The authors greatly appreciated the implications of the study by Pan and associates,1 which determined whether some patients with newly diagnosed central serous chorioretinopathy (CSC) may be ...candidates for evaluation for obstructive sleep apnea (OSA). UED is derived from the authors’ published data from the Lateralising Eyelid Sleep Compression study by Figueira and associates, in Ophthalmic Plastic and Reconstructive Surgery in 2014. ...sight-threatening complications of OSA including nonarteritic anterior ischaemic optic neuropathy and normal pressure glaucoma can be diagnosed and managed in a timely fashion.
Ultrasound-guided interscalene nerve block (UISB) is commonly used to alleviate postoperative pain during shoulder arthroscopy. This retrospective observational study aimed to evaluate the ...intraoperative advantages and analgesic effects of preoperative UISB.
In this retrospective observational study, a total of 170 patients underwent shoulder arthroscopy at a tertiary medical center in southern Taiwan throughout 2019. After applying the exclusion criteria, 142 of these cases were included, with 74 and 68 in the UISB group and control groups, respectively. The primary outcome was the evaluation of intraoperative morphine milligram equivalent (MME) consumption. Secondary outcomes were sevoflurane consumption, the use of intraoperative antihypertensive drugs, and postoperative visual analog scale (VAS) scores in the post-anesthesia care unit (PACU) and in the ward at 24 h after surgery.
Preoperative UISB effectively reduced opioids and volatile gases during surgery, supported by a 48.1% and 14.8% reduction in the median intraoperative MME and sevoflurane concentrations, respectively, and showed less need for antihypertensive drugs. The preoperative UISB group also showed significantly better performance on the VAS in both the PACU and ward.
Taken together, the preoperative UISB reduced not only intraoperative MME and sevoflurane consumption but also had satisfactory VAS scores in both the PACU and ward without any symptomatic respiratory complications. In summary, preoperative UISB is a reliable adjuvant analgesic technique and a key factor in achieving opioid-sparing and sevoflurane-sparing anesthesia and multimodal analgesia during shoulder arthroscopy.
Background Cohort studies evaluating increased uric acid level as a cardiovascular disease (CVD) risk factor have shown variable results; studies are particularly lacking in lower risk populations. ...Study Design Prospective cohort study. Setting & Participants 484,568 adults participating in a medical screening program in Taiwan since 1994 were followed up for a median of 8.5 years. Two subgroups were constructed: the first (n = 246,697; 51%) excluded participants with either overt CVD or overt CVD risk factors (including hypertension, diabetes, obesity, and hypertriglyceridemia) and the second (n = 157,238; 32%) further excluded individuals with early-stage CVD risk factors (including prehypertension, prediabetes, overweight, and borderline hypertriglyceridemia). Predictor Serum uric acid. Outcomes & Measurements All-cause and CVD mortality risk assessed using Cox proportional hazards models for categorical and continuous serum uric acid levels. As applicable, models adjusted for 14 variables. Population-attributable fraction was applied to compare contributions to mortality between high uric acid level and other CVD risk factors. Results In the total cohort, mean age was 41.4 ± 14.0 years and 26.2% had serum uric acid levels ≥7 mg/dL. Through 2007, there were 16,246 deaths (3.4% of all participants), with 35.2% of deaths occurring in individuals with hyperuricemia. Adjusted HRs associated with serum uric acid levels ≥7 mg/dL for all-cause and CVD mortality were 1.10 (95% CI, 1.04-1.17) and 1.38 (95% CI, 1.20-1.58), respectively. In individuals with hyperuricemia, 64.3% had overt CVD risk factors and 82.5% had either overt or early-stage CVD risk factors. Individuals with serum uric acid levels ≥8 mg/dL without overt CVD risk factors constituted 13.5% of the total study population with hyperuricemia; in analyses excluding those with overt CVD risk factors, serum uric acid level ≥8 mg/dL was significantly associated with all-cause and CVD mortality, with HRs of 1.37 (95% CI, 1.18-1.60) and 2.30 (95% CI, 1.51-3.49), respectively. In the subgroup of those with serum uric acid levels ≥8 mg/dL but who lacked both overt and early-stage CVD risk factors, the HRs for all-cause and CVD mortality were also significant and were 1.39 (95% CI, 1.08-1.78) and 2.38 (95% CI, 1.24-4.54), respectively. HRs for individuals with the same risk profiles but with serum uric acid of 7.0-7.9 mg/dL were not significant. In all groups, inclusion of proteinuria and glomerular filtration rate in models substantially attenuated the association between uric acid level and outcomes. High uric acid levels contributed a relatively insignificant portion to mortality (1.2%) and CVD deaths (4.5%) in this population. Limitations A single measurement of uric acid was used. Conclusion Increased serum uric acid level is a minor, but significant, risk factor for all-cause and CVD mortality. However, except for a small proportion (13.5%), increased serum uric acid level is more a risk marker than a target for treatment and is not an independent risk. Determining appropriate groups to target in clinical trials for uric acid–lowering therapy is critical.
Context.
Ultra-short-period (USP) planets are defined as planets with orbital periods shorter than one day. This type of planets is rare, highly irradiated, and interesting because their formation ...history is unknown.
Aims.
We aim to obtain precise mass and radius measurements to confirm the planetary nature of a USP candidate found by the Transiting Exoplanet Survey Satellite (TESS). These parameters can provide insights into the bulk composition of the planet candidate and help to place constraints on its formation history.
Methods.
We used TESS light curves and HARPS-N spectrograph radial velocity measurements to establish the physical properties of the transiting exoplanet candidate found around the star HD 20329 (TOI-4524). We performed a joint fit of the light curves and radial velocity time series to measure the mass, radius, and orbital parameters of the candidate.
Results.
We confirm and characterize HD 20329b, a USP planet transiting a solar-type star. The host star (HD 20329,
V
= 8.74 mag,
J
= 7.5 mag) is characterized by its G5 spectral type with
M
*
= 0.90 ± 0.05
M
⊙
,
R
*
= 1.13 ± 0.02
R
⊙
, and
T
eff
= 5596 ± 50 K; it is located at a distance
d
= 63.68 ± 0.29 pc. By jointly fitting the available TESS transit light curves and follow-up radial velocity measurements, we find an orbital period of 0.9261 ± (0.5 × 10
−4
) days, a planetary radius of 1.72 ± 0.07
R
⊗
, and a mass of 7.42 ± 1.09
M
⊗
, implying a mean density of
ρ
p
= 8.06 ± 1.53 g cm
−3
. HD 20329b joins the ~30 currently known USP planets with radius and Doppler mass measurements.
ABSTRACT
We report the discovery of a planetary system orbiting TOI-763(aka CD-39 7945), a V = 10.2, high proper motion G-type dwarf star that was photometrically monitored by the TESS space mission ...in Sector 10. We obtain and model the stellar spectrum and find an object slightly smaller than the Sun, and somewhat older, but with a similar metallicity. Two planet candidates were found in the light curve to be transiting the star. Combining TESS transit photometry with HARPS high-precision radial velocity (RV) follow-up measurements confirm the planetary nature of these transit signals. We determine masses, radii, and bulk densities of these two planets. A third planet candidate was discovered serendipitously in the RV data. The inner transiting planet, TOI-763 b, has an orbital period of Pb = 5.6 d, a mass of Mb = 9.8 ± 0.8 M⊕, and a radius of Rb = 2.37 ± 0.10 R⊕. The second transiting planet, TOI-763 c, has an orbital period of Pc = 12.3 d, a mass of Mc = 9.3 ± 1.0 M⊕, and a radius of Rc = 2.87 ± 0.11 R⊕. We find the outermost planet candidate to orbit the star with a period of ∼48 d. If confirmed as a planet, it would have a minimum mass of Md = 9.5 ± 1.6 M⊕. We investigated the TESS light curve in order to search for a mono transit by planet d without success. We discuss the importance and implications of this planetary system in terms of the geometrical arrangements of planets orbiting G-type stars.
This study assessed the concurrent and construct validity of the Borg 6–20 Scale and WHEEL Scale during arm ergometry exercise stress testing in (n = 24) adolescents and adults with spina bifida. ...Significant, moderate, positive correlations were observed between power output and relative heart rate and power output to relative VO2peak. Further, a moderate, significant correlation between physiologic criterion variables and the rating of perceived exertion derived from the Borg Scale and the WHEEL Scale was found. Concurrent validity was supported by the following findings: (1) relative heart rate was significantly correlated with the Borg (Kendall's τ = .41) and WHEEL Scales (τ = .44), and relative VO2 was significantly correlated with the Borg (τ = .46) and WHEEL Scales (τ = .47); (2) content validity was supported by the finding that the Borg and WHEEL Scales shared significant variance (τ = .70), demonstrating internal consistency. The WHEEL Scale shows strong potential for use in this cohort subsequent to further testing and validation.
This is the sixth in a series of papers where we bring collaborating mycologists together to produce a set of notes of several taxa of fungi. In this study we introduce a new family
...Fuscostagonosporaceae
in Dothideomycetes. We also introduce the new ascomycete genera
Acericola
,
Castellaniomyces
,
Dictyosporina
and
Longitudinalis
and new species
Acericola italica
,
Alternariaster trigonosporus
,
Amarenomyces dactylidis
,
Angustimassarina coryli
,
Astrocystis bambusicola
,
Castellaniomyces rosae
,
Chaetothyrina artocarpi
,
Chlamydotubeufia krabiensis
,
Colletotrichum lauri
,
Collodiscula chiangraiensis
,
Curvularia palmicola
,
Cytospora mali
-
sylvestris
,
Dictyocheirospora cheirospora
,
Dictyosporina ferruginea
,
Dothiora coronillae
,
Dothiora spartii
,
Dyfrolomyces phetchaburiensis
,
Epicoccum cedri
,
Epicoccum pruni
,
Fasciatispora calami
,
Fuscostagonospora cytisi
,
Grandibotrys hyalinus
,
Hermatomyces nabanheensis
,
Hongkongmyces thailandica
,
Hysterium rhizophorae
,
Jahnula guttulaspora
,
Kirschsteiniothelia rostrata
,
Koorchalomella salmonispora
,
Longitudinalis nabanheensis
,
Lophium zalerioides
,
Magnibotryascoma mali
,
Meliola clerodendri
-
infortunati
,
Microthyrium chinense
,
Neodidymelliopsis moricola
,
Neophaeocryptopus spartii
,
Nigrograna thymi
,
Ophiocordyceps cossidarum
,
Ophiocordyceps issidarum
,
Ophiosimulans plantaginis
,
Otidea pruinosa
,
Otidea stipitata
,
Paucispora kunmingense
,
Phaeoisaria microspora
,
Pleurothecium floriforme
,
Poaceascoma halophila
,
Periconia aquatica
,
Periconia submersa
,
Phaeosphaeria acaciae
,
Phaeopoacea muriformis
,
Pseudopithomyces kunmingnensis
,
Ramgea ozimecii
,
Sardiniella celtidis
,
Seimatosporium italicum
,
Setoseptoria scirpi
,
Torula gaodangensis
and
Vamsapriya breviconidiophora
. We also provide an amended account of
Rhytidhysteron
to include apothecial ascomata and a J+ hymenium. The type species of
Ascotrichella hawksworthii
(
Xylariales genera incertae sedis
),
Biciliopsis leptogiicola
(
Sordariomycetes genera incertae sedis
),
Brooksia tropicalis
(
Micropeltidaceae
),
Bryochiton monascus
(
Teratosphaeriaceae
),
Bryomyces scapaniae
(
Pseudoperisporiaceae
),
Buelliella minimula
(
Dothideomycetes genera incertae sedis
),
Carinispora nypae
(
Pseudoastrosphaeriellaceae
),
Cocciscia hammeri
(
Verrucariaceae
),
Endoxylina astroidea
(
Diatrypaceae
),
Exserohilum turcicum
(
Pleosporaceae
),
Immotthia hypoxylon
(
Roussoellaceae
),
Licopolia franciscana
(
Vizellaceae
),
Murispora rubicunda
(
Amniculicolaceae
) and
Doratospora guianensis
(synonymized under
Rizalia guianensis
,
Trichosphaeriaceae
) were re-examined and descriptions, illustrations and discussion on their familial placement are given based on phylogeny and morphological data. New host records or new country reports are provided for
Chlamydotubeufia huaikangplaensis
,
Colletotrichum fioriniae
,
Diaporthe subclavata
,
Diatrypella vulgaris
,
Immersidiscosia eucalypti
,
Leptoxyphium glochidion
,
Stemphylium vesicarium
,
Tetraploa yakushimensis
and
Xepicula leucotricha
.
Diaporthe baccae
is synonymized under
Diaporthe rhusicola.
A reference specimen is provided for
Periconia minutissima.
Updated phylogenetic trees are provided for most families and genera. We introduce the new basidiomycete species
Agaricus purpurlesquameus
,
Agaricus rufusfibrillosus
,
Lactifluus holophyllus
,
Lactifluus luteolamellatus
,
Lactifluus pseudohygrophoroides
,
Russula benwooii
,
Russula hypofragilis
,
Russula obscurozelleri
,
Russula parapallens
,
Russula phoenicea
,
Russula pseudopelargonia
,
Russula pseudotsugarum
,
Russula rhodocephala
,
Russula salishensis
,
Steccherinum amapaense
,
Tephrocybella constrictospora
,
Tyromyces amazonicus
and
Tyromyces angulatus
and provide updated trees to the genera. We also introduce
Mortierella formicae
in
Mortierellales
, Mucoromycota and provide an updated phylogenetic tree.
Taxonomic names are key links between various databases that store information on different organisms. Several global fungal nomenclural and taxonomic databases (notably Index Fungorum, Species ...Fungorum and MycoBank) can be sourced to find taxonomic details about fungi, while DNA sequence data can be sourced from NCBI, EBI and UNITE databases. Although the sequence data may be linked to a name, the quality of the metadata is variable and generally there is no corresponding link to images, descriptions or herbarium material. There is generally no way to establish the accuracy of the names in these genomic databases, other than whether the submission is from a reputable source. To tackle this problem, a new database (FacesofFungi), accessible at www.facesoffungi.org (FoF) has been established. This fungal database allows deposition of taxonomic data, phenotypic details and other useful data, which will enhance our current taxonomic understanding and ultimately enable mycologists to gain better and updated insights into the current fungal classification system. In addition, the database will also allow access to comprehensive metadata including descriptions of voucher and type specimens. This database is user-friendly, providing links and easy access between taxonomic ranks, with the classification system based primarily on molecular data (from the literature and via updated web-based phylogenetic trees), and to a lesser extent on morphological data when molecular data are unavailable. In FoF species are not only linked to the closest phylogenetic representatives, but also relevant data is provided, wherever available, on various applied aspects, such as ecological, industrial, quarantine and chemical uses. The data include the three main fungal groups (Ascomycota, Basidiomycota, Basal fungi) and fungus-like organisms. The FoF webpage is an output funded by the Mushroom Research Foundation which is an NGO with seven directors with mycological expertise. The webpage has 76 curators, and with the help of these specialists, FoF will provide an updated natural classification of the fungi, with illustrated accounts of species linked to molecular data. The present paper introduces the FoF database to the scientific community and briefly reviews some of the problems associated with classification and identification of the main fungal groups. The structure and use of the database is then explained. We would like to invite all mycologists to contribute to these web pages.
This is a continuity of a series of taxonomic papers where materials are examined, described and novel combinations are proposed where necessary to improve our traditional species concepts and ...provide updates on their classification. In addition to extensive morphological descriptions and appropriate asexual and sexual connections, DNA sequence data are also analysed from concatenated datasets (rDNA, TEF-α, RBP2 and β-Tubulin) to infer phylogenetic relationships and substantiate systematic position of taxa within appropriate ranks. Wherever new species or combinations are being proposed, we apply an integrative approach (morphological and molecular data as well as ecological features wherever applicable). Notes on 125 fungal taxa are compiled in this paper, including eight new genera, 101 new species, two new combinations, one neotype, four reference specimens, new host or distribution records for eight species and one alternative morphs. The new genera introduced in this paper are
Alloarthopyrenia
,
Arundellina
,
Camarosporioides
,
Neomassaria
,
Neomassarina
,
Neotruncatella
,
Paracapsulospora
and
Pseudophaeosphaeria
. The new species are
Alfaria spartii
,
Alloarthopyrenia italica
,
Anthostomella ravenna
,
An
.
thailandica
,
Arthrinium paraphaeospermum
,
Arundellina typhae
,
Aspergillus koreanus
,
Asterina cynometrae
,
Bertiella ellipsoidea
,
Blastophorum aquaticum
,
Cainia globosa
,
Camarosporioides phragmitis
,
Ceramothyrium menglunense
,
Chaetosphaeronema achilleae
,
Chlamydotubeufia helicospora
,
Ciliochorella phanericola
,
Clavulinopsis aurantiaca
,
Colletotrichum insertae
,
Comoclathris italica
,
Coronophora myricoides
,
Cortinarius fulvescentoideus
,
Co
.
nymphatus
,
Co
.
pseudobulliardioides
,
Co
.
tenuifulvescens
,
Cunninghamella gigacellularis
,
Cyathus pyristriatus
,
Cytospora cotini
,
Dematiopleospora alliariae
,
De
.
cirsii
,
Diaporthe aseana
,
Di
.
garethjonesii
,
Distoseptispora multiseptata
,
Dis
.
tectonae
,
Dis
.
tectonigena
,
Dothiora buxi
,
Emericellopsis persica
,
Gloniopsis calami
,
Helicoma guttulatum
,
Helvella floriforma
,
H
.
oblongispora
,
Hermatomyces subiculosa
,
Juncaceicola italica
,
Lactarius dirkii
,
Lentithecium unicellulare
,
Le
.
voraginesporum
,
Leptosphaeria cirsii
,
Leptosphaeria irregularis
,
Leptospora galii
,
Le
.
thailandica
,
Lindgomyces pseudomadisonensis
,
Lophiotrema bambusae
,
Lo
.
fallopiae
,
Meliola citri-maximae
,
Minimelanolocus submersus
,
Montagnula cirsii
,
Mortierella fluviae
,
Muriphaeosphaeria ambrosiae
,
Neodidymelliopsis ranunculi
,
Neomassaria fabacearum
,
Neomassarina thailandica
,
Neomicrosphaeropsis cytisi
,
Neo
.
cytisinus
,
Neo
.
minima
,
Neopestalotiopsis cocoës
,
Neopestalotiopsis musae
,
Neoroussoella lenispora
,
Neotorula submersa
,
Neotruncatella endophytica
,
Nodulosphaeria italica
,
Occultibambusa aquatica
,
Oc
.
chiangraiensis
,
Ophiocordyceps hemisphaerica
,
Op
.
lacrimoidis
,
Paracapsulospora metroxyli
,
Pestalotiopsis sequoiae
,
Peziza fruticosa
,
Pleurotrema thailandica
,
Poaceicola arundinis
,
Polyporus mangshanensis
,
Pseudocoleophoma typhicola
,
Pseudodictyosporium thailandica
,
Pseudophaeosphaeria rubi
,
Purpureocillium sodanum
,
Ramariopsis atlantica
,
Rhodocybe griseoaurantia
,
Rh
.
indica
,
Rh
.
luteobrunnea
,
Russula indoalba
,
Ru
.
pseudoamoenicolor
,
Sporidesmium aquaticivaginatum
,
Sp
.
olivaceoconidium
,
Sp
.
pyriformatum
,
Stagonospora forlicesenensis
,
Stagonosporopsis centaureae
,
Terriera thailandica
,
Tremateia arundicola
,
Tr
.
guiyangensis
,
Trichomerium bambusae
,
Tubeufia hyalospora
,
Tu
.
roseohelicospora
and
Wojnowicia italica
. New combinations are given for
Hermatomyces mirum
and
Pallidocercospora thailandica
. A neotype is proposed for
Cortinarius fulvescens
. Reference specimens are given for
Aquaphila albicans
,
Leptospora rubella
,
Platychora ulmi
and
Meliola pseudosasae
, while new host or distribution records are provided for
Diaporthe eres
,
Di. siamensis
,
Di
.
foeniculina
,
Dothiorella iranica
,
Do. sarmentorum
,
Do. vidmadera
,
Helvella tinta
and
Vaginatispora fuckelii
, with full taxonomic details. An asexual state is also reported for the first time in
Neoacanthostigma septoconstrictum
. This paper contributes to a more comprehensive update and improved identification of many ascomycetes and basiodiomycetes.