We present the first measurement of the two-particle transverse momentum differential correlation function, P_{2}≡⟨Δp_{T}Δp_{T}⟩/⟨p_{T}⟩^{2}, in Pb-Pb collisions at sqrts_{NN}=2.76 TeV. Results for ...P_{2} are reported as a function of the relative pseudorapidity (Δη) and azimuthal angle (Δφ) between two particles for different collision centralities. The Δϕ dependence is found to be largely independent of Δη for |Δη|≥0.9. In the 5% most central Pb-Pb collisions, the two-particle transverse momentum correlation function exhibits a clear double-hump structure around Δφ=π (i.e., on the away side), which is not observed in number correlations in the same centrality range, and thus provides an indication of the dominance of triangular flow in this collision centrality. Fourier decompositions of P_{2}, studied as a function of the collision centrality, show that correlations at |Δη|≥0.9 can be well reproduced by a flow ansatz based on the notion that measured transverse momentum correlations are strictly determined by the collective motion of the system.
The NA50 Collaboration has measured heavy-quarkonium production in p–A collisions at 450 GeV incident energy (s=29.1 GeV). We report here results on the production of the ϒ states and of high-mass ...Drell–Yan muon pairs (mμμ>6 GeV/c2). The cross-section at midrapidity and the A-dependence of the measured yields are determined and compared with the results of other fixed-target experiments and with the available theoretical estimates. Finally, we also address some issues concerning the transverse momentum distributions of the measured dimuons.
The production of \({\rm J}/\psi\) and \(\psi^\prime\) charmonium states in proton-nucleus interactions has been investigated by the NA50 experiment, at the CERN SPS. High statistics data sets were ...collected with collisions induced by 450 GeV protons incident on Be, Al, Cu, Ag and W targets. The \({\rm J}/\psi\) and \(\psi^\prime\) production cross-sections have been determined for each p-A system and their dependences on the nucleus size have been studied, leading to the so-called normal nuclear absorption. Comparing the two patterns we see that the nuclear absorption is stronger for the \(\psi^\prime\) than for the \({\rm J}/\psi\). Given the high statistics of the data samples, the \(x_{\rm F}\) (or rapidity) differential cross-sections of the \({\rm J}/\psi\) and \(\psi^\prime\) states have also been studied, for each of the target nuclei.
Patients with irritable bowel syndrome (IBS) often associate their symptoms to certain foods. In congenital sucrase-isomaltase deficiency (CSID), recessive mutations in the SI gene (coding for the ...disaccharidase digesting sucrose and 60% of dietary starch)1 cause clinical features of IBS through colonic accumulation of undigested carbohydrates, triggering bowel symptoms.2 Hence, in a previous study,3 we hypothesized that CSID variants reducing SI enzymatic activity may contribute to development of IBS symptoms. We detected association with increased risk of IBS for 4 rare loss-of-function variants typically found in (homozygous) CSID patients, because carriers (heterozygous) of these rare variants were more common in patients than in controls.1,4 Through a 2-step computational and experimental strategy, the present study aimed to determine whether other (dys-)functional SI variants are associated with risk of IBS in addition to known CSID mutations. We first aimed to identify all SI rare pathogenic variants (SI-RPVs) on the basis of integrated Mendelian Clinically Applicable Pathogenicity (M-CAP) and Combined Annotation Dependent Depletion (CADD) predictive (clinically relevant) scores; next, we inspected genotype data currently available for 2207 IBS patients from a large ongoing project to compare SI-RPV case frequencies with ethnically matched population frequencies from the Exome Aggregation Consortium (ExAC).
The J/ $\psi$ normal nuclear absorption Borges, G.
European Physical Journal C: Particles and Fields,
08/2005, Letnik:
43, Številka:
1-4
Journal Article, Conference Proceeding
Recenzirano
We present a new determination of the ratio of cross-sections (J/$\psi$)/DY as expected for nucleus-nucleus reactions if J/$\psi$ would only be normally absorbed by nuclear matter. This anticipated ...behaviour is based on proton-nucleus data exclusively, and compared, as a function of centrality, with updated S-U results from experiment NA38 and with the most Pb-Pb results from experiment NA50.
Operation and performance of the NA60 silicon pixel telescope Banicz, K.; David, A.; Floris, M. ...
Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment,
02/2005, Letnik:
539, Številka:
1
Journal Article
Recenzirano
Odprti dostop
The NA60 experiment studies open charm and prompt dimuon production in proton–nucleus and nucleus–nucleus collisions at the CERN SPS. The high multiplicity of charged tracks produced in heavy-ion ...collisions imposes the use of silicon pixel detectors to perform an efficient tracking. This paper describes the design and assembly of the pixel telescope and performance results from three detector planes operated in the high charged particle multiplicity conditions of Pb–Pb collisions.
The motor response to vasopressin, a neuropeptide promoting the reabsorption of water, was isometrically investigated in vitro in human renal calyces and pelvis in relation to possible modulation of ...urinary flow by these tubular structures. Kidneys were obtained from nine male patients who underwent nephrectomy for either renal or ureteral cancer. Minor calyces and pelvis were carefully removed. Strips (10
mm × 3
mm) were cut from infundibular region of minor calyces and from renal pelvis and placed in 10
ml organ bath for isometric tension recordings. Calyceal and pelvic smooth muscle strips exhibited spontaneous phasic contractions which occurred with regular frequency and amplitude. Vasopressin induced a dose-dependent 10
−10 to 10
−6
M enhancement of basal tone (
P < 0.01) and a decrease of spontaneous contractions on isolated strips from minor calyces and pelvis. The effect of vasopressin was inhibited by prior administration of D(CH
2)
5Tyr(Me)
2-Arg
8-Vasopressin antagonist 10
−7
M. The excitatory response to vasopressin was Tetrodotoxin TTX-resistant and was not affected by pre-treatment with phentolamine 10
−5
M, atropine 10
−5
M, and hexamethonium 10
−5
M. After incubation of the specimens in Ca
2+-free medium containing EGTA 0.5
mM or after treatment with nifedipine 10
−5
M, both spontaneous and vasopressin-induced contractions 10
−10 to 10
−6
M were completely inhibited in all specimens. Our results can be interpreted to imply that the tonic contractions induced by vasopressin facilitate the reabsorption of water by increasing the hydraulic resistance of the tubular structures below collecting ducts.
Charmonium production in p–A collisions is a unique tool for the study of the interaction of bound cc states in nuclear matter. It can provide details on the basic features of the resonance formation ...mechanism and, in particular, on its non-perturbative aspects. In this Letter, we present an experimental study of charmonia and Drell–Yan production in proton–nucleus collisions at 450 GeV/c. The results are analyzed in the framework of the Glauber model and lead to the values of the nuclear absorption cross-section σabspA for J/ψ and ψ′. Then, we compare the J/ψ absorption in proton–nucleus and sulphur–uranium interactions, using NA38 data. We obtain that, for the J/ψ, σabspA and σabsSU are compatible, showing that no sizeable additional suppression mechanism is present in S–U collisions, and confirming that the anomalous J/ψ suppression only sets in for Pb–Pb interactions.
Breath tests represent a valid and non-invasive diagnostic tool in many gastroenterological conditions. The rationale of hydrogen-breath tests is based on the concept that part of the gas produced by ...colonic bacterial fermentation diffuses into the blood and is excreted by breath, where it can be quantified easily. There are many differences in the methodology, and the tests are increasingly popular.
The Rome Consensus Conference was convened to offer recommendations for clinical practice about the indications and methods of H2-breath testing in gastrointestinal diseases.
Experts were selected on the basis of a proven knowledge/expertise in H2-breath testing and divided into Working Groups (methodology; sugar malabsorption; small intestine bacterial overgrowth; oro-coecal transit time and other gas-related syndromes). They performed a systematic review of the literature, and then formulated statements on the basis of the scientific evidence, which were debated and voted by a multidisciplinary Jury. Recommendations were then modified on the basis of the decisions of the Jury by the members of the Expert Group.
The final statements, graded according to the level of evidence and strength of recommendation, are presented in this document; they identify the indications for the use of H2-breath testing in the clinical practice and methods to be used for performing the tests.
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