Over the past 60 years, evidence has accumulated on the fundamental role of supportive social relationships in individual health and longevity. This paper first summarizes the results of 23 ...meta-analyses published between 1994 and 2021, which include 1,187 longitudinal and cross-sectional studies with more than 1,458 million participants. The effect sizes reported in these meta-analyses are highly consistent with regard to the predicted link between social support and reduced disease and mortality; the meta-analyses also highlight various theoretical and methodological issues concerning the multi-dimensionality of the social support concept and its measurements, and the need to control potential confounding and moderator variables. This is followed by an analysis of the experimental evidence from laboratory studies on psychobiological mechanisms that may explain the effect of social support on health and longevity. The stress-buffering hypothesis is examined and extended to incorporate recent findings on the inhibitory effect of social support figures (e.g., the face of loved ones) on fear learning and defensive reactions alongside evidence on the effect of social support on brain networks that down-regulate the autonomic nervous system, HPA axis, and immune system. Finally, the paper discusses the findings in the context of three emerging research areas that are helping to advance and consolidate the relevance of social factors for human health and longevity: (a) convergent evidence on the effects of social support and adversity in other social mammals, (b) longitudinal studies on the impact of social support and adversity across each stage of the human lifespan, and (c) studies that extend the social support framework from individual to community and societal levels, drawing implications for large-scale intervention policies to promote the culture of social support.
The neurovisceral integration model proposes a neuronal network that is related to heart rate activity and cognitive performance. The aim of this study was to determine whether heart rate variability ...(HRV) and variability in electroencephalographic (EEG) functional connectivity in the resting state are related to cognitive flexibility. Thirty-eight right-handed students completed the CAMBIOS test, and their heart and EEG activity was recorded during 6 min in the resting state with their eyes open. We calculated correlations, partial correlations and multiple linear regressions among HRV indices, functional brain connectivity variability and CAMBIOS scores. Furthermore, the sample was divided into groups according to CAMBIOS performance, and one-way ANOVA was applied to evaluate group differences. Our results show direct and inverse correlations among cognitive flexibility, connectivity (positive and negative task networks) and heartbeat variability. Partial correlations and multiple linear regressions suggest that the relation between HRV and CAMBIOS performance is mediated by neuronal oscillations. ANOVA confirms that HRV and variability in functional brain connectivity is related to cognitive performance. In conclusion, the levels of brain signal variability might predict cognitive flexibility in a cognitive task, while HRV might predict cognitive flexibility only when it is mediated by neuronal oscillations.
Research on the neural mechanisms of face identity constitutes a fruitful method to explore the affective contributions to face processing. Here, we investigated central and peripheral ...electrophysiological indices associated with the perception of loved faces. Subjects viewed black-and-white photographs of faces that belonged to one of five categories: loved ones, famous people, unknown people, babies, and neutral faces from the Eckman and Friesen system. Subcategories of loved faces included romantic partner, parents, siblings, second-degree relatives, and friends. Pictures were presented in two separate blocks, differing in viewing time (0.5s vs. 4s), inter-stimulus interval (1.2s vs. 18s), and number of face presentations (200 vs. 50). Heart rate, skin conductance, electromyography of the zygomatic muscle, and event-related potentials (ERPs) were obtained while participants passively viewed the pictures. Subjective picture ratings of valence, arousal, and dominance were obtained at the end of the experiment. Both central and peripheral electrophysiological measures differentiated faces of loved ones from all other categories by eliciting higher heart rate, skin conductance, and zygomatic activity, as well as larger amplitudes of the late ERP components P3 and LPP. Loved faces also resulted in higher valence and arousal, but lower dominance ratings. Additional differences were found among subcategories of loved faces. Faces of romantic partners elicited higher physiological (skin conductance and zygomatic activity) and subjective (emotional arousal) responses than parents, siblings, or friends, suggesting that looking at the image of someone we love evokes strong positive affect and emotional/cognitive arousal that go beyond a feeling of familiarity or simple recognition.
The neuroscientific study of love has been boosted by an extended corpus of research on face-identity recognition. However, few studies have compared the emotional mechanisms activated by loved faces ...and names and none have simultaneously examined fMRI and autonomic measures. The present study combined fMRI with the heart rate response when 21 participants (10 males) passively viewed the face or the written name of 4 loved people and 4 unknown people. The results showed accelerative patterns in heart rate, together with brain activations, which were significantly higher for loved people than for unknown people. Significant correlations were found between heart rate and brain activation in frontal areas, for faces, and in temporal areas, for names. The results are discussed in the context of previous studies using the same passive viewing procedure, highlighting the relevance of integrating peripheral and central measures in the scientific study of positive emotion and love.
For a large extent of historiography, the history of Spanish agriculture during the twentieth century is a story of success. However, this narrative has been built on monetary analysis, and it does ...not usually take into account the effects on rural society and agroecosystems. The aim of this paper is to analyze what has happened from a biophysical perspective to ascertain whether transformations linked with industrialization of agriculture have also been positive. For this, we have integrated the results—some unpublished and others already published—of a broader research project about different aspects of food production from a biophysical perspective in Spain, applying methodologies pertaining to the Social Metabolism. Our research seeks to provide a new narrative, emerging through the consideration of environmental aspects of the process, providing a more complex vision of the process of industrialization in European agriculture. The results show that the industrialization of Spanish agriculture has brought about profound changes in land uses and in the functionality of the biomass produced, increasing pressure on croplands and, paradoxically, facilitating the abandonment of an important proportion of pasture and croplands. This has led to the subordination of a very significant portion of Spanish agroecosystems to the feed demands of intensive livestock farming. This process has been based on the injection of large quantities of external energy. Agricultural production has undergone significant growth since the 1960s, but this has been insufficient to deal with the growing demand created by the change in the Spanish diet and the increasing trend to focus on livestock farming. The process of globalization has allowed both roles to be reconciled, although in recent decades Spain has accentuated its role as a net importer of biomass from a biophysical perspective, with very significant impacts on third party countries, particularly in Latin America. From a biophysical perspective, the industrialization of Spanish agriculture has entailed negative consequences that threaten the sustainability of Spanish agroecosystems and also negatively affect the sustainability of other territories.
A major problem in the electrophysiological studies of emotional processing linked to recognition of familiar faces is the unambiguous differentiation of effects due to emotional valence, arousal, ...and familiarity. The present paper summarizes a set of three studies aimed at investigating the affective processing of loved familiar faces using Lang's picture-viewing paradigm, with a special emphasis on teasing apart the individual contributions of affective valence, undifferentiated emotional arousal, and familiarity The results of the three studies support the conclusion that viewing the faces of familiar loved ones elicits an intense positive emotional reaction that cannot be explained either by familiarity or arousal alone.
► Viewing the faces of loved ones elicits large involuntary physiological responses. ► Photographs of loved familiar people are capable of inhibiting defensive reactions. ► The physiological responses to loved faces cannot be explained by familiarity.
The present study examined the effects of sustained anticipatory anxiety on the affective modulation of the eyeblink startle reflex. Towards this end, pleasant, neutral and unpleasant pictures were ...presented as a continuous stream during alternating threat-of-shock and safety periods, which were cued by colored picture frames. Orbicularis-EMG to auditory startle probes and electrodermal activity were recorded. Previous findings regarding affective picture valence and threat-of-shock modulation were replicated. Of main interest, anticipating aversive events and viewing affective pictures additively modulated defensive activation. Specifically, despite overall potentiated startle blink magnitude in threat-of-shock conditions, the startle reflex remained sensitive to hedonic picture valence. Finally, skin conductance level revealed sustained sympathetic activation throughout the entire experiment during threat- compared to safety-periods. Overall, defensive activation by physical threat appears to operate independently from reflex modulation by picture media. The present data confirms the importance of simultaneously manipulating phasic-fear and sustained-anxiety in studying both normal and abnormal anxiety.
Among defensive behaviors, tonic immobility (TI) is considered the last defensive resort when life is at extreme risk. Post-Traumatic Stress Disorder (PTSD) is the main psychiatric consequence ...resulting from exposure to traumatic events. Increasing evidence indicate an association between peritraumatic tonic immobilility and severity of PTSD. Cardiac defense response, a reactivity to perceived danger or threat, has been studied by recording heart rate changes that follows the presentation of an unpredictable intense auditory aversive stimulus. The aim of this study was to investigate potential distinctiveness in cardiac defense response among PTSD patients who presented - compared to those that did not - TI reaction in the laboratory setting. Patients (
= 17) completed the TI questionnaire for signs of immobility elicited by passive listening to their autobiographical trauma script. After a while, they were exposed to an intense white noise, while electrocardiogram was recorded. The heart rate during the 80 s after the noise, subtracted from baseline, was analyzed. Higher reports of TI to the trauma script were associated with stronger and sustained heart rate accelerations after the noise. The effects on cardiac defense response add to increasing evidence that some PTSD patients are prone to repeated re-experiences of TI, which may implicate in a potentially distinct pathophysiology and even a new PTSD subtype.
The way our brain processes personal familiarity is still debatable. We used searchlight multivoxel pattern analysis (MVPA) to identify areas where local fMRI patterns could contribute to familiarity ...detection for both faces and name categories. Significantly, we identified cortical areas in frontal, temporal, cingulate, and insular areas, where it is possible to accurately cross-classify familiar stimuli from one category using a classifier trained with the stimulus from the other (i.e., abstract familiarity) based on local fMRI patterns. We also discovered several areas in the fusiform gyrus, frontal, and temporal regions-primarily lateralized to the right hemisphere-supporting the classification of familiar faces but failing to do so for names. Also, responses to familiar names (compared to unfamiliar names) consistently showed less activation strength than responses to familiar faces (compared to unfamiliar faces). The results evinced a set of abstract familiarity areas (independent of the stimulus type) and regions specifically related only to face familiarity, contributing to recognizing familiar individuals.
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