Es importante estandarizar los procesos de ingreso a las UCI (UCI), y las prácticas establecidas por consenso determinan intervenciones de calidad que pueden potenciar contextos específicos. Las UCI ...son servicios finitos de alto costo que requieren políticas para garantizar el uso racional y poder brindar atención de calidad a los pacientes. En respuesta a la variabilidad de los criterios de ingreso a la UCI en el país, la Asociación Colombiana de Medicina Crítica y Cuidados Intensivos (AMCI) convocó un equipo multidisciplinario de expertos en medicina crítica para establecer un pronunciamiento científico mediante la metodología de consenso formal, principalmente por el método Delphi, acerca de las recomendaciones y prácticas que permitan homogenizar los criterios de ingreso a las UCI en Colombia. Como parte de la misión de la AMCI, se pretende impactar positivamente en los distintos niveles del sistema de salud (prestadores, administradores, aseguradores y gobierno) y que al final se refleje en beneficios para los pacientes críticos o en riesgo. El consenso invita a todas las UCI del país a seleccionar sus propios criterios teniendo en cuenta el listado de las recomendaciones que contiene; se aclara que los contenidos son generados en un contexto científico, académico y no comercial. Cada institución de salud debe ser garante, mediante la coordinación asistencial de las UCI, del uso responsable de estos criterios tanto para la atención segura y de calidad de los pacientes como de utilizarlos para las distintas relaciones comerciales que se establezcan con las administradoras de los regímenes de salud. Este documento tiene un alcance nacional y su contenido está previsto actualizarlo en un tiempo no mayor a 4años.
It is important to standardize the admission processes to the Intensive Care Units (ICU), and the practices established by consensus determine quality interventions that can enhance specific contexts. ICU are finite, high-cost services that require policies to ensure rational use and to provide quality care to patients. In response to the variability of ICU admission criteria in the country, the Colombian Association of Critical Medicine and Intensive Care (AMCI) convened a multidisciplinary team of experts in critical medicine to establish a scientific statement using the formal consensus methodology, mainly by the Delphi method, about the recommendations and practices that allow to homogenize the criteria for admission to ICU in Colombia. As part of the mission of the AMCI, it is intended to have a positive impact on the different levels of the health system — providers, administrators, insurers and government — and that in the end it will be reflected in benefits for critically ill or at-risk patients. The consensus invites all ICU in the country to select their own criteria taking into account the list of recommendations it contains; it is clarified that the contents are generated in a scientific, academic and non-commercial context. Each health institution must be a guarantor, through the care coordination of the ICUs, of the responsible use of these criteria both for the safe and quality care of patients and to use them for the different commercial relationships established with the administrators of the regimens of health. This document has a national scope and its content is expected to be updated in no more than 4years.
La pandemia de COVID-19 ha generado múltiples interrogantes respecto a su comportamiento en la población gestante y en los resultados perinatales. Los datos disponibles sobre la infección por ...SARS-CoV-2 en el embarazo son limitados. Se realizó una búsqueda de artículos publicados en las bases de datos PubMed, Scopus y Embase utilizando los términos asociados a COVID-19 y embarazo, hasta el 4 de abril de 2020. En la revisión de 43 artículos se tuvieron en cuenta 25, que corresponden a reportes y series de caso, revisiones y guías de manejo. No se encontró evidencia concluyente respecto a transmisión vertical o a mal resultado perinatal en enfermedad leve o moderada. Los síntomas clínicos de COVID-19 en el embarazo, no varían de los de la población general. Existe controversia en cuanto a lactancia materna. En conclusión, existe escasa evidencia de calidad sobre el efecto de COVID-19 en el embarazo. Dada la ausencia de evidencia concluyente se plantea la realización de un registro nacional de COVID-19 y embarazo para Colombia y la región.
Exogenous nucleotides (NT) have been reported to exert a reparative role in animal models of intestinal and hepatic damage. Thus, the administration of NT in the diet of rats with ...thioacetamide-induced liver cirrhosis normalized many of the histological and biochemical alterations produced by this hepatotoxin. We are currently studying the mechanism by which NT exert this effect using cell culture models. The aim of this work was to investigate whether exogenous nucleosides (NS) modulate the proliferation of hepatocytes. We used fetal rat hepatocytes, which, unlike adult hepatocytes, are proliferative cells. Fetal rat primary hepatocytes were incubated with mixtures of NS, and cell proliferation was studied. NS added to the medium of fetal hepatocytes were taken up in a selective fashion by the cells. Cell proliferation was enhanced, as demonstrated by the induction of c-myc and h-ras gene expression as well as by the higher percentage of cells in S phase, and exogenous NS increased the expression of α-fetoprotein. These results suggest that exogenous NS may in fact stimulate proliferation of hepatic cells and help preserve the undifferentiated state of fetal rat hepatocytes.
The present manuscript consists in a deep revision on the quantitative and qualitative studies related to the effectiveness of the corners in football. We have consulted five of the most ...internationally recognized databases, Google Scholar, PubMed, SPORTDiscus, Scopus and Web of Science. The criterion for the selection of the descriptors and the search period was aimed at accessing the main empirical works that included corner kicks. The main objective is to reach a deeper knowledge (and with the adequate empirical support) of the corner kicks in soccer. The results have been classified into three sections: 1) On a descriptive level, to know the regularity, influence and incidence of these actions in current football; 2) know the statistically significant variables associated with success in this type of actions; 3) Finally, to know and analyze the studies that collect different explanatory models (multivariate analysis). Finally, practical guidelines derived from the results of the reviewed research that can contribute to the optimization of this type of actions in professional football are presented.
The present manuscript consists in a deep revision on the quantitative and qualitative studies related to the effectiveness of the corners in football. We have consulted five of the most ...internationally recognized databases, Google Scholar, PubMed, SPORTDiscus, Scopus and Web of Science. The criterion for the selection of the descriptors and the search period was aimed at accessing the main empirical works that included corner kicks. The main objective is to reach a deeper knowledge (and with the adequate empirical support) of the corner kicks in soccer. The results have been classified into three sections: 1) On a descriptive level, to know the regularity, influence and incidence of these actions in current football; 2) know the statistically significant variables associated with success in this type of actions; 3) Finally, to know and analyze the studies that collect different explanatory models (multivariate analysis). Finally, practical guidelines derived from the results of the reviewed research that can contribute to the optimization of this type of actions in professional football are presented.
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