Personalized mobile healthcare integrated with various wearable devices has become a significant area of interest in the present era. In the current research work, a flexible, wearable and disposable ...paper-based continuous skin temperature monitoring sensor for early medical prognosis and accurate diagnosis of body temperature-related ailments, such as COVID-19, is proposed. Conventional screen-printing and drop-casting techniques were used to fabricate the proposed sensor using MWCNTs as the sensing material and paper as the substrate. The linearity, stability, repeatability and durability of the sensors were tested from 29°C (room temperature) to 60°C. A thin sheet of PET was laminated over the sensor surface to ascertain its stability toward environmental effects and physical movements, and a response time of ~13 s and a recovery time of ~38 s with a sensitivity of −0.0685% °C −1 were recorded. The efficacy of the proposed sensor was ascertained by placing it at different body locations on a human subject and comparing it with a standard thermocouple and IR sensor. The sensor even helped to effectively distinguish minimal temperature variations between various regions of the body. Furthermore, the feasibility of the fabricated temperature sensor as a temperature-based tactile sensor for robotics/artificial skin applications and as a noncontact breath monitoring device for use in personalized healthcare monitoring applications was investigated.
Accurate measurement and monitoring of respiration is vital in patients affected by severe acute respiratory syndrome coronavirus - 2 (SARS-CoV-2). Patients with severe chronic diseases and pneumonia ...need continuous respiration monitoring and oxygenation support. Existing respiratory sensing techniques require direct contact with the human body along with expensive and heavy Holter monitors for continuous real-time monitoring. In this work, we propose a low-cost, non-invasive and reliable paper-based wearable screen printed sensor for human respiration monitoring as an effective alternative of existing sensing systems. The proposed sensor was fabricated using traditional screen printing of multi-walled carbon nanotubes (MWCNTs) and polydimethylsiloxane (PDMS) composite based interdigitated electrodes on paper substrate. The paper substrate was used as humidity sensing material of the sensor. The hygroscopic nature of paper during inhalation and exhalation causes a change in dielectric constant, which in turn changes the capacitance of the sensor. The composite interdigitated electrode configuration exhibited better response times with a rise time of 1.178s being recorded during exhalation and fall time of 0.88s during inhalation periods. The respiration rate of sensor was successfully examined under various breathing conditions such as normal breathing, deep breathing, workout, oral breathing, nasal breathing, fast breathing and slow breathing by employing it in a wearable mask, a mandatory wearable product during the current COVID-19 pandemic situation.Thus, the above proposed sensor may hold tremendous potential in wearable/flexible healthcare technology with good sensitivity, stability, biodegradability and flexibility at this time of need.
In this study, Kaolin clay, a mining material, was used as an abundant and available mineral as zero-valent iron-kaolinite composites for As2O3 removal from the water samples. The composites were ...made by the sodium borohydrate reduction method. The existence of Fe0 in the produced composites was confirmed by X-ray diffraction (XRD) and Fourier-Transform Infrared Spectroscopy (FTIR) analysis. The membranes are prepared with zerovalent nano Iron–Kaolin and PES. The synthesized composites were then mixed with polyethersulfone to prepare the membranes S1, S2, and S3 with varying compositions. Field Emission Scanning Electron Microscopy (FESEM) analysis of the produced membranes showed the porous structure and the contact angle of membranes increased the hydrophilicity. The membranes were explored for the removal of As2O3 (AsIII) in potable water samples. The filtration studies were carried out using the syringe filtration setup. Analysis of the arsenic (III) solution was carried out, before and after the filtration process using Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES), which showed a maximum of 50% reduction in its original concentration. The filtered membrane is analyzed for arsenic by Energy Dispersive X-ray (EDX) technique. Thus, the synthesized membrane effectively sieves the arsenic in water samples.
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•nZVI-kaol composites-based PES membrane is synthesized and used for As2O3 removal.•Irregular porosity of synthesized membrane has huge surface activity.•Existence of Fe0 in the composites is confirmed by XRD and FTIR.•Among the prepared membranes S3 nano composite membrane showed high removal efficiency of As2O3.•Removal efficiency of As2O3 greater than 50% was achieved.
A lot of the research has been done worldwide evaluating the capacity of the semitendinosus tendon to regenerate which has not been conducted in the Indian population.
31 patients who underwent ...unilateral ACL reconstruction with hamstrings were taken into study. All patients underwent ultrasonography imaging of both knees and bilateral isokinetic flexion strength assessment at a one-year postoperative period. Images were obtained at three levels and their dimensions are compared with normal side. Isokinetic testing of the knee is done to evaluate the flexion deficit and is compared to the uninvolved knee.
Out of a total of 31 patients, 14 patients showed no regeneration, 17 showed regeneration at various levels. On isokinetic testing patients with no regeneration showed the highest mean flexion deficit.
The semitendinosus tendon and its regeneration can be visualized well using ultrasonography. After semitendinosus harvesting, the flexion strength will be decreased as compared to the normal knee. The flexion strength in patients who have a regenerated tendon will be higher as compared to those who have no regeneration.
Alzheimer’s disease is a devastating neurodegenerative disorder, the most common among the dementing illnesses. Acetaminophen has gaining importance in neurodegenerative diseases by attenuating the ...dopaminergic neurodegeneration in Caenorhabditis elegans model, decreasing the chemokines and the cytokines and increasing the anti apoptotic protein such as Bcl-2 in neuronal cell culture. The low concentration acetaminophen improved the facilitation to find the hidden platform in Morris Water Maze Test. Also some data suggest that acetaminophen could contribute in neurodegeneration. The present study was aimed to evaluate the effect of acetaminophen against colchicine induced cognitive impairment and oxidative stress in wistar rats. The cognitive learning and memory behaviour was assessed using step through passive avoidance paradigm and acetylcholine esterase activity. The parameters of oxidative stress were assessed by measuring the malondialdehyde, reduced glutathione and catalase levels in the whole brain homogenates. There was a significant memory improvement in the rats received acetaminophen treatment and it has also decreased the acetylcholine esterase enzyme level, confirming its nootropic activity. Acetaminophen neither increases nor decreases the reduced glutathione and catalase in the whole brain homogenates, showing that acetaminophen is devoid of any adverse effect on brain antioxidant defense system.
Objective
To quantify the risk of ectopic pregnancy among a transient diagnosis of pregnancy of unknown location (PUL).
Methods
Retrospective cohort study between August 2016 and November 2020. The ...final cohort included 244 patients with 255 PULs who presented with vaginal bleeding and/or abdominal pain, positive serum quantitative β‐human chorionic gonadotropin, and negative transvaginal ultrasound, with a subsequent definitive diagnosis. Two‐way analysis of variance was used with significance set at P < 0.050. Bonferroni‐corrected significance values were used in post hoc analysis. Multinominal logistic regression was used to predict adjusted risk for pregnancy outcome.
Results
Definitive diagnosis consisted of 101 (39%) intrauterine pregnancies, 33 (13%) ectopic pregnancies, and 121 (48%) resolved PULs or resolved/treated persisting PULs. A total 68% of the PULs subsequently became nonviable. Vaginal bleeding was associated with increased risk of nonuterine pregnancies.
Conclusion
A total of 13% of PULs were subsequently diagnosed as ectopic pregnancies, which is higher than the 2% to 3% risk of an ectopic pregnancy in the general reproductive population. A total of 68% of PULs were subsequently nonviable, which is higher than the 31% early pregnancy loss rate in the general reproductive population. This study quantitatively confirms that a transient diagnosis of a PUL increases the odds for ectopic pregnancy and early pregnancy loss.
Synopsis
A total of 13% of pregnancies of unknown location were subsequently diagnosed as ectopic pregnancies, and 68% of pregnancies of unknown location subsequently were nonviable pregnancies. These rates are significantly higher than in the general reproductive population.
Proso millet national variety TNAU 202 A. Nirmalakumari, A. Subramanian, S. Manoharan, T. Raguchander, P. Veerabadhiran, K. Thiyagarajan, M. Paramathma and C. Priyadharshini
Electronic journal of plant breeding,
04/2021, Letnik:
12, Številka:
1
Journal Article
Recenzirano
Odprti dostop
A superior Proso millet culture, TNAU 202, was bred at the Department of Millets, CPBG, Tamil Nadu Agricultural University, Coimbatore and tested throughout the country for three years (2008 to ...2010). Being a profusely tillering, short duration ( 73 days) culture with better culm strength, it is best suited for the drylands of India. It is a derivative of the cross involving PV 1453 x GPUP 16. It yields on average, 1872 kg/ha of grain and 3700 kg/ha of straw during kharif season. The panicle is loose and branched with more number of grains. The grains are medium bold with desirable grain and cooking qualities. Since it is a short duration crop, it is very well suited for contingency planting. It recorded an increased grain yield of 26.23 and 15.06 per cent over qualifying varieties TNAU 196 and TNAU 201, respectively in All India Coordinated Trials. It recorded 19.16 per cent increased yield over the check TNAU 145, 15.34 per cent over TNAU 151, 31.09 per cent over GPUP 21 and 7.10 per cent as compared to the K1. Hence, TNAU 202 was released for cultivation in different states of the country in the year 2011.
Pudendal nerve block is an important alternative to neuraxial anesthesia, yet studies demonstrate that 3% to 50% of pudendal nerve blocks are ineffective. Lack of clinician training is the most ...common cause, and there are no simulation models currently described.
To develop and test a novel, low-cost, low-fidelity simulation model for training residents in the placement of a pudendal nerve block.
A pudendal nerve block model was developed using commonly found supplies, with a cost of $20.57. First-year to fourth-year obstetrics and gynecology (OB/GYN) and family medicine (FM) residents were invited to 1 of 4 pudendal nerve block 1-hour simulation sessions from December 2019 to March 2021 during their required teaching sessions. Expert faculty led a discussion of pudendal nerve blocks, then participants practiced with the described model. A survey about the model was created by the authors and administrated prior to and immediately after the session. Pre- and post-surveys were analyzed by Wilcoxon signed rank tests, and Bonferroni correction was performed.
Thirty-four out of a total of 36 eligible residents participated (94%). Residents showed improvement in knowledge (median pre-simulation score 43.99 compared with 70.06 post-simulation,
<.00625) and self-assessed confidence (median pre-simulation score 1.7 compared with 3.2 post-simulation,
<.00625) of a pudendal block placement after simulation training.
This new, low-cost, reusable, low-fidelity simulation model for pudendal nerve block placement improved knowledge and confidence in OB/GYN and FM residents after 1 hour of simulation training.
Nano-sized aluminium oxide powder has been synthesized in a thermal plasma reactor by in-flight oxidation of aluminium metal. The particle size of alumina formed ranges from a few nanometers to 30 ...nm. Experimental studies have been complemented by numerical process simulation using a one-dimensional model.