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zadetkov: 165
1.
  • Immune-checkpoint inhibitor... Immune-checkpoint inhibitors and metastatic prostate cancer therapy: Learning by making mistakes
    Claps, Mélanie; Mennitto, Alessia; Guadalupi, Valentina ... Cancer treatment reviews, August 2020, 2020-08-00, 20200801, Letnik: 88
    Journal Article
    Recenzirano

    •Metastatic castration resistant prostate cancer express PD-L1 in 32% of cases.•CDK12-mutations could predict response to PD-1/PD-L1 inhibitors.•Combinations with vaccines, hormones, PARPi and ...
Celotno besedilo
2.
  • Predictive Biomarkers of Re... Predictive Biomarkers of Response to Immunotherapy in Metastatic Renal Cell Cancer
    Raimondi, Alessandra; Sepe, Pierangela; Zattarin, Emma ... Frontiers in oncology, 08/2020, Letnik: 10
    Journal Article
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    In the last decades, the therapeutic decision-making approach to metastatic renal cell cancer (mRCC) has dramatically changed thanks to the introduction in the treatment scenario of, first, ...
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3.
  • The Evaluation of Response ... The Evaluation of Response to Immunotherapy in Metastatic Renal Cell Carcinoma: Open Challenges in the Clinical Practice
    Raimondi, Alessandra; Randon, Giovanni; Sepe, Pierangela ... International journal of molecular sciences, 08/2019, Letnik: 20, Številka: 17
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    Immunotherapy has changed the therapeutic scenario of metastatic renal cell carcinoma (mRCC), however the evaluation of disease response to immune-checkpoint inhibitors is still an open challenge. ...
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4.
  • Analysis of Single Circulat... Analysis of Single Circulating Tumor Cells in Renal Cell Carcinoma Reveals Phenotypic Heterogeneity and Genomic Alterations Related to Progression
    Cappelletti, Vera; Verzoni, Elena; Ratta, Raffaele ... International journal of molecular sciences, 02/2020, Letnik: 21, Številka: 4
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    Circulating tumor cells (CTCs) are promising biomarkers for prognosis, therapeutic response prediction, and treatment monitoring in cancer patients. Despite its epithelial origin, renal cell ...
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5.
  • Real-world efficacy and saf... Real-world efficacy and safety of nivolumab in previously-treated metastatic renal cell carcinoma, and association between immune-related adverse events and survival: the Italian expanded access program
    Verzoni, Elena; Cartenì, Giacomo; Cortesi, Enrico ... Journal for immunotherapy of cancer, 04/2019, Letnik: 7, Številka: 1
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    The Italian Renal Cell Cancer Early Access Program was an expanded access program that allowed access to nivolumab, for patients (pts) with metastatic renal cell carcinoma (mRCC) prior to regulatory ...
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6.
  • Combination Therapy in Rena... Combination Therapy in Renal Cell Carcinoma: the Best Choice for Every Patient?
    Rossi, Ernesto; Bersanelli, Melissa; Gelibter, Alain Jonathan ... Current oncology reports, 12/2021, Letnik: 23, Številka: 12
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    Purpose of Review Therapeutic alternatives to treat metastatic renal cell carcinoma (mRCC) are increasing, and combination therapies, including antiangiogenic agents and tyrosine kinase/mTOR/immune ...
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7.
  • Characteristics and Treatme... Characteristics and Treatment Challenges of Non-Clear Cell Renal Cell Carcinoma
    Sepe, Pierangela; Ottini, Arianna; Pircher, Chiara Carlotta ... Cancers, 07/2021, Letnik: 13, Številka: 15
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    Non-clear cell renal cell carcinomas (RCC) comprise several rare and poorly described diseases, often characterized by bad prognosis and with no standard treatments available. The gap in their ...
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8.
  • Clinical Impact of Pancreat... Clinical Impact of Pancreatic Metastases from Renal Cell Carcinoma: A Multicenter Retrospective Analysis
    Grassi, Paolo; Doucet, Ludovic; Giglione, Palma ... PloS one, 04/2016, Letnik: 11, Številka: 4
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    Pancreatic metastases from renal cell carcinoma are uncommon and their prognostic significance is not well defined. In this analysis we evaluated the outcome of patients with pancreatic metastases ...
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9.
  • The role of mean corpuscula... The role of mean corpuscular volume and red cell distribution width in patients with metastatic renal cell carcinoma treated with tyrosine kinase inhibitors: the MARECAP retrospective study
    Tommasi, Chiara; Scartabellati, Giulia; Giannarelli, Diana ... Therapeutic advances in urology, 01/2023, Letnik: 15
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    Background: Tyrosine-kinase inhibitors (TKIs) and immunotherapy represent the backbone treatment for metastatic renal cell carcinoma (mRCC) patients. The aim of the present study was to describe mean ...
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10.
  • Inhibition of the VEGF/VEGFR pathway improves survival in advanced kidney cancer: a systematic review and meta-analysis
    Iacovelli, Roberto; Sternberg, Cora N; Porta, Camillo ... Current drug targets, 01/2015, Letnik: 16, Številka: 2
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    Despite the improvement in progression-free survival and response rates, none of the five anti- VEGF/VEGFR agents used for treatment of metastatic renal cell carcinoma (mRCC) reported a significant ...
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zadetkov: 165

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