Liposomes play a significant role in encapsulation of various bioactive compounds (BACs), including functional food ingredients to improve the stability of core. This technology can be used for ...promoting an effective application in functional food and nutraceuticals. Incorporation of traditional and emerging methods for the developments of liposome for loading BACs resulted in viable and stable liposome formulations for industrial applications. Thus, the advance technologies such as supercritical fluidic methods, microfluidization, ultrasonication with traditional methods are revisited. Liposomes loaded with plant and animal BACs have been introduced for functional food and nutraceutical applications. In general, application of liposome systems improves stability, delivery, and bioavailability of BACs in functional food systems and nutraceuticals. This review covers the current techniques and methodologies developed and practiced in liposomal preparation and application in functional foods.
In addition to their pigment properties, the potential health benefits of anthocyanins have made them a subject of interest in recent years. This study aimed to obtain purified anthocyanin fractions ...from native Mexican black bean cultivars using Amberlite XAD-7 resin column and HPCCC and evaluate their anti-inflammatory properties using RAW 264.7 cells. The major anthocyanins in the purified anthocyanin fractions were delphinidin 3-glucoside (61.8%), petunidin 3-glucoside (25.2%), and malvidin 3-glucoside (12.2%). Purified anthocyanin fractions at 12.5 μg/mL effectively prevented LPS-induced ERK1/ERK2 phosphorylation and reduced the protein expression of COX-2 and mRNA expression of iNOS. Results showed that purified anthocyanin fractions have the potential to modulate the inflammatory response by inhibiting the production of pro-inflammatory mediators through the ERK1/ERK2 and NF-κB pathways. This study suggests that anthocyanins from black beans could be used as a natural strategy to help modulate inflammation-associated diseases.
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•Native bean anthocyanins could be used as a strategy to control inflammation.•Purified anthocyanin fractions from black beans were effectively obtained by HPCCC.•Black bean anthocyanins modulate inflammation through the ERK and NF-κB pathways.
•Secondary metabolites are used in pharmaceutical industries, cosmetics, dietary supplements, fragrances, flavors, dyes, etc.•Metabolic engineering is an important biological tool to produce ...commercially importance metabolites.•The biosynthetic pathways for production of secondary metabolites in plants are derived from the shikimate, terpenoid, and polyketide pathways.•A huge number of medicinal plants and their metabolites have been produced by in vitro techniques.
Plants have been used throughout the world for its medicinal powers since ancient time. The pharmacological properties of plants are based on their phytochemical components especially the secondary metabolites which are outstanding sources of value added bioactive compounds. Secondary metabolites have complex chemical composition and are produced in response to various forms of stress to perform different physiological tasks in plants. They are used in pharmaceutical industries, cosmetics, dietary supplements, fragrances, flavors, dyes, etc. Extended use of these metabolites in various industrial sectors has initiated a need to focus research on increasing the production by employing plant tissue culture (PTC) techniques and optimizing their large scale production using bioreactors. PTC techniques being independent of climatic and geographical conditions will provide an incessant, sustainable, economical and viable production of secondary metabolites. This review article intends to assess the advantages of using plant tissue culture, distribution of important secondary metabolites in plant families, strategies involved for optimal metabolite production and the industrial importance of selected secondary metabolites.
Knowledge of rice's nutritional value and health benefits is essential to increase rice consumption in people's daily diet. Rice is known as a queen of cereal crops that have a high nutritional value ...such as carbohydrate, fat, fiber, protein, vitamins as well as food energy, minerals profile and fatty acids.
The present review paper mainly focuses on the chemistry of rice bioactive compounds, methods of extraction, identification, and characterization as well as biological activities and health benefits.
The nutritional components are found in various types of rice which grown and utilized by farmers and consumers respectively with more than 60% population worldwide. In addition to nutritional components, there are many phytochemicals present in rice have been identified as bioactive compounds which have their many high biological activities, in which antioxidant, anticancer, antidiabetic and antiinflammation activities are major one, as other cereals have and also exhibit their potential beneficial health effects in human as they all consume rice in their daily routine diet.
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•Extracts of pigmented and non-pigmented rice contain various bioactive compounds (BACs).•Solvent extraction is the most common conventional method used to extract BACs from rice.•HPLC is the most frequently used analytical method to identify and characterize rice BACs.•Biologically active phytochemicals in rice prevent many chronic human diseases.•These BACs are creating new interests for industrial use in food and nutraceutical products.
Bone is a highly integrative and dynamic tissue of the human body. It is continually remodeled by bone cells such as osteoblasts, osteoclasts. When a fraction of a bone is damaged or deformed, stem ...cells and bone cells under the influence of several signaling pathways regulate bone regeneration at the particular locale. Effective therapies for bone defects can be met via bone tissue engineering which employs drug delivery systems with biomaterials to enhance cellular functions by acting on signaling pathways such as Wnt, BMP, TGF-β, and Notch. This review provides the current understanding of polymers/bioceramics/bioactive compounds as scaffolds in activation of signaling pathways for the formation of bone.
This work reviews applications of high added value molecules produced from microalgae. Older forms of valorization - health food and quality feed, polyunsaturated fatty acids, pigments, carbohydrates ...- are currently penetrating their markets. They are driven by desirable properties: texturer and dye for food industry, antioxidant for cosmetics and the appetite of the general public for biosourced compounds. Most recent developments, such as peptides, vitamins, polyphenols, phytosterols and phytohormones, are struggling to meet their market and reach economical competitiveness. Still they are pushed forward by the very powerful driver that is pharmaceutical industry. In addition this work also proposes to link microalgae phyla and related potential applications. This is done through highlighting of which bioactive compounds can be found in which phyla. While some seem to be restricted to aquaculture, Cyanobacteria, Chlorophyta and Rhodophyta show great promises.