Probiotics are effective for treating acute infectious diarrhoea caused by bacteria, but there are inconsistent results for the effectiveness of probiotics for diarrhoea caused by viruses. In this ...article we want to determine whether Sb supplementation has an effect on acute inflammatory viral diarrhoea diagnosed with the multiplex panel PCR test. The aim of this study was to evaluate the efficacy of Saccharomyces boulardii (Sb) as a treatment in patients diagnosed with viral acute diarrhoea.
From February 2021 to December 2021, 46 patients with a confirmed diagnosis of viral acute diarrhoea diagnosed with the polymerase chain reaction multiplex assay were enrolled in a double-blind, randomized placebo-controlled trial. Patients received paracetamol 500 mg as a standard analgesic and 200 mg of Trimebutine as an antispasmodic treatment plus 600 mg of Sb (n = 23, 1 × 109/100 mL Colony forming unit) or a placebo (n = 23) orally once daily for eight days. The improvement in and severity of symptoms were measured using a symptom diary, the Patient Global Impression and the Patient Global Impression of Change scales (days 4 and 8), both answered and recorded by the patient.
Of the 46 patients who completed treatment, 24 (52%) were men and 22 (48%) were women. The average age was 35.6 ± 12.28 years (range 18 to 61 years). The average duration of the evolution of illness at the time of diagnosis was 0.85 ± 0.73 days (maximum 2 days). On day 4 after the diagnosis, 20% reported pain and 2% reported fever, but on day 8, no patient reported pain or fever. On day 4, 70% of patients in the Sb group and 26% in the placebo group reported improvement (P = 0.03), based on the Patients' Global Impression of Change scale, which assesses patient's rating of overall improvement. These findings suggest that 3 to 4 days of treatment with Sb helped to improve symptoms of diarrhoea caused by a virus.
Treatment with Sb on acute inflammatory diarrhoea of viral aetiology shows no changes regarding the severity of the symptoms; nevertheless, it seems to impact improvement positively.
22CEI00320171130 dated on 16/12/2020, NCT05226052 dated on 07/02/2022.
En este trabajo se estudiaron las propiedades psicométricas de la prueba Body Image Anxiety Scale (bias) versión rasgo. La muestra fue de 2 mil 089 sujetos (902 mujeres y 1 mil 187 hombres), alumnos ...de primer ingreso a las licenciaturas que se ofrecen en la Universidad Autónoma de Chihuahua, con una edad media de 18.23 años (de=0.74). El análisis de las propiedades psicométricas mostró que una estructura bifactorial es viable y adecuada de acuerdo a los requisitos psicométricos establecidos cuando los informantes son los propios alumnos. La estructura de dos factores, atendiendo a criterios estadísticos y sustantivos, mostró adecuados indicadores de ajuste, de fiabilidad y de validez. Además, los análisis factoriales llevados a cabo con las submuestras 1 y 2 indican que los resultados obtenidos son plenamente confirmatorios. Futuras investigaciones deberían replicar estos hallazgos en muestras más amplias.
In this paper the psychometric properties of the Body Image Anxiety Scale (bias) test were studied regarding the traits displayed by higher-education students. The sample included 2,089 freshmen subjects (902 females and 1,187 males) studying degree courses offered at the Autonomous University of Chihuahua, with an average age of 18.23 years (sd = 0.74). Analysis of the psychometric properties showed that a two-factor structure is both feasible and appropriate —in accordance with established psychometric requirements— when the interviewees are the students themselves. The two-factor structure — based on statistical and substantive criteria— showed adequate adjustment, reliability and validity. Furthermore, the factorial analysis —conducted with subsamples 1 and 2— indicates that the results are completely confirmatory. Future research should replicate these findings in larger samples.
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