ABSTRACT
In this paper, we report the discovery of TOI-220 b, a new sub-Neptune detected by the Transiting Exoplanet Survey Satellite (TESS) and confirmed by radial velocity follow-up observations ...with the HARPS spectrograph. Based on the combined analysis of TESS transit photometry and high precision radial velocity measurements, we estimate a planetary mass of 13.8 ± 1.0 M⊕ and radius of 3.03 ± 0.15 R⊕, implying a bulk density of 2.73 ± 0.47 $\rm {g\,cm}^{-3}$. TOI-220 b orbits a relative bright (V= 10.4) and old (10.1 ± 1.4 Gyr) K dwarf star with a period of ∼10.69 d. Thus, TOI-220 b is a new warm sub-Neptune with very precise mass and radius determinations. A Bayesian analysis of the TOI-220 b internal structure indicates that due to the strong irradiation it receives, the low density of this planet could be explained with a steam atmosphere in radiative–convective equilibrium and a supercritical water layer on top of a differentiated interior made of a silicate mantle and a small iron core.
Cows’ milk containing elevated concentrations of Se provides a rich nutritional source of this essential element for meeting daily nutritional requirements or providing health benefits in humans with ...low immune function or at risk of cancer. An experiment involving either 2 or 6 wk of dietary supplementation with Se yeast (with the yeast supplying about 30, 40, and 60mg of Se/d for cows supplemented for 2 wk, and about 20, 30, 40, and 60mg of Se/d for cows supplemented for 6 wk), and 21 wk of monitoring of Se status after the withdrawal of supplementation, was undertaken between September 2008 and April 2009 using 35 multiparous Holstein-Friesian cows. Using milk and blood Se concentrations as surrogates, the research examined the time taken for Se build-up in tissue due to supplementation of lactating dairy cows with Se yeast to dissipate back to normal levels. At the end of Se supplementation, a significant relationship was found between milk Se concentration and Se intake, whereby milk Se concentration had increased by 4.5μg of Se/kg of milk for each mg of Se eaten per day, but no effect of duration of supplementation on this relationship was observed. At the same time, both Se intake and duration of supplementation affected blood Se concentration; it increased by 3.6μg of Se/kg of blood for each mg of Se eaten per day, and was 86μg of Se/kg higher after 6 wk compared with 2 wk of supplementation. After the withdrawal of Se supplementation, milk Se concentrations responded quickly to the change in the quantity of Se consumed, and again, duration of supplementation had no effect on the response, but any effect that Se intake had on milk Se had completely dissipated by 4 wk. In contrast to milk, blood Se concentrations continued to be affected by both amount and duration of Se supplementation for at least 4 mo after the withdrawal of supplementation, although by 5 mo the effects of the previous supplementation treatments had virtually disappeared. The slow decline in blood Se concentrations after the withdrawal of supplementation would most likely be due to the protracted clearance of Se from the various tissues that had accumulated Se during supplementation and the rate of erythrocyte turnover. When undertaking an on-farm Se enhancement program to generate milk for the manufacture of Se-enriched milk products, post-supplementation milk Se concentrations are unlikely to create any problems at the milk factory beyond 4 wk, but the high residual blood/tissue Se concentrations that take considerably more time to dissipate may provide the potential for possible unintended consequences at the food chain/farm environment level.
Observations spanning a large wavelength range, from X-ray to radio, of the Type IIb supernova (SN) 2011hs are presented, covering its evolution during the first year after explosion. The optical ...light curve presents a narrower shape and a fainter luminosity at peak than previously observed for Type IIb SNe. High expansion velocities are measured from the broad absorption H i and He i lines. From the comparison of the bolometric light curve and the time evolution of the photospheric velocities with hydrodynamical models, we found that SN 2011hs is consistent with the explosion of a 3-4 M He-core progenitor star, corresponding to a main-sequence mass of 12-15 M, that ejected a mass of 56Ni of about 0.04 M, with an energy of E = 8.5 × 1050 ERG. Such a low-mass progenitor scenario is in full agreement with the modelling of the nebular spectrum taken at ∼215 d from maximum. From the modelling of the adiabatic cooling phase, we infer a progenitor radius of 500-600 R, clearly pointing to an extended progenitor star. The radio light curve of SN 2011hs yields a peak luminosity similar to that of SN 1993J, but with a higher mass-loss rate and a wind density possibly more similar to that of SN 2001ig. Although no significant deviations from a smooth decline have been found in the radio light curves, we cannot rule out the presence of a binary companion star.
Objective:
The failure of offenders to complete psychological treatment can pose significant concerns, including increased risk for recidivism. Although a large literature identifying predictors of ...offender treatment attrition has accumulated, there has yet to be a comprehensive quantitative review.
Method:
A meta-analysis of the offender treatment literature was conducted to identify predictors of offender treatment attrition and examine its relationship to recidivism. The review covered 114 studies representing 41,438 offenders. Sex offender and domestic violence programs were also examined separately given their large independent literatures.
Results:
The overall attrition rate was 27.1% across all programs (
k
= 96), 27.6% from sex offender programs (
k
= 34), and 37.8% from domestic violence programs (
k
= 35). Rates increased when preprogram attrition was considered. Significant predictors included demographic characteristics (e.g., age,
r
w
= −.10), criminal history and personality variables (e.g., prior offenses,
r
w
= .14; antisocial personality,
r
w
= .14), psychological concerns (e.g., intelligence,
r
w
= −.14), risk assessment measures (e.g., Statistical Information on Recidivism scale,
r
w
=.18), and treatment-related attitudes and behaviors (e.g., motivation,
r
w
= −.13). Results indicated that treatment noncompleters were higher risk offenders and attrition from all programs significantly predicted several recidivism outcomes ranging from
r
w
= .08 to .23.
Conclusions:
The clients who stand to benefit the most from treatment (i.e., high-risk, high-needs) are the least likely to complete it. Offender treatment attrition can be managed and clients can be retained through an awareness of, and attention to, key predictors of attrition and adherence to responsivity considerations.
We present the UV, optical, X-ray, and radio properties of the Type IIb SN 2008ax discovered in NGC 4490. The observations in the UV are one of the earliest of a Type IIb supernova (SN). On ...approximately day 4 after the explosion, a dramatic upturn in the u and uvw1 (lambda{sub c} = 2600 A) light curves occurred after an initial rapid decline which is attributed to adiabatic cooling after the initial shock breakout. This rapid decline and upturn is reminiscent of the Type IIb SN 1993J on day 6 after the explosion. Optical/near-IR spectra taken around the peak reveal prominent Halpha, He I, and Ca II absorption lines. A fading X-ray source is also located at the position of SN 2008ax, implying an interaction of the SN shock with the surrounding circumstellar material and a mass-loss rate of the progenitor of M-dot=(9+-3)x10{sup -6}M{sub odot}yr{sup -1}. The unusual time evolution (14 days) of the 6 cm peak radio luminosity provides further evidence that the mass-loss rate is low. Combining the UV, optical, X-ray, and radio data with models of helium exploding stars implies the progenitor of SN 2008ax was an unmixed star in an interacting binary. Modeling of the SN light curve suggests a kinetic energy (E{sub k} ) of 0.5 x 10{sup 51} erg, an ejecta mass (M {sub ej}) of 2.9 M {sub sun}, and a nickel mass (M {sub Ni}) of 0.06 M {sub sun}.
Summary Objective To test the hypothesis that the spondyloepiphyseal dysplasia congenita ( sedc ) heterozygous ( sedc /+) mouse, a COL2A1 mutant, is a model for the study of osteoarthritis (OA) in ...the absence of dwarfism and to investigate the presence of HtrA1, Ddr2, and Mmp-13 and their possible involvement in a universal mechanism leading to OA. Design Whole mount skeletons of adult animals were analyzed to determine whether sedc /+ mice exhibit dwarfism. To characterize progression of osteoarthritic degeneration over time, knee and temporomandibular joints from sedc /+ and wild-type mice were analyzed histologically, and severity of articular cartilage degradation was graded using the Osteoarthritis Research Society International (OARSI) scoring system. Immunohistochemistry was used to detect changes in expression of HtrA1, Ddr2, and Mmp-13 in articular cartilage of knees. Results As previously reported, the sedc /+ skeleton morphology was indistinguishable from wild type, and skeletal measurements revealed no significant differences. The sedc /+ mouse did, however, show significantly higher OARSI scores in knee (9, 12 and 18 months) and temporomandibular joints at all ages examined. Histological staining showed regions of proteoglycan degradation as early as 2 months in both temporomandibular and knee joints of the mutant. Cartilage fissuring and erosion were observed to begin between 2 and 6 months in temporomandibular joints and 9 months in knee joints from sedc /+ mice. Immunohistochemistry of mutant knee articular cartilage showed increased expression of HtrA1, Ddr2, and Mmp-13 compared to wild type, which upregulation preceded fibrillation and fissuring of the articular surfaces. Conclusions With regard to skeletal morphology, the sedc /+ mouse appears phenotypically normal but develops premature OA as hypothesized. We conclude that the sedc /+ mouse is a useful model for the study of OA in individuals with overtly normal skeletal structure and a predisposition for articular cartilage degeneration.
Fifteen rumen fistulated Holstein cows in late lactation and fed a total mixed ration offered ad libitum were supplemented with Se yeast to provide 0, 11, 20, 30, or 42mg of supplemental Se/day to ...test the hypothesis that amounts of Se secreted in milk, excreted in urine and feces, and apparently retained in tissues would increase in direct proportion to Se intake. One-half of the yeast supplement was placed directly into the rumen through the fistula of each cow just before milking in the morning and again in the evening, and estimates of average daily excretion of Se were made using total collections of urine and feces from 25 to 31 d after treatments commenced. Amounts of Se secreted daily in milk and apparently retained in tissues increased linearly with average daily intake of Se. The amount of Se excreted in feces and total excretion of Se in urine plus feces increased curvilinearly with Se intake, such that proportionately less Se was excreted as the amount of Se fed increased. On average, total Se excretion accounted for 66%, Se secretion in milk accounted for 17%, and Se apparently retained in tissues accounted for 17% of total Se intake by cows. Thus, in herds fed large amounts of Se yeast, most of the Se will be excreted and retained on-farm. High concentrations of Se will be found where urine and feces accumulate (e.g., yards and effluent ponds), and effluent management practices must be tailored to avoid environmental issues.
Sixteen cows in mid-lactation (milk yield of 23.8±2.3 kg/d) were individually fed diets consisting of chopped perennial ryegrass hay, offered at 3kg of dry matter (DM)/100kg of body weight (BW), fed ...either alone or supplemented with amounts of crushed wheat ranging from 0.4 to 1.6kg of DM/100kg of BW (increasing at nominal intervals of 0.4kg of DM/100kg of BW; 5 nominal treatments in total). Three cows were allocated to each treatment except the mid-range wheat treatment, which had 4 cows. Results were analyzed by regression because the intake of the wheat by cows within treatments varied. The hay was used to reflect the characteristics of summer pastures in southeastern Australia. Feed intake and fecal output were measured to determine digestion coefficients, feeds were incubated in nylon bags in the rumen, and rumen variables were monitored. Estimates of metabolizable energy (ME) of the hay from in vivo or in vitro digestibility were also compared. The digestibility of neutral detergent fiber (NDF) was depressed linearly as the amount of crushed wheat consumed increased to 36% of DM intake. The extent to which negative associative effects on NDF digestion were associated with the hay could not be determined, as it was not possible to distinguish between the NDF from hay and that from wheat. However, acid detergent fiber (ADF) digestion also declined, suggesting that most of the response lay with the hay because ADF was negligible in the wheat. Most data indicated that effects of proportion of wheat in the diet on the utilization of consumed nutrients were small. Despite substitution of wheat for hay reducing the forage intake of cows, there was a positive linear effect on marginal milk responses (1.3kg of energy-corrected milk/kg of DM wheat). Mean rumen fluid pH declined as the proportion of wheat in the diet increased. The lowest pH for any individual cow during a 24-h period was 5.4, and the amount of time that rumen fluid pH was <6.0 ranged from 0 to 14h depending on the amount of wheat consumed. It was concluded that these perturbations of the rumen environment were probably sufficient to result in negative associative effects. In addition, estimates of the ME content of the hay were higher when calculated from in vitro compared with in vivo digestibility, which has implications when estimating the amount of feed required for production.
Airborne measurements within the urban mixing layer (360 m) over Greater London are used to quantify CO2 emissions at the meso-scale. Daytime CO2 fluxes, calculated by the Integrative Mass Boundary ...Layer (IMBL) method, ranged from 46 to 104 μmol CO2m−2s−1 for four days in October 2011. The day-to-day variability of IMBL fluxes is at the same order of magnitude as for surface eddy-covariance fluxes observed in central London. Compared to fluxes derived from emissions inventory, the IMBL method gives both lower (by −37%) and higher (by 19%) estimates. The sources of uncertainty of applying the IMBL method in urban areas are discussed and guidance for future studies is given.
•CO2 was measured by aircraft in London within the urban mixing layer (360 m).•Meso-scale urban emissions were estimated using aircraft observations.•Airborne-fluxes within −37% and 20% of emissions from inventory.•Airborne-fluxes within the range of eddy-covariance observations in central London.
CO2 airborne-derived fluxes by Boundary Layer Mass balance are an independent measure of meso-scale urban fluxes complementing urban eddy-covariance fluxes and emissions inventory.
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