The work is focused on combined transport in the Czech Republic and abroad. The theoretical part contains basic information about combined transport, as well as the combined transport in the CR, the ...most important terminals and information on individual subjects in combined transport. The work discusses the different development of combined transport both at home and in Germany. The next section discussed the problem of international combined transport and of course the positive aspects of its use. Conclusion of the theoretical part contains trend of combined transport and impact of the financial crisis. The practical part contains model calculation of the return on investment to swap bodies and demonstate the benefits of investment.
Presented master thesis deals with description of the gradual development and positions of the church schools in CR during the last 20 years. These schools are then complemented by the schools of ...theology at CR universities. This thesis is in a certain way a continuation of a bachelor thesis, successfully defended in 2007 at the School of Education of Charles University. The thesis describes in brief the history of education and pedagogy in general, church schools including. Then there are specified all the pertinent valid legal regulations for operation of church schools based on experience of the author from a managerial position of such a school for many years. The role of the general management and management of human resources on one side and the theological reflection of the church schools on the other side is discussed. In detail, the equipment of the facilities and their economy is analyzed as well as the goals and calling of these schools. In a wide spectrum of opportunities open to church schools in 21st century their potential can be used through new and fresh methods for evangelizing, mission and pastoral care.
The subject of this diploma thesis is to analyse the development of public debt in the Czech Republic between years 1993 and 2014. The text is divided into two main parts, the section about ...theoretical basis of this topic and the section which contains practical knowledge about specific aspects of the Czech public sector. The theoretical part briefly defines basic terms and facts of the public debt, such as public sector, budgetary system and public debt classification. The second part focuses on real-life functioning of the Czech public sector, so there are introduced Czech budgetary system and budget process and various methodological frameworks for debt analyses. The final and most significant part of the thesis deals with the real values of state, municipality and government indebtedness, emphasis is placed on the development trends.
In the theoretical part of my graduation theses I occupy myself with the questions of the social climate of the class and with the alternative education, its history, function and its connection with ...the quality of social climate of classes, which are directed by the given style of education. The research part results from the investigation done at four types of school, which are working by different School education programs, finding out the social climate of the classes at this schools and searching connections between the climate of the classes and the pedagogical ideas, from which the school education program results.
Tato diplomová práce pojednává o ochraně osobních údajů. Osobní údaje jsou velice citlivým tématem, které se dotýká každého z nás. Teoretická část objasňuje některé základní pojmy nově přijatého ...zákona o ochraně osobních údajů, který upravuje tuto problematiku. Pozornost je taktéž věnována výkladu samotného zákona a nově vzniklé instituce Úřadu pro ochranu osobních údajů.Praktická část je zaměřena na aplikaci získaných poznatků z teorie na konkrétní příspěvkovou organizaci Nemocnice Jihlava. Osobní údaje zpracovává zdravotnické zařízení v době od přijetí pacienta, po celou dobu léčby a v malé míře i po ní. Tato praktická část diplomové práce se především zabývá povinnostmi zaměstnanců příspěvkové organizace Nemocnice Jihlava při vedení zdravotnické dokumentace a právy občanů a pacientů v oblasti ochrany osobních údajů v tomto zdravotnickém zařízení.
Provider: Czech digital library/Česká digitální knihovna - Institution: National Medical Library/Národní lékařská knihovna - Data provided by Europeana Collections- Cíl: Cílem této pilotní studie byl ...celogenomový screening metylace DNA u pacientek s nádory ovarií. Sledování metylace bylo zaměřeno jak do promotorových oblastí vybraných genů, tak do ostrůvků bohatých na CpG. Typ studie: Pilotní studie. Materiál a metody: Do studie bylo zařazeno šest vzorků získaných od pacientek s nově diagnostikovaným ovariálním karci - nomem a šest vzorků nenádorových ovárií. Vzorky byly analyzovány pomocí zákazníkem navržených metylačních mikročipů založených na metylované-DNA imunoprecipitaci. Výsledky: Pomocí mikročipů navržených ve spolupráci se specialisty firmy HPST se nám podařilo poukázat u nádorové tká - ně na tendenci k celkové hypometylaci DNA. Dále se nám podařilo získat soubor hypermetylovaných genů ke konfirmačním analýzám. Závěr: Vzhledem k tomu, že změny v metylaci DNA jsou jedním z prvních projevů v průběhu karcinogeneze, mohly by být nalezené změny, v případě jejich průkazu v plazmě pacientek, v budoucnu využity jako screeningové markery u rizikové populace. Monitorování metylace DNA by mohlo přispět ke zlepšení péče o nemocné s ovariálním karcinomem, včetně možné finanční úspory díky včasné diagnóze a případné predikci odpovědi na léčbu- Objective: The aim of this pilot study was whole-genome screening of DNA methylation in ovarian cancer patients. Monito - ring of DNA methylation was focused on promoter regions and also on CpG islands. Design: Pilot study Material and methods: Our study included 6 samples obtained from patients with newly diagnosed ovarian cancer and 6 nonmalignant control samples of ovaries. All samples were analysed using a custom designed methylation microarrays based on the methylated DNA immunoprecipitation. Results: Using microarrays designed in collaboration with specialists of the HPST company we found in the tumor tissue tendency to overall DNA hypomethylation. Furthermore we managed to get a set of hypermethylated genes for confirmation analyses. Conclusion: DNA methylation changes are considered to be a one of the first changes during carcinogenesis. Due to this fact could be newly identified changes, in case of detection in plasma of ovarian cancer patient, used as screening markers in risk population. Monitoring of DNA methylation could contribute to improve the care of ovarian cancer patients, including possible financial saving due to early diagnosis and possible prediction of response to treatment.- Chmelařová M., Ruszová E., Laco J., Dvořáková E., Smetana J., Hrochová K., Palička V.- Literatura- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
