Background & objectives: Immunocompromised cancer patients are venerable for the infection and so the professionals involved in radiotherapy too. The objective of this online survey was to assess the ...impact of Covid-19 on radiotherapy practices, safety measures taken by the radiotherapy professionals during the peak of Covid-19 infection in India. Methods: Structured questionnaire was shared online to assess the awareness and knowledge pertaining to safety of protective items, importance and method of screening, QA of the instruments, safety measures taken in radiotherapy department, methods of the sanitization, use of mask and methods of Covid-19 waste managements. Results: Survey results indicated that almost all participants (97.4%) were aware of the severity of Covid-19 virus. In safety at the individual level, 51.3% of the staff reported changing hand gloves before handling new patients and 41% did not follow the same. In this survey, regarding working days (in a week), employees were working for six days in 56.4% centres, 28.2 % centres for three days of a week and remaining 15.4% centres were operational with five days of week. At 38.5% centres, radiotherapy personals found infected with the virus however large number of centres (53.8%) revealed that so far, no radiotherapy professionals got infected. Interpretation & conclusions: The current survey comprised 31 questions pertaining to various aspects of radiotherapy practices and radiotherapy professional safety from Covid infections and changes followed due to Covid-19 epidemic. The individual professional’s inputs could help to deal with such epidemic in even better way.
A BSTRACT Aim: The aim of the present study is to propose an in-house developed artificial intelligence (AI) tool based on Python programming for the purpose of integral doses (IDs) calculation ...useful in plan evaluation in modern radiotherapy techniques. Materials and Methods: Retrospectively, curative radiotherapy plans of cancer head and neck planned with intensity-modulated radiation therapy techniques employing seven and nine photon beams of 6 MV, were included in this study. The derived dose-volume histogram data were analyzed for the calculation of ID for each of the contoured structures including high-risk planning target volume (HR-PTV) and surrounding normal structures using an in-house developed Python program. Results: In this study, variation of ID between nine-beam and seven-beam plans was calculated. It was found that the ID for HR-PTV volume was almost equal in both nine and seven beam plans with the percentage variation range 0.4%–1.4%, however, significant variation up to 14.4% in the ID of organ at risk was found. Furthermore, we utilized the standard deviation (SD) as a metric to assess the variability of the ID within the PTV and the surrounding normal tissues. The HR-PTV exhibited a low SD of 0.71, suggesting consistent ID patterns. In contrast, the organs at risk (OAR) exhibited noteworthy variations in SD values, with some reaching as high as 16.75. The SD was relatively elevated in the OAR in comparison to the HR-PTV. These elevated SD values within the OAR indicate significant dose variability across different patients. Conclusion: It is found that ID increases as the number of beams increases. The Python program used in this study for the calculation of ID, as an AI assistive tool for plan evaluation, can be run on the TPS or on a side-by-side computer which may be helpful in finalizing radiotherapy plans.
Aim: The present study was undertaken to evaluate the performance of different algorithms for flattening filter-free (FFF) and flattened (FF) photon beams in three different in-homogeneities.
...Materials and Method: Computed tomography (CT) image sets of the CIRS phantom maintained in the SAD setup by placing the ionization chamber in the lung, bone, and tissue regions, respectively, were acquired. The treatment planning system (TPS) calculated and the ionization chamber measured the doses at the center of the chamber (in the three mediums) were recorded for the flattened and non-flattened photon beams.
Results: The results were reported for photon energies of 6 MV, 10 MV, 15 MV, 6 FFF, and 10 FFF of field sizes 5 × 5 cm2, 10 × 10 cm2, and 15 × 15 cm2. In the bone inhomogeneity, the pencil beam algorithm predicted that the maximum dose variation was 4.88% of measured chamber dose in 10-MV photon energy for the field size 10 × 10 cm2. In water inhomogeneity, both the collapsed cone and Monte Carlo algorithm predicted that the maximum dose variation was ± 3% of measured chamber dose in 10-MV photon energy for the field size 10 × 10 cm2 and in 10-MV FFF photon energy for the field size 5 × 5 cm2, whereas in lung inhomogeneity, the pencil beam algorithm predicted that the highest dose variation was - 6.9% of measured chamber dose in 10-MV FFF photon energy for the field size 5 × 5 cm2.
Conclusion: FF and FFF beams performed differently in lung, water, and bone mediums. The assessment of algorithms was conducted using the anthropomorphic phantom; therefore, these findings may help in the selection of appropriate algorithms for particular clinical settings in radiation delivery.
Errors in the identification of true patients in a health-care facility may result in the wrong dose or dosage being given to the wrong patient at the wrong site during radiotherapy sessions, ...radiopharmaceutical administration, radiological scans, etc. The aim of this article is to reduce the error in the identification of correct patients by implementation of the Python deep learning-based real-time patient identification program.
The authors utilized and installed Anaconda Prompt (miniconda 3), Python (version 3.9.12), and Visual Studio Code (version 1.71.0) for the design of the patient identification program. In the field of view, the area of interest is merely face detection. The overall performance of the developed program is accomplished over three steps, namely image data collection, data transfer, and data analysis, respectively. The patient identification tool was developed using the OpenCV library for face recognition.
This program provides real-time patient identification information, together with the other preset parameters such as disease site, with a precision of 0.92%, recall rate of 0.80%, and specificity of 0.90%. Furthermore, the accuracy of the program was found to be 0.84%. The output of the in-house developed program as "Unknown" is provided if a patient's relative or an unknown person is found in restricted region.
This Python-based program is beneficial for confirming the patient's identity, without manual interventions, just before therapy, administering medications, and starting other medical procedures, among other things, to prevent unintended medical and health-related complications that may arise as a result of misidentification.
Purpose: The aim of the present study was to compare the positional accuracy of varian's exact-arm (E-arm) and retractable-arm (R-arm) supporting electronic portal imaging device (EPID) systems ...(amorphous silicon flat-panel detector) using the intensity-modulated radiotherapy (IMRT) graticule phantom.
Materials and Methods: The known shifts of 0.5, 1.0, and 1.5 cm were introduced to the given phantom in longitudinal, lateral, and vertical directions, respectively, with respect to treatment couch of medical linear accelerator. The experiment was repeated for different gantry angle and varying source to imager distances (SIDs). The images were acquired for each shift at varying SIDs and beam orientations for both EPID supporting systems. The corresponding shifts obtained from treatment planning system (TPS) were recorded and compared.
Results: The known (expected) and observed (recorded from TPS) shifts obtained for different beam angles (namely, 0°, 90°, 180°, and 270° for anterior, left lateral, posterior, and right-lateral portal images, respectively) in the longitudinal, lateral, and vertical direction at varying SID were compared. The maximum shift in the observed value from the expected one was 3 and 2 mm, respectively, out of the all beam configuration for R-arm and E-arm. These shifts were randomly observed for all imager position and beam orientation.
Conclusion: The IMRT graticule phantom is an effective tool to check the mechanical characteristic and consistency of different EPID supporting arms. The effect of EPID sag due to gravity (gantry and treatment couch) was not significant for detection of shift in patient's position. The E-arm support EPID has better mechanical stability and accuracy in detection of patient's position than that of R-arm.
Accurate dosimetry at the interface of two different density medium (e.g., air cavity in the head and neck cancers and lungs in thoracic region) is a major cause of concern in external beam radiation ...therapy. It has been observed that there is dose variation in and around air cavities, which occur as a result of the loss of both longitudinal and lateral electronic equilibrium. Heterogeneous structures with spatial differences in functionality and sensitivity for radiation pose challenge to radiation dosimetry. This study is an attempt to evaluate the dose perturbations produced at the interface of two medium for C0-60 gamma radiation.
Low density polyethene foam has been used to mimic air cavity. GAFCHROMIC EBT2 dosimetry film was used for the measurement of dose at different locations. Simulation studies were performed using DOSRZnrc user code that comes with EGSnrc V4 2.4.0. Cylindrical geometry is used for all the simulations.
We observed significant variation in dose for smaller fields. There is a dose build down in the backward region and a dose build up in the forward direction. In the region of electronic disequilibrium, dose reduction near interface (proximal end) will have negative impact if target region is embedded there, on the contrary, it would be beneficial if there is normal tissue/critical organ adjacent to it.