Measurements of present‐day surface deformation are essential for the assessment of long‐term seismic hazard. The European Space Agency's Sentinel‐1 satellites enable global, high‐resolution ...observation of crustal motion from Interferometric Synthetic Aperture Radar (InSAR). We have developed automated InSAR processing systems that exploit the first ~5 years of Sentinel‐1 data to measure surface motions for the ~800,000‐km2 Anatolian region. Our new 3‐D velocity and strain rate fields illuminate deformation patterns dominated by westward motion of Anatolia relative to Eurasia, localized strain accumulation along the North and East Anatolian Faults, and rapid vertical signals associated with anthropogenic activities and to a lesser extent extension across the grabens of western Anatolia. We show that automatically processed Sentinel‐1 InSAR data can characterize details of the velocity and strain rate fields with high resolution and accuracy over large regions. These results are important for assessing the relationship between strain accumulation and release in earthquakes.
Plain Language Summary
Satellite‐based measurements of small rates of motion of the Earth's surface made at high spatial resolutions and over large areas are important for many geophysical applications including improving earthquake hazard models. We take advantage of recent advances in geodetic techniques in order to measure surface velocities and tectonic strain accumulation across the Anatolia region, including the highly seismogenic and often deadly North Anatolian Fault. We show that by combining Sentinel‐1 Interferometric Synthetic Aperture Radar (InSAR) data with Global Navigation Satellite System (GNSS) measurements we can enhance our view of surface deformation associated with active tectonics, the earthquake cycle, and anthropogenic processes.
Key Points
We produce high‐resolution horizontal and vertical velocity and strain rate fields for Anatolia from Sentinel‐1 InSAR and GNSS observations
Velocity gradients indicate shear strain accumulation along the North and East Anatolian Faults and extension across western Anatolia
InSAR data are critical for capturing high‐resolution details of the velocity and strain rate fields
Space-borne Synthetic Aperture Radar (SAR) Interferometry (InSAR) is now a key geophysical tool for surface deformation studies. The European Commission’s Sentinel-1 Constellation began acquiring ...data systematically in late 2014. The data, which are free and open access, have global coverage at moderate resolution with a 6 or 12-day revisit, enabling researchers to investigate large-scale surface deformation systematically through time. However, full exploitation of the potential of Sentinel-1 requires specific processing approaches as well as the efficient use of modern computing and data storage facilities. Here we present Looking Into Continents from Space with Synthetic Aperture Radar (LiCSAR), an operational system built for large-scale interferometric processing of Sentinel-1 data. LiCSAR is designed to automatically produce geocoded wrapped and unwrapped interferograms and coherence estimates, for large regions, at 0.001° resolution (WGS-84 coordinate system). The products are continuously updated at a frequency depending on prioritised regions (monthly, weekly or live update strategy). The products are open and freely accessible and downloadable through an online portal. We describe the algorithms, processing, and storage solutions implemented in LiCSAR, and show several case studies that use LiCSAR products to measure tectonic and volcanic deformation. We aim to accelerate the uptake of InSAR data by researchers as well as non-expert users by mass producing interferograms and derived products.
Earthquakes are caused by the release of tectonic strain accumulated between events. Recent advances in satellite geodesy mean we can now measure this interseismic strain accumulation with a high ...degree of accuracy. But it remains unclear how to interpret short-term geodetic observations, measured over decades, when estimating the seismic hazard of faults accumulating strain over centuries. Here, we show that strain accumulation rates calculated from geodetic measurements around a major transform fault are constant for its entire 250-year interseismic period, except in the ~10 years following an earthquake. The shear strain rate history requires a weak fault zone embedded within a strong lower crust with viscosity greater than ~10
Pa s. The results support the notion that short-term geodetic observations can directly contribute to long-term seismic hazard assessment and suggest that lower-crustal viscosities derived from postseismic studies are not representative of the lower crust at all spatial and temporal scales.
Interest in the cerebellum is expanding given evidence of its contributions to cognition and emotion, and dysfunction in various psychopathologies. However, research into its genetic architecture and ...shared influences with liability for mental disorders is lacking. We conducted a genome-wide association study (GWAS) of total cerebellar volume and underlying cerebellar lobe volumes in 33,265 UK-Biobank participants. Total cerebellar volume was heritable (h
= 50.6%), showing moderate genetic homogeneity across lobes (h
from 35.4% to 57.1%; mean genetic correlation between lobes r
≈ 0.44). We identified 33 GWAS signals associated with total cerebellar volume, of which 6 are known to alter protein-coding gene structure, while a further five mapped to genomic regions known to alter cerebellar tissue gene expression. Use of summary data-based Mendelian randomisation further prioritised genes whose change in expression appears to mediate the SNP-trait association. In total, we highlight 21 unique genes of greatest interest for follow-up analyses. Using LD-regression, we report significant genetic correlations between total cerebellar volume and brainstem, pallidum and thalamus volumes. While the same approach did not result in significant correlations with psychiatric phenotypes, we report enrichment of schizophrenia, bipolar disorder and autism spectrum disorder associated signals within total cerebellar GWAS results via conditional and conjunctional-FDR analysis. Via these methods and GWAS catalogue, we identify which of our cerebellar genomic regions also associate with psychiatric traits. Our results provide important insights into the common allele architecture of cerebellar volume and its overlap with other brain volumes and psychiatric phenotypes.
Adaptation in new environments depends on the amount of genetic variation available for evolution, and the efficacy by which natural selection discriminates among this variation. However, whether ...some ecological factors reveal more genetic variation, or impose stronger selection pressures than others, is typically not known. Here, we apply the enzyme kinetic theory to show that rising global temperatures are predicted to intensify natural selection throughout the genome by increasing the effects of DNA sequence variation on protein stability. We test this prediction by (i) estimating temperature-dependent fitness effects of induced mutations in seed beetles adapted to ancestral or elevated temperature, and (ii) calculate 100 paired selection estimates on mutations in benign versus stressful environments from unicellular and multicellular organisms. Environmental stress
did not increase mean selection on de novo mutation, suggesting that the cost of adaptation does not generally increase in new ecological settings to which the organism is maladapted. However, elevated temperature increased the mean strength of selection on genome-wide polymorphism, signified by increases in both mutation load and mutational variance in fitness. These results have important implications for genetic diversity gradients and the rate and repeatability of evolution under climate change.
Abstract
The temporal evolution of slip on surface ruptures during an earthquake is important for assessing fault displacement, defining seismic hazard and for predicting ground motion. However, ...measurements of near-field surface displacement at high temporal resolution are elusive. We present a novel record of near-field co-seismic displacement, measured with 1-second temporal resolution during the 30
th
October 2016 M
w
6.6 Vettore earthquake (Central Italy), using low-cost Global Navigation Satellite System (GNSS) receivers located in the footwall and hangingwall of the Mt. Vettore - Mt. Bove fault system, close to new surface ruptures. We observe a clear temporal and spatial link between our near-field record and InSAR, far-field GPS data, regional measurements from the Italian Strong Motion and National Seismic networks, and field measurements of surface ruptures. Comparison of these datasets illustrates that the observed surface ruptures are the propagation of slip from depth on a surface rupturing (i.e. capable) fault array, as a direct and immediate response to the 30
th
October earthquake. Large near-field displacement ceased within 6–8 seconds of the origin time, implying that shaking induced gravitational processes were not the primary driving mechanism. We demonstrate that low-cost GNSS is an accurate monitoring tool when installed as custom-made, short-baseline networks.
Research and clinical translation in schizophrenia is limited by inconsistent definitions of treatment resistance and response. To address this issue, the authors evaluated current approaches and ...then developed consensus criteria and guidelines.
A systematic review of randomized antipsychotic clinical trials in treatment-resistant schizophrenia was performed, and definitions of treatment resistance were extracted. Subsequently, consensus operationalized criteria were developed through 1) a multiphase, mixed methods approach, 2) identification of key criteria via an online survey, and 3) meetings to achieve consensus.
Of 2,808 studies identified, 42 met inclusion criteria. Of these, 21 studies (50%) did not provide operationalized criteria. In the remaining studies, criteria varied considerably, particularly regarding symptom severity, prior treatment duration, and antipsychotic dosage thresholds; only two studies (5%) utilized the same criteria. The consensus group identified minimum and optimal criteria, employing the following principles: 1) current symptoms of a minimum duration and severity determined by a standardized rating scale; 2) moderate or worse functional impairment; 3) prior treatment consisting of at least two different antipsychotic trials, each for a minimum duration and dosage; 4) systematic monitoring of adherence and meeting of minimum adherence criteria; 5) ideally at least one prospective treatment trial; and 6) criteria that clearly separate responsive from treatment-resistant patients.
There is considerable variation in current approaches to defining treatment resistance in schizophrenia. The authors present consensus guidelines that operationalize criteria for determining and reporting treatment resistance, adequate treatment, and treatment response, providing a benchmark for research and clinical translation.
An InSAR‐GNSS Velocity Field for Iran Watson, Andrew R.; Elliott, John R.; Lazecký, Milan ...
Geophysical research letters,
28 May 2024, Letnik:
51, Številka:
10
Journal Article
Recenzirano
Odprti dostop
We present average ground‐surface velocities and strain rates for the 1.7 million km2 area of Iran, from the joint inversion of InSAR‐derived displacements and GNSS data. We generate interferograms ...from 7 years of Sentinel‐1 radar acquisitions, correct for tropospheric noise using the GACOS system, estimate average velocities using LiCSBAS time‐series analysis, tie this into a Eurasia‐fixed reference frame, and perform a decomposition to estimate East and Vertical velocities at 500 m spacing. Our InSAR‐GNSS velocity fields reveal predominantly diffuse crustal deformation, with localized interseismic strain accumulation along the North Tabriz, Main Kopet Dagh, Main Recent, Sharoud, and Doruneh faults. We observe signals associated with recent groundwater subsidence, co‐ and postseismic deformation, active salt diaprism, and sediment motion. We derive high‐resolution strain rate estimates on a country‐ and fault‐scale, and discuss the difficulties of mapping diffuse strain rates in areas with abundant non‐tectonic and anthropogenic signals.
Plain Language Summary
Across the entire country of Iran, the ongoing convergence of the Arabian and Eurasian tectonic plates at about two cm every year is deforming the Earth's crust, producing earthquakes in this process of continental collision. Accurate measurements of how the ground is moving today are critical to understanding both the county‐scale deformation, and the local‐scale earthquake hazard, where the crust is deforming quickly and building up strain that is likely to be released in future major earthquakes. We combine multiple series of satellite radar images with GPS velocities to estimate East and vertical ground motion across all of Iran, at a higher level of detail than previous GPS‐only studies have been able to capture. Our velocity fields show a complex mix of ground motion signals, from crustal deformation on a country‐scale, to rapid land subsidence caused by the extraction of groundwater from aquifers. Some of the major faults are clearly building up strain for future earthquakes, but other regions are deforming much more diffusely, making it difficult to ascertain the locations of any future seismic hazard and ground shaking.
Key Points
We generate high‐resolution East and vertical velocity fields for Iran using Sentinel‐1 InSAR and GNSS observations
Regional deformation is diffuse, with interseismic strain localized onto the Doruneh, Main Kopet Dagh, North Tabriz, and Sharoud faults
Iran contains a wealth of time‐varying, short‐wavelength signals associated with groundwater extraction, salt diaprism, and sediment motion
Following earthquakes, faults are often observed to continue slipping aseismically. It has been proposed that this afterslip occurs on parts of the fault with rate‐strengthening friction that are ...stressed by the main shock, but our understanding has been limited by a lack of immediate, high‐resolution observations. Here we show that the behavior of afterslip following the 2014 South Napa earthquake in California varied over distances of only a few kilometers. This variability cannot be explained by coseismic stress changes alone. We present daily positions from continuous and survey GPS sites that we remeasured within 12 h of the main shock and surface displacements from the new Sentinel‐1 radar mission. This unique geodetic data set constrains the distribution and evolution of coseismic and postseismic fault slip with exceptional resolution in space and time. We suggest that the observed heterogeneity in behavior is caused by lithological controls on the frictional properties of the fault plane.
Key Points
Small‐scale spatial and temporal variability of modes of slip observed geodetically
Afterslip is delimited by variations in lithology more than Coulomb stress changes
Addition of postseismic contribution increases moment budget by 30%
The ability to rapidly access optical satellite imagery is now an intrinsic component of managing the disaster response that follows a major earthquake. These images provide synoptic data on the ...impacts, extent, and intensity of damage, which is essential for mitigating further losses by feeding into the response coordination. However, whilst the efficiency of the response can be hampered when cloud cover limits image availability, spatio-temporal variations in cloud cover have never been considered as part of the design of effective disaster mapping. Here we show how annual variations in cloud cover may affect our capacity to respond rapidly throughout the year and consequently contribute to overall earthquake risk. We find that on a global scale when accounting for cloud, the worst time of year for an earthquake disaster is between June and August. During these months, 40% of the global population at risk from earthquakes are obscured from optical satellite view for >3 consecutive days. Southeastern Asia is particularly strongly affected, accounting for the majority of the population at risk from earthquakes that could be obscured by cloud in every month. Our results demonstrate the importance of the timing of earthquakes in terms of our capacity to respond effectively, highlighting the need for more intelligent design of disaster response that is not overly reliant on optical satellite imagery.
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