The Accepted Article version of the above article, published online on 25 May 2021 in Wiley Online Library (wileyonlinelibrary.com), has been withdrawn by agreement between the corresponding author, ...the journal′s Executive Committee, and Wiley‐VCH GmbH, Weinheim. The withdrawal has been agreed upon due to significant conceptual similarities with another of the authors' recently published articles, which was not disclosed during the peer review process.
Fernando P. Cossío
European journal of organic chemistry,
November 25, 2018, Letnik:
2018, Številka:
43
Journal Article
Recenzirano
“Our aim is to discover unexpected phenomena and emergent properties from unusual catalysts involving different types of chirality.” Find out more about this author's research at ...https://doi.org/10.1002/ejoc.201800911.
“Our aim is to discover unexpected phenomena and emergent properties from unusual catalysts involving different types of chirality.” Find out more about this author's research at https://doi.org/10.1002/ejoc.201800911.
With the rapid development of asymmetric catalysis, the demand for the enantioselective synthesis of complex and diverse molecules with different chiral elements is increasing. Owing to the unique ...features of atropisomerism, the catalytic asymmetric synthesis of atropisomers has attracted a considerable interest from the chemical science community. In particular, introducing additional chiral elements, such as carbon centered chirality, heteroatomic chirality, planar chirality, and helical chirality, into atropisomers provides an opportunity to incorporate new properties into axially chiral compounds, thus expanding the potential applications of atropisomers. Thus, it is important to perform catalytic asymmetric transformations to synthesize atropisomers bearing multiple chiral elements. In spite of challenges in such transformations, in recent years, chemists have devised powerful strategies under asymmetric organocatalysis or metal catalysis, synthesizing a wide range of enantioenriched atropisomers bearing multiple chiral elements. Therefore, the catalytic asymmetric synthesis of atropisomers bearing multiple chiral elements has become an emerging field. This review summarizes the rapid progress in this field and indicates challenges, thereby promoting this field to a new horizon.
The catalytic asymmetric synthesis of atropisomers bearing multiple chiral elements has recently become an emerging research field. Chemists have devised metal‐catalyzed or organocatalytic asymmetric reactions for accessing atropisomers with multiple chiral elements, such as those with center chirality, planar chirality, and helical chirality. This review summarizes the rapid developments in this field and indicated the remaining challenges.
Invited for the cover of this issue are the groups of Kazuteru Usui and Satoru Karasawa at Showa Pharmaceutical University and Yasuhiro Kobori of Kobe University. The image depicts chirality control ...of helical compounds through cycles of photocleavage and recombination under sunlight with a “Jack and the Beanstalk” motif. Read the full text of the article at 10.1002/chem.202302413.
“The biggest surprise was the discovery of photoracemization of enantio‐enriched PDHs with relatively high helix inversion.” This and more about the story behind the front cover can be found in the article at 10.1002/chem.202302413).
A series of enantioenriched substituted tetrahydropyrrolo3,2‐cazepine products possessing an axial chirality were synthesized in 63–99% yield through a gold(I)‐catalyzed hydroarylation. DFT ...calculations rationalized the reactivity observed for the formation of such complex molecular frameworks and guided our choice in the pyrrole N‐substituent to isolate configurationally stable compounds.
The Accepted Article version of the above article, published online on 25 May 2021 in Wiley Online Library (wileyonlinelibrary.com), has been withdrawn by agreement between the corresponding author, ...the journal′s Executive Committee, and Wiley‐VCH GmbH, Weinheim. The withdrawal has been agreed upon due to significant conceptual similarities with another of the authors' recently published articles, which was not disclosed during the peer review process.
A Rh‐catalyzed asymmetric synthesis of silicon‐stereogenic dihydrodibenzosilines featuring axially chiral 6‐membered bridged biaryls is demonstrated. In the presence of a RhI catalyst with a chiral ...diphosphine ligand, a wide range of dihydrodibenzosilines containing both silicon‐central and axial chiralities are conveniently constructed in excellent enantioselectivities via dehydrogenative C(sp3)−H silylation. Absolute configuration analysis by single‐crystal X‐ray structures revealed a novel silicon central‐to‐axial chirality relay phenomenon, which we believe will inspire further research in the field of asymmetric catalysis and chiroptical materials.
A Rh‐catalyzed asymmetric synthesis of silicon‐stereogenic dihydrodibenzosilines featuring axially chiral 6‐membered bridged biaryls is demonstrated. A wide range of dihydrodibenzosilines containing both silicon‐central and axial chirality are conveniently constructed in excellent enantioselectivity via intramolecular dehydrogenative C−H silylation.
Chirality is a fundamental property of nature with relevance in biochemistry and physics, particularly in the field of catalysis. Understanding the mechanisms underlying chirality transfer is crucial ...for advancing the knowledge of chiral‐related catalysis. Chiral quantum materials with intriguing chirality‐dependent electronic properties, such as spin‐orbital coupling (SOC) and exotic spin/orbital angular momentum (SAM/OAM), open novel avenues for linking solid‐state topologies with chiral catalysis. In this review, the growth of topological homochiral crystals (THCs) is described, and their applications in heterogeneous catalysis, including hydrogen evolution reaction (HER), oxygen electrocatalysis, and asymmetric catalysis are summarized. A possible link between chirality‐dependent electronic properties and heterogeneous catalysis is discussed. Finally, existing challenges in this field are highlighted, and a brief outlook on the impact of THCs on the overarching chemical–physical research is presented.
Understanding chirality transfer mechanisms is essential for advancing chiral catalysis knowledge. Chiral quantum materials, with unique chiral electronic properties such as spin‐orbital coupling (SOC) and spin/orbital angular momentum (SAM/OAM), provide new connections between solid‐state topologies and chiral catalysis. This review establishes a link between chiral electronic properties and catalysis by discussing the application of topological homochiral crystals (THCs) in heterogeneous catalysis.
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