brazilian) and B.1.351 (South African). This list is extended by the variants of interest that emerge and are expanding in certain countries but are found sporadically in others, such as B.1.427 and B.1.429 (Californians) or B.1.617 (Indian). Whole genome sequencing or strategies specifically targeting the spicule gene are used in the microbiology laboratories for characterization and detection. The number of infected individuals, the sanitary situation of each country, epidemiological measures and vaccination strategies influence its dispersion and new variants are expected to emerge. This emergence can only be avoided today by increasing the vaccinated population in all countries and by not relaxing epidemiological containment measures. It is not excluded that in the future it will be necessary to revaccinate against new variants.
PDF
