The passive stiffness and strength of periscapular muscles may affect scapulohumeral control, especially in overhead athletes due to sports-specific training. This study tried to assess the ...relationship between the passive stiffness and strength of periscapular muscles, scapulohumeral kinematics and neuromuscular control during scaption in swimmers. Ten male adolescent competitive front-crawl swimmers were recruited. The passive stiffness and strength of periscapular muscles were measured in standard postures by a hand-held myotonometer and dynamometer, respectively. Surface electromyography and electromagnetic tracking systems were synchronized to record the muscle activities and scapulohumeral kinematics during scaption. Correlations between the passive stiffness or strength of periscapular muscles and the kinematics or muscle activity were examined by Spearman's rank correlation coefficient. The maximal strength of periscapular muscles correlated positively with the ranges of upward and external rotation of the scapula and negatively with muscle activity during scaption. Passive stiffness of periscapular muscles was associated with the downward rotation of the scapula and triggered an increase in muscle activity. Increased passive stiffness or decreased strength in the periscapular muscles may affect their role in controlling the scapular rotation and contribute to compensation from adjacent muscles. Our findings suggest that when attempting to evaluate scapular behavior, it may be beneficial to examine muscle strength and passive stiffness of periscapular muscles.
Autologous vascular grafts have the advantages of better biocompatibility and prognosis. However, previous studies that implanted bare polymer tubes in animals to grow autologous tubular tissues were ...limited by their poor yield rates and stability. To enhance the yield rate of the tubular tissue, we employed a design with the addition of overlaid autologous whole blood scaffold containing lipopolysaccharides (LPS). Furthermore, we applied in vivo dynamic mechanical stimuli through cyclically inflatable silicone tube to improve the mechanical properties of the harvested tissues. The effectiveness of the modification was examined by implanting the tubes in the peritoneal cavity of rats. A group without mechanical stimuli served as the controls. After 24 days of culture including 16 days of cyclic mechanical stimuli, we harvested the tubular tissue forming on the silicone tube for analysis or further autologous interposition vascular grafting. In comparison with those without cyclic dynamic stimuli, tubular tissues with this treatment during in vivo culture had stronger mechanical properties, better smooth muscle differentiation, and more collagen and elastin expression by the end of incubation period in the peritoneal cavity. The grafts remained patent after 4 months of implantation and showed the presence of endothelial and smooth muscle cells. This model shows a new prospect for vascular tissue engineering.
We synthesized a biodegradable, elastomeric, and functionalizable polyurethane (PU) that can be electrospun for use as a scaffold in soft tissue engineering. The PU was synthesized from ...polycaprolactone diol, hexamethylene diisocyanate, and dimethylolpropionic acid (DMPA) chain extender using two-step polymerization and designated as PU-DMPA. A control PU using 1,4-butanediol (1,4-BDO) as a chain extender was synthesized similarly and designated as PU-BDO. The chemical structure of the two PUs was verified by FT-IR and 1H-NMR. The PU-DMPA had a lower molecular weight than the PU-BDO (~16,700 Da vs. ~78,600 Da). The melting enthalpy of the PU-DMPA was greater than that of the PU-BDO. Both the PUs exhibited elastomeric behaviors with a comparable elongation at break (λ=L/L0= 13.2). The PU-DMPA had a higher initial modulus (19.8 MPa vs. 8.7 MPa) and a lower linear modulus (0.7 MPa vs. 1.2 MPa) and ultimate strength (9.5 MPa vs. 13.8 MPa) than the PU-BDO. The PU-DMPA had better hydrophilicity than the PU-BDO. Both the PUs displayed no cytotoxicity, although the adhesion of human umbilical artery smooth muscle cells on the PU-DMPA surface was better. Bead free electrospun PU-DMPA membranes with a narrow fiber diameter distribution were successfully fabricated. As a demonstration of its functionalizability, gelatin was conjugated to the electrospun PU-DMPA membrane using carbodiimide chemistry. Moreover, hyaluronic acid was immobilized on the amino-functionalized PU-DMPA. In conclusion, the PU-DMPA has the potential to be used as a scaffold material for soft tissue engineering.
Space and spatiality in theory Merriman, Peter; Jones, Martin; Olsson, Gunnar ...
Dialogues in human geography,
03/2012, Letnik:
2, Številka:
1
Journal Article
Recenzirano
This article is an edited transcript of a panel discussion on ‘Space and Spatiality in Theory’ which was held at the Annual Meeting of the Association of American Geographers, Washington, DC, April ...2010. In the article, the panel map out some of the challenges for thinking, writing and performing spaces in the 21st century, reflecting upon the emergence of new ways of theorizing space and spatiality, the relationship between writing, action and spacing, and the emergence of distinctive spatialized ontologies (e.g. ‘movement-space’) which appear to reflect epistemological and technological shifts in how our worlds are thought, produced and inhabited. The panellists stress the importance of recognizing the partial nature of Anglophone theoretical approaches, and they argue for more situated and modest theories. They also reflect upon the importance of a wide range of disciplinary knowledges and practices to their thinking on the spatialities of the world, from philosophy and the natural sciences to art and poetry.
Spoken content processing (such as retrieval and browsing) is maturing, but the singing content is still almost completely left out. Songs are human voice carrying plenty of semantic information just ...as speech, and may be considered as a special type of speech with highly flexible prosody. The various problems in song audio, for example the significantly changing phone duration over highly flexible pitch contours, make the recognition of lyrics from song audio much more difficult. This paper reports an initial attempt towards this goal. We collected music-removed version of English songs directly from commercial singing content. The best results were obtained by TDNN-BLSTM with data augmentation with 3-fold speed perturbation plus some special approaches. The WER achieved (73.90%) was significantly lower than the baseline (96.21 %), but still relatively high.
Adipose stromal vascular fraction (SVF) has a versatile cellular system for biologically augmented therapies. However, there have been no clinical studies investigating the benefits of the ...augmentation of anterior cruciate ligament reconstruction (ACLR) with SVF. We conducted a retrospective study in assessing the effects of intraoperative SVF administration on the functional outcomes in young patients with ACLR. The enrolled patients were divided into the control group (ACLR only) and the SVF group (ACLR with SVF). The functional outcomes in both groups were assessed by the Lysholm knee scoring system, the Tegner activity scale, and the International Knee Documentation Committee (IKDC) subjective evaluation form, and compared at several time points during a 12-month follow-up. We found that the sex distribution and pre-surgery scores were similar in the two groups, whereas the mean age of the SVF group was higher than that of the control group (p = 0.046). The between-group analysis and generalized estimating equation model analysis revealed that, while patients in the SVF group significantly improved all their functional outcomes at 12 months after surgery, this improvement was not significantly different from the results of patients in the control group (Lysholm, p = 0.553; Tegner, p = 0.197; IKDC, p = 0.486). No side effects were observed in either group. We concluded that the intraoperative administration of SVF does not improve or accelerate functional recovery after ACLR in young patients.
Polyimides (PI) synthesized from 4,4′‐(hexafluoroisopropylidene)diphthalic anhydride (6FDA) with various diamines have been frequently studied as gas separation membranes. The use of 6FDA in ...polyimides creates a bent structure than can increase fractional free volume (FFV) and gas permeability. Here, we demonstrate that 6FDA is also a useful building block for PI‐ionene materials, which contain cations directly within the polymer backbone. These new 6FDA‐containing PI‐ionenes were combined with several different imidazolium ionic liquids (ILs) to form thin membranes. The thermal properties of all the derivatives were investigated to determine the relationship between regiochemistry and degradation as well as the intermolecular forces that are present within these structures. The gas separation properties of these 6FDA‐containing PI‐ionene + IL materials were investigated, showing modest CO2 permeabilities similar to other polyimide‐ionenes and CO2/CH4 and CO2/N2 permselectivities that were relatively higher than other polyimide‐ionenes.
The synthesis of polyimide membranes for energy‐efficient gas separations typically relies on the reaction of a dianhydride with a diamine. Although effective, this conventional approach limits the number of potential structures and compositions available to study. However, 6FDA‐containing polyimide‐ionenes and composites with ionic liquids open vast new opportunities in the design of polymer gas‐separation membranes for applications such as the removal of CO2 from industrial processes.
ABSTRACT
We propose a compact binary model with an eccentric orbit to explain periodically active fast radio burst (FRB) sources, where the system consists of a neutron star (NS) with strong dipolar ...magnetic fields and a magnetic white dwarf (WD). In our model, the WD fills its Roche lobe at periastron, and mass transfer occurs from the WD to the NS around this point. The accreted material may be fragmented into a number of parts, which arrive at the NS at different times. The fragmented magnetized material may trigger magnetic reconnection near the NS surface. The electrons can be accelerated to an ultrarelativistic speed, and therefore the curvature radiation of the electrons can account for the burst activity. In this scenario, the duty cycle of burst activity is related to the orbital period of the binary. We show that such a model may work for duty cycles roughly from 10 min to 2 d. For the recently reported 16.35-d periodicity of FRB 180916.J0158 + 65, our model does not naturally explain such a long duty cycle, since an extremely high eccentricity (e > 0.95) is required.
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