The MiniBooNE experiment at Fermilab reports results from an analysis of ν_{e} appearance data from 12.84×10^{20} protons on target in neutrino mode, an increase of approximately a factor of 2 over ...previously reported results. A ν_{e} charged-current quasielastic event excess of 381.2±85.2 events (4.5σ) is observed in the energy range 200<E_{ν}^{QE}<1250 MeV. Combining these data with the νover ¯_{e} appearance data from 11.27×10^{20} protons on target in antineutrino mode, a total ν_{e} plus νover ¯_{e} charged-current quasielastic event excess of 460.5±99.0 events (4.7σ) is observed. If interpreted in a two-neutrino oscillation model, ν_{μ}→ν_{e}, the best oscillation fit to the excess has a probability of 21.1%, while the background-only fit has a χ^{2} probability of 6×10^{-7} relative to the best fit. The MiniBooNE data are consistent in energy and magnitude with the excess of events reported by the Liquid Scintillator Neutrino Detector (LSND), and the significance of the combined LSND and MiniBooNE excesses is 6.0σ. A two-neutrino oscillation interpretation of the data would require at least four neutrino types and indicate physics beyond the three neutrino paradigm. Although the data are fit with a two-neutrino oscillation model, other models may provide better fits to the data.
The MiniBooNE-DM Collaboration searched for vector-boson mediated production of dark matter using the Fermilab 8-GeV Booster proton beam in a dedicated run with 1.86×10^{20} protons delivered to a ...steel beam dump. The MiniBooNE detector, 490 m downstream, is sensitive to dark matter via elastic scattering with nucleons in the detector mineral oil. Analysis methods developed for previous MiniBooNE scattering results were employed, and several constraining data sets were simultaneously analyzed to minimize systematic errors from neutrino flux and interaction rates. No excess of events over background was observed, leading to a 90% confidence limit on the dark matter cross section parameter, Y=ε^{2}α_{D}(m_{χ}/m_{V})^{4}≲10^{-8}, for α_{D}=0.5 and for dark matter masses of 0.01<m_{χ}<0.3 GeV in a vector portal model of dark matter. This is the best limit from a dedicated proton beam dump search in this mass and coupling range and extends below the mass range of direct dark matter searches. These results demonstrate a novel and powerful approach to dark matter searches with beam dump experiments.
This article deals with multiobjective fractional programming problems with equilibrium constraints in the setting of Hadamard manifolds (abbreviated as MFPPEC). The generalized Guignard constraint ...qualification (abbreviated as GGCQ) for MFPPEC is presented. Furthermore, the Karush–Kuhn–Tucker (abbreviated as KKT) type necessary criteria of Pareto efficiency for MFPPEC are derived using GGCQ. Sufficient criteria of Pareto efficiency for MFPPEC are deduced under some geodesic convexity hypotheses. Subsequently, Mond–Weir and Wolfe type dual models related to MFPPEC are formulated. The weak, strong, and strict converse duality results are derived relating MFPPEC and the respective dual models. Suitable nontrivial examples have been furnished to demonstrate the significance of the results established in this article. The results derived in the article extend and generalize several notable results previously existing in the literature. To the best of our knowledge, optimality conditions and duality for MFPPEC have not yet been studied in the framework of manifolds.
The MiniBooNE Collaboration observes unexplained electronlike events in the reconstructed neutrino energy range from 200 to 475 MeV. With 6.46x10;{20} protons on target, 544 electronlike events are ...observed in this energy range, compared to an expectation of 415.2+/-43.4 events, corresponding to an excess of 128.8+/-20.4+/-38.3 events. The shape of the excess in several kinematic variables is consistent with being due to either nu_{e} and nuover _{e} charged-current scattering or nu_{mu} neutral-current scattering with a photon in the final state. No significant excess of events is observed in the reconstructed neutrino energy range from 475 to 1250 MeV, where 408 events are observed compared to an expectation of 385.9+/-35.7 events.
We report the first measurement of monoenergetic muon neutrino charged current interactions. MiniBooNE has isolated 236 MeV muon neutrino events originating from charged kaon decay at rest ...(K^{+}→μ^{+}ν_{μ}) at the NuMI beamline absorber. These signal ν_{μ}-carbon events are distinguished from primarily pion decay in flight ν_{μ} and νover ¯_{μ} backgrounds produced at the target station and decay pipe using their arrival time and reconstructed muon energy. The significance of the signal observation is at the 3.9σ level. The muon kinetic energy, neutrino-nucleus energy transfer (ω=E_{ν}-E_{μ}), and total cross section for these events are extracted. This result is the first known-energy, weak-interaction-only probe of the nucleus to yield a measurement of ω using neutrinos, a quantity thus far only accessible through electron scattering.
Nanotechnology and biomimicry represent appealing but still underexploited techniques to develop innovative scaffolds with ECM-inspired features for tissue engineering. In the present work we have ...investigated the potential of a combination of two designed elements to trigger enhanced bio-interactions with bone regeneration potential: COOH-functionalized nanodiamond particles (COOH-NDPs) have been loaded for the first time into electrospun fish gelatin hydrogel fibers thus generating nanocomposite fibrous scaffolds with interconnected porosity. When compared to control fish gelatin fibers, no significant modification of the mineralization capacity in acellular simulated body fluid has been evidenced by micro-structural and spectroscopic investigations, for fibers with COOH-NDPs content ranging from 0.25% to 1%. It is important to mention that, following Ca/P alternate incubation, nano-apatite crystals were preferentially developed and firmly adhered on the fiber regions in the proximity of COOH-NDPs, as proven by transmission electron microscopy (TEM). Significant mineralization occurred in the culture media in the presence of MG63 osteoblast-like cells and seems to be directly stimulated by the presence of the nanoparticles. Altogether, these findings emphasize the ability of NDPs to enhance, when immobilized in gelatin fibers and exposed to specific media, the formation of apatite. It was also noticed that the number of adherent MG63 cells, their morphology and spreading were improved by increasing the amount of NDPs in the fibers (fluorescence and scanning electron microscopy). This work successfully proves the potential of such nanocomposite fibers to find applications in bone regeneration.
This work emphasizes the potential of COOH-functionalized nanodiamond (NDs) particles to improve bio-interactions when embedded into fish gelatin electrospun fibers.
In this article, we study nonsmooth interval-valued multiobjective programming problem and generalized Stampacchia vector variational inequality with its weak form for interval-valued functions. ...Using the tools of Mordukhovich subdifferential, we define some new classes of generalized approximate LU-convex functions. These functions are then employed to establish the relations between the solutions of generalized vector variational inequalities and the approximate LU-efficient solutions of the nonsmooth interval-valued multiobjective programming problem. Moreover, we identify the Kuhn-Tucker vector critical points of the considered nonsmooth interval-valued multiobjective programming problem. Under suitable constraint qualification, we establish the equivalence among local approximate LU-efficient points, Kuhn-Tucker vector critical points and the solutions of generalized Stampacchia vector variational inequalities. The results of this paper extend and sharpen the corresponding results of Giannessi F. On Minty variational principle. In: Giannessi F, Komlósi S, Rapcśak T. editors. New trends in mathematical programming. Dordrecht: Kluwer Academic Publishers; 1997. p. 93-99, Golestani M, Sadeghi H, Tavan Y. Nonsmooth multiobjective problems and generalized vector variational inequalities using quasi-efficiency. J Optim Theory Appl. 2018;179(3):896-916, Lee GM, Lee KB. Vector variational inequalities for nondifferentiable convex vector optimization problems. J Global Optim. 2005;32(4):597-612, Mishra SK, Upadhyay BB. Some relations between vector variational inequality problems and nonsmooth vector optimization problems using quasi efficiency. Positivity. 2013;17(4):1071-1083, Upadhyay BB, Mohapatra RN, Mishra SK. On relationships between vector variational inequality and nonsmooth vector optimization problems via strict minimizers. Adv Nonlinear Var Inequal. 2017;20(2):1-12, Zhang J, Zheng Q,Ma X, Li L. Relationships between interval-valued vector optimization problems and vector variational inequalities. Fuzzy Optim Decis Mak. 2016;15(1):33-55 for nonsmooth interval-valued multiobjective programming problem by using the powerful tool of Mordukhovich subdifferential.
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