Suvremeni pristup zaštiti duševnog zdravlja, prema preporukama SZO, potiče razvoj izvanbolničkih psihijatrijskih djelatnosti te nastoji ujediniti sve oblike psihijatrijske zaštite i povezati ...cjelokupnu mrežu psihijatrijskih ustanova. Smjernice upućuju na prevenciju, rano otkrivanje i pojačanu skrb za sve vulnerabilne skupine stanovništva u zajednici, s ciljem da se i liječenje provodi na razini primarne zdravstvene zaštite.Za sada jedini u Hrvatskoj, Centar za mentalno zdravlje Doma zdravlja Zagreb-Zapad upravo je i osnovan s ciljem razvoja modela primjene suvremenih metoda zaštite mentalnog zdravlja u zajednici integriran s postojećim sustavom primarne zdravstvene zaštite.Multidisciplinarni tim zdravstvenih profesionalaca omogućava vertikalni i horizontalni kontinuitet usluge jer pojedini specijalisti rade u sustavu institucionalne skrbi te na taj omogućuju mobilnost u korištenju zdravstvene zaštite. Centar je dobro integriran sa svim djelatnostima doma zdravlja, a sa patronažnom službom razvio je Projekt „ Rodilje sa duševnim smetnjama, probir, rana intervencija i psihološka podrška obitelji“
Provider: - Institution: - Data provided by Europeana Collections- Podzemna skladišta plina predstavljaju značajni segment plinske infrastrukture. Njihova
primarna funkcija je osiguranje pouzdane i ...učinkovite opskrbe prirodnim plinom privatnih i
javnih gospodarskih subjekata. Prirodni plin se skladišti unutar podzemnih geoloških
formacija (ležišta), a ovisno o tipu geološke formacije predodređene su i njegove osnovne
tehničke karakteristike. Kapacitet povlačenja (proizvodnje) i utiskivanja plina bitna je
tehnička karakteristika svakog skladišta plina, a najvećim dijelom je u funkciji ležišnog tlaka,
fizikalnih svojstava geološke formacije i broja bušotina. Za razliku od kapaciteta utiskivanja
plina čija je maksimalna vrijednost održiva tijekom cijelog ciklusa rada skladišta, projektirani
maksimalni kapacitet povlačenja održiv je samo do određene vrijednosti ležišnog tlaka koja se
crpljenjem plina iz ležišta kontinuirano smanjuje. Budući da tijekom zimskih mjeseci
skladište intenzivno radi, poželjno je da vrijednost ležišnog tlaka pri kojoj je moguća
održivost maksimalnog izlaznog kapaciteta bude mala. Navedeno je bitno jer kapacitet
povlačenja skladišta najviše doprinosi sigurnosti opskrbe plinom pri vršnim opterećenjima
plinskog sustava. U okviru ovog doktorskog rada ispitan je utjecaj tehnoloških čimbenika koji
utječu na radne karakteristike skladišta i održivost kapaciteta povlačenja plina. Prvenstveno se
to odnosi na hidrauličke gubitke koji se javljaju prilikom protjecanja plina kroz dijelove
proizvodne opreme, kao i interferenciju rada bušotina uslijed heterogenosti ležišta. Dijelovi
proizvodne opreme koji su razmatrani i ispitani su sapnice i proizvodni niz radnih bušotina.
Navedena problematika, kao i njezin utjecaj na radne karakteristike skladišta plina do danas
nije ispitana na sustavan način. U svrhu ispitivanja postavljenih hipoteza, a na temelju
proizvodnih podataka o radu podzemnog skladišta plina u Republici Hrvatskoj, razvijen je
matematički model skladišta plina. Njegovom upotrebom moguće je ispitati utjecaj pojedinih
segmenata proizvodne opreme na održivost maksimalnog izlaznog kapaciteta skladišta plina.
Unutar modela za proračun pada tlaka kroz bušotinske i redukcijske sapnice postrojenja kao
ključan parametar korišten je koeficijent lokalnog gubitka sapnice koji je u okviru ovog rada
utvrđen eksperimentalno. Uz pomoć razvijenog matematičkog modela ispitane su različite
konfiguracije. Rezultati računalnih simulacija su pokazali da promjer bušotinskih i
redukcijskih sapnica znatno utječe na održivost kapaciteta povlačenja plina. Potvrđen je
utjecaj promjera proizvodnog niza i interferencije rada bušotina na radne karakteristike
skladišta plina.- Storage of natural gas in geological structures such as depleted fields, aquifers and salt
caverns, plays an important role in gas supply system as it balances fluctuation of gas demand
and price. It composes a supply-demand safety and optimizes the gas network capacity
distribution. The importance of underground gas storage is reported worldwide for industrial
and urban gas consumption. Injection and withdrawal capacity represents important technical
characteristics of gas storage facility. It mainly depends on reservoir pressure, physical
properties of geological formation, and the number of working wells.
The present work focuses on determination of influencing parameters that affect performance
of the storage facility and gas withdrawal capacity. Hydraulic loss in fluid flow through gas
storage production equipment, and well interference effects in the surface gathering system,
may have important influence on gas storage performance. The parts of the production
equipment that are investigated are wellhead chokes and well production string (tubing).
Stated issues and their impact on gas storage facility performance are so far not
systematically studied.
Integrated mathematical model is developed based on underground gas storage facility
production data. Using this model, hydraulic loss is determined. A real test case (underground
gas storage in depleted gas reservoirs), which consists of gas storage reservoir linked to
surface facility is analyzed. The mathematical model uses experimentally determined pressure
drop coefficient in chokes. The base case scenario created using real gas storage facility data
(reservoir, fluid, production and pressure data) enables accomplishing a good history match
with given parameters of the gas storage reservoir.
Using the history match simulation case as initial scenario (base case), three different
scenarios are created to determine injection and withdrawal performance of the gas storage
field. First two scenarios include replacement of production equipment (tubing string and
wellhead reduction station chokes). Third scenario analyzes well interference effects
regarding surface gas gathering system. The results indicate that the pressure drop in chokes
in underground gas storage facility has significant impact on gas storage operation and
deliverability. When compared with the base case, all three scenarios indicate an increase in
maximum sustainable gas storage withdrawal capacity. The average discharge coefficient
value of 0.76 is obtained from field measurements.- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Godine 2009., jedna od istraživačkih bušotina u blizini hrvatsko-mađarske granice, umjesto prognoziranog primarnog cilja (miocenski barijerni sprud sastavljen od pješčenjaka i biogenih vapnenaca) 72 ...metra pliće probušila je masivni sediment piroklastičnog toka, debljine 88 metara. Petrološkim analizama jezgre i uzoraka sa sita iz ovog intervala, sediment je determiniran kao devitrificirani vitroklastični stopljeni tuf, tj. ignimbrit. Kao rezultat mikropaleontoloških i palinoloških analiza krovinskih i podinskih sedimenata, starost sedimenta piroklastičnog toka određena je kao najvjerojatnije badenska. Litostratigrafski, ignimbrit pripada formaciji Tar.
Provider: - Institution: - Data provided by Europeana Collections- Žena u trudnoći doživljava niz bioloških i psiholoških poremećaja, koji imaju utjecaj na rast i razvoj djeteta, odnose u obitelji i ...cijelu zajednicu. Pojavnost perinatalnih poremećaja je stanje kojem treba dati veće značenje. Cilj: cilj ovog istraživanja je steći uvid u pojavnost poremećaja raspoloženja koji se javljaju u perinatalnom periodu te povezanost tih poremećaja s postpartalnim periodom i napredovanjem djeteta. Nacrt studije: prospektivna kohortna studija Ispitanici i metode: U istraživanje su bile uključene zdrave trudnice u zadnjem trimestru trudnoće, ukupno 209 trudnica, 197 babinjača i 160 rodilja krajem trećeg mjeseca nakon poroda. Istraživanje je provedeno putem anonimne ankete sa sociodemografskim podacima. Instrumenti koji su korišteni u istraživanju su Edinburška skala postpartalne depresije (EPDS), Beckov inventar depresije (BID) i Beckov inventar anksioznosti (BIA), te kratka psihijatrijska skala (KPSO). Rezultati: Rezultati istraživanja pokazali su da je 15,3% ispitanica imalo blagi rizik za pojavu perinatalne depresije, s rezultatom ≥10 bodova na EPDS, a 7,7% je imalo izražen rizik s rezultatom od 13 do 20 bodova na EPDS. U istraživanju je korišten i BID koji je pokazao da je 3,8% ispitanica imalo blage poremećaje raspoloženja. BIA je pokazao da je 74% ispitanica pokazalo minimalnu razinu anksioznosti, a 1,1% imalo je izraženu anksioznost. Nakon izlaska iz rodilišta 89,2% rodilja dojilo je svoju djecu, a krajem trećeg mjeseca 62,5% učinilo je isto. Depresivnost rodilja krajem trećeg mjeseca nakon poroda koje nisu dojile svoju djecu ststistički je značajna (t=2,05, p<0,05). Spearmanovim koeficijentom korelacije pronađena je niska pozitivna povezanost depresivnosti nakon poroda i promjene tjelesne težine (rs=0,202, p<0,05) i dužine djeteta (rs=0,160, p<0,05) od poroda do trećeg mjeseca. Rodilje koje su kraće dojile treće dijete više su depresivne i anksiozne u usporedbi s ostalim rodiljama koje su dulje dojile svoju djecu. Zaključak: Identifikacija perinatalne depresivnosti tijekom trudnoće omogućava zdravstvenim djelatnicima praćenje rizičnih trudnica sa mjerama pojačanog nadzora, također i provođenje preventivnih intervencija te postavljanje dijagnoze perinatalne depresije uz pomoć kliničkih intervencija.- During the pregnancy women experience a series of biological and psychological disturbances that affect growth and development of the child, family relationships and entire society. There should be payed more attention to perinatal disorders. Aim of study: The aim of this study is to gain insight into the appearance of mood disorders that appear during the perinatal period, and the correlation of these disorders with postpartal period and child's development. Draft of study: prospective cohort study Examinees and methods: The study involved healthy pregnant women in the last trimester of pregnancy, a total of 209 pregnant women, 197 puerperas and 160 pregnant women at the end of the third month after delivery. The study was conducted through an anonymous survey of sociodemographic data. The instruments used in the study were Edinburgh Postnatal Depression Scale (EPDS), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI) and the Brief Psychiatric Rating Scale (BPRS). Results: The results showed that 15.3% of respondents had a slight risk of perinatal depression, with a score of ≥10 points on the EPDS, and 7.7% had a risk with a score from 13 to 20 points on the EPDS. The study also used a BDI, which showed that 3.8% of respondents had mild depressive symptoms. BAI has shown that 74% of repondents showed a minimum level of anxiety, and 1.1% had a pronounced anxiety. After leaving the maternity hospital 89.2% of new mothers breastfed their children, and at the end of third month after delivery 62.5% of them. Statistically significant (t=2.05, p<0.05) was the occurrence of depression among the new mothers who did not breastfeed their children. Spearman's correlation coefficient discovered low positive correlation between depression after delivery and weight changes (rs = 0.202, p <0.05) and the length of the child (rs=0,160, p<0,05) from birth to three months. New mothers who breastfed their third child shorter were more depressed and anxious than other mothers who breastfed their children during longer period. Conclusion: Identification of perinatal depression during pregnancy allows health professionals to follow pregnant women at risk with increased supervision, to provide preventive interventions and diagnosis of perinatal depression with the help of clinical interventions.- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Provider: - Institution: - Data provided by Europeana Collections- Cilj ovoga istraživanja je procjena i prepoznavanje specifičnih osobina ličnosti kod suicidalnih bolesnika sa poremećajem ...raspoloženja (povratni depresivni poremećaj i bipolarno afektivni poremećaj) i kod nesuicidalnih bolesnika sa navedenim poremećajem raspoloženja. Ispitanici i metode: Ovo istraživanje obuhvatilo je ukupno 119 bolesnika sa dijagnozom povratnog depresivnog poremećaja - depresivna epizoda bez psihotičnih simptoma i dijagnozom bipolarno afektivnog poremećaja - depresivna epizoda bez psihotičnih simptoma, prema dijagnostičkim kriterijima MKB-10. Provođeno je od studenog 2012. godine do rujna 2015. godine na Klinici za psihijatriju pri KBC Osijek. Bolesnici su podijeljeni u dvije skupine - eksperimentalnu (suicidalni bolesnici s poremećajem raspoloženja) i kontrolnu (nesuicidalni bolesnici sa poremećajem raspoloženja). Dimenzije ličnosti, težine poremećaja i suicidalnosti su procjenjivane 1. dan (unutar 72h od prijema) i 21. dan liječenja. Procjenski intrumenti primjenjivani u obje skupine su bili: „Temperament and Character Inventory“(TCI) za procjenu dimenzija ličnosti 1. i 21.dan; „Columbia-Suicide Severity Rating Scale“(C-SSRS) u skupini suicidalnih bolesnika 1. i 21. dan; „Reason for Living Inventory“(RFL) u obje skupine 1. dan; „Hamilton Depression Rating Scale“(HAM-D) u obje skupine 1. i 21. dan, te polu-strukturirani sociodemografski upitnik. Rezultati: U skupini bolesnika sa suicidalnim idejama (neovisno o poremećaju raspoloženja), kod prijema, dobili smo značajno više vrijednosti u dimenziji temperamenta i karaktera izbjegavanje štete (HA) (Mann Whitney U Test, P<0,001), a značajno niže vrijednosti za dimenziju upornost (P) (Mann Whitney U Test, P=0,04), samo-vođenja (SD) (Mann Whitney 130 U Test; P<0,001) te kod suradnje (C) (Mann Whitney U Test, P=0,001). Kod otpusta suicidalni bolesnici zadržavaju značajno više vrijednosti u dimenziji HA (Mann Whitney U Test, P<0,001), značajno niže vrijednosti dimenzije SD (Mann Whitney U Test, P<0,001) i dimenzije C (Mann Whitney U Test, P=0,002). Navedeni rezultati potvrđeni su detaljnom analizom suicidalnih bolesnika prema nesuicidalnima u odnosu na karakteristike ličnosti i intenzitet suicidalnog ponašanja. U skupini suicidalnih bolesnika, naspram skupine nesuicidalnih, dobili smo značajno niže vrijednosti na cijelom instrumentu procjene razloga za život (RFL) (Mann Whitney U Test, P<0,001). Na našem uzorku nismo dokazali utjecaj sociodemografskih čimbenika na suicidalno ponašanje.- Suicide and mood disorders represent a major global public health problem. Depressive disorder and bipolar disorder are associated with increased risk for suicide. Beside the existing disorder, underlaying personality traits may be the factor which could influence the appearance of specific mood disorder and suicidal behavior. Aim of the research: The aim of this research was to evaluate and recognize the specific personality traits in patients with mood disorders (recurrent depressive disorder and bipolar disorder) who had suicidal ideation and attempt in comparison to non-suicidal patients with respective mood disorders. Participants and Methods: Our sample consisted of 119 unrelated patients (both male and female) who were suffering form recurrent depressive disorder - depressive episode without psychotic symptoms and bipolar disorder - depressive episode without psychotic symptoms, according to ICD-10 diagnostic criteria. The research was conducted from November 2012 to September 2015 on Deparment of Psychiatry, University Hospital Centre Osijek. The patients were divided in two groups, experimental (patients with mood disorder and suicide ideation/attempt) and control group (non-suicidal patients with mood disorder). Personality traits, severity of depression and suicidal ideation were assessed on the first day (within 72h upon addmittion) and on the 21st day of treatment. The battery of instruments used for assessment was: „Temperament and Character Inventory“(TCI) for personality traits on the 1st and 21st day; „Columbia-Suicide Severity Rating Scale“(C-SSRS) in the group od suicidal patients on the 1st and 21st day; „Reason for Living Inventory“(RFL) in both groups on the 1st day; „Hamilton Depression Rating Scale“(HAM-D) in both groups on 1st and 21st day and semi-structured sociodemographic questionnaire. 132 Results: In the group of suicidal patients (regradless the mood disorder), upon admittion, we found significantly higher scores on the harm-avoidance (HA) temperament dimension (Mann Whitney U Test, P<0,001) and significantly lower scores on persistence (P) (Mann Whitney U Test, P=0,04), self-directedness (SD) (Mann Whitney U Test; P<0,001) and on cooperativeness (C) (Mann Whitney U Test; P=0,001). On the 21st day in the group of suicidal patients there were stil significantly higher scores on HA dimension (Mann Whitney U Test, P<0,001) and significantly lower scores on SD dimension (Mann Whitney U Test, P<0,001) and C dimension (Mann Whitney U Test, P=0,002). These results were confirmed with detailed analysis of the suicidal and non-suicidal group in relation to personality traits and intensity of suicidal behavior. When compared to non-suicidal group, the group of patients with suicidal attempt had significantly lower scores on the complete RFL assessment instrument (Mann Whitney U Test, P<0,001). On our sample we did not confirm the influence of sociodemographic factors on suicidal behavior. Conclusion: High score in harm-avoidance (HA) dimension with low scores in self-directedness (SD), cooperativeness (CO) and persistence (P) were present in the group of suicidal patients with mood disorders upon addmittance and discharge. We assume that the presence of these specific personality traits may determine possible future risk for suicidal behavior in the mentioned group of patients. The results on our sample, confirmed and corroborated relatively new hypothesis for existance stable (not state-dependent) personality traits which could affect individual vulnerability for development of depressive disorder and suicidal behavior.- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Depresija, kao jedna od najrasprostranjenijih psihičkih bolesti današnjice, postaje sve značajniji društveno-medicinski izazov. U odnosu na crkvenu pastoralnu praksu, depresija i druga psihička ...oboljenja također postaju sve zahtjevnijim problemom. Crkva u okviru svoga pastorala bolesnika duhovno skrbi i za oboljele od depresije kao i za druge psihički oboljele osobe. Skrb Crkve primarno je duhovno-vjerske naravi. Crkveno karitativno služenje pomaže također i na društveno-kulturalnom planu, i to ponajviše pastoralno-savjetodavnim djelovanjem u smislu doprinosa što skladnijem uklapanju psihički oboljelih osoba u crkvenu i društvenu zajednicu. U ovome se radu, uz korištenje metode teološko-pastoralnog raspoznavanja, izlažu bitni elementi pastorala osoba oboljelih od depresije, izazovi i mogućnosti pastoralnog pristupa danas, kao i određene perspektive na čijem se ostvarivanju treba više poraditi.
Provider: - Institution: University of Zagreb. School of Dental Medicine. Chair of Neurology. - Data provided by Europeana Collections- Dijabetička polineuropatija (DPN) najčešća je komplikacija ...dijabetesa, a može biti prisutna s i
bez neuropatke boli uz poznatu pojavu depresivnih simptoma u dijabetičara. Kvaliteta života
ključan je parametar na osnovi koje je moguće dati objektivnu procjenu stanja bolesnika, ali i
predvidjeti daljnji tijek bolesti kao i uspjeh liječenja.
Cilj ovog istraživanja je ispitati da li bolna dijabetička polineuropatija i prisutna depresija
značajno utječu na smanjenje kvalitete života bolesnika sa šećernom bolešću.
Ispitanici i metode
Istraživanje je provedeno u KB Merkur- Sveučilišnoj klinici „Vuk Vrhovac“. U istraživanje je
uključeno 240 bolesnika – od kojih 80 bolesnika ima bolnu dijabetičku neuropatiju, 80
bolesnika dijabetičku neuropatiju bez boli, a 80 ispitanika su bolesnici koji su liječeni u KB
Merkur zbog križobolje, ali bez dijabetesa. Kvaliteta života ispitanika ispitivana je SF – 36
(Short Form Health Survey) upitnikom. Za procjenu simptoma i znakova neuropatske boli u
ispitanika korištene su dvije ljestvice VAS (visual analogue scale) i LANSS (Leeds
Assessment of Neuropathic Symptoms and Signs) ljestvica, a za probir depresivnosti
upotrijebljen je BDI -II (Beck Depression Inventory) upitnik.
Rezultati
Vidljivo je da postoji izrazita negativna linearna korelacija jačine boli i kvalitete života u svim
promatranim slučajevima. Korelacija je bila statistički značajna za sve dimenzije SF-36 i za
sva tri načina evaluacije boli, kao i za prisutnost depresivnih simptoma.
Zaključak
U skupini dijabetičara s bolnom DPN statistički je značajno jače prisutna bol kao i depresivni
poremećaji, što omogućuje donošenje zaključka da su upravo bol i depresivni poremećaji
uzrokom konstantno niže kvalitete života u ovih bolesnika.- Neuropahtic pain is defined by IASP as pain that occurs as a direct result of lesions or disease
affecting somatosensory system. Diabetic Peripheral Neuropathy (DPN) is the most common
complication of diabetes and may be found with and without neurophatic pain. It increases
with duration of diabetes. There is also occurrence of depressive symptoms with persons with
diabetes. Quality of life is a key parameter on which to base an objective assessment of the
patient’s condition but also to predict the future course of the disease and the success of
treatment.
Objective The aim of this study was to examine whether Diabetic Peripheral Neuropathy and
present depression significantly impact reduction in quality of life in diabetic patients.
Subjects and Methods The study was conducted in Clinical Hospital Merkur- University
Clinic "Vuk Vrhovac" Reference centre for health care of persons with diabetes of Croatian
Ministry of Health and WHO collaborating institution. The study included 240 patients, 80 of
which had been diagnosed with painful diabetic neuropathy (group B), 80 patients with
diabetic neuropathy without pain (group D). The remaining 80 patients (control group K)
were the patients who were treated in Clinical Hospital Merkur because of back pain and the
diagnosis of DPN was excluded.
In addition to a complete neurological examination included in the General Questionnaire on
the Subject, demographic data was also collected. The EMNG tests of arms and legs were
conducted, Doppler Ultrasound of leg artery, CDFI of carotid arteries and, when necessary,
X-ray, CT or MRI test of lumbosacral spine. The quality of life of the subjects was questioned
using the SF - 36 (Short Form Health Survey). For the assessment of symptoms and signs of
neuropathic pain in patients two VAS (visual analogue scale) scales were used for current
pain and pain during the past month and LANSS (Leeds Assessment of Neuropathic
Symptoms and Signs) scale. Breakthrough of depression was tested by BDI-II (Beck
Depression Inventory) survey.
Results The average age of the subjects was 60.8 years (59.4 +/- 62.2 y). The study included
128 women and 112 men. Most of the subjects diagnosed with diabetes (group B and D)
suffered from type II diabetes (87.4%). The average duration of disease was 18 years.
Subjects with type I diabetes were significantly younger (49.5 years of age) than patients with
type II diabetes (64.2 years of age). In subjects with type I diabetes the average duration of
disease was longer (23.6 years) than in subjects with type II diabetes (17.2 years). Persons
with diabetes without painful DPN suffered more often from type I diabetes compared to the
subjects with painful DPN. As regards to the therapy they were taking, the majority of
subjects (50.6%) were on insulin therapy, around one quarter of the subjects were either on a
combination of peroral and insulin therapy (22.2%) or on a peroral therapy alone (27.2%).
There were statistically significant differences of subjects by type of polyneuropathy
according to the age, i.e. more severe forms were noticed in the older subjects. In 90.4% of
subjects pain occurred couple of years before. In the past month, most of the subjects (47.1%)
had pain every day, followed by those who had pain several times a week (33.8%) or several
times a month. According to the parameter of the current intensity of pain, the highest figures
were found in group B - 5.9 points VAS, and the lowest - 3.1 points VAS in Group D. The
test of degree of pain during the previous month recorded similar results; the highest amount
of 7.1 points VAS found in group B, and the lowest of 3.9 points VAS found in group D. By
gender, women experienced pain significantly stronger than men. This applies both to current
pain (4.8 versus 3.8 points), and pain during the previous month (6.5 versus 4.7 points).
Current pain was significantly and linearly related to age, but not as regards to the pain during
the past month. LANNS scale showed that the subjects of the study had an average of 12.2
points. According to Beck scale (revision II), the subjects got an average of 13.4 points. In
both observed scales women showed on average statistically much higher figures of pain and
depression than men. The stronger the pain that the subjects felt the stronger level of
depression was found. It is interesting to note that the strongest correlation was found between
the degree of pain during the past month according to the VAS scale. It can be concluded that
the degree of pain determined in this manner is the best predictor of the level of depression in
patients.
The largest share of the subjects controlled defecation and urination (84.5%), while only a
very small proportion of subjects controlled it partially or had not at all been able to control it.
In women, the defecation and urination control was significantly weaker than in men. The
same was found for sleep, whereas the women showed worse results. Accordingly, in group
D, it was found that the highest number of subjects (85%) described their sleep as good, quite
the opposite of group B with only 18.75% of subjects describing their sleep as good. The
average number of medication, analgesics, was the highest in Group B (2.1), followed by the
group K (1.7), while the lowest average number of persons taking medication was found in
the subjects from the group D (1,2).
By observing the results in all eight dimensions of the SF-36 scale, it is evident that the
subjects from the general population had higher average results in all dimensions. On the
basis of such comparison it is possible to conclude that the subjects of this study had on
average lower quality of life than would be expected by observing the figures recorded in the
general population. In all dimensions except for GH (general health perceptions), the lowest
average figures were found in group B, and the highest in group D and the subjects from the
Group K showed middle result figures compared to these two groups. It is also interesting to
note that in four dimensions (VT, SF, RE and MH), the subjects of Group D showed higher
average figures when compared to those found in the general population. The correlation of
all 8 dimensions of the SF-36 scale with all three variables used to assess the degree of pain
during the study with the results of the BDI scale was confirmed. It is evident that there is a
strong negative linear correlation between intensity of pain and quality of life in all observed
cases. The correlation was statistically significant for all dimensions of the SF-36, and for all
three methods of pain evaluation, and the presence of depression symptoms.
Conclusion The primary hypothesis - pain and depressive symptoms significantly impact the
quality of life in patients with painful diabetic polyneuropathy was confirmed. The positive
and statistically significant correlation between the two parameters, depression and pain, with
all eight of the observed dimensions of quality of life of SF 36 survey lead to the conclusion
that pain and depression caused a constantly lower quality of life in these patients.- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Cilj ovoga istraživanja bio je ispitati ulogu upalnih faktora u mehanizmu nastanka depresije. Analizirane su koncentracije upalnih čimbenika između skupina zdravih ispitanika i ispitanika oboljelih ...od depresije pri dolasku i mjesec dana od početka liječenja antidepresivima u potonjoj skupini. Temeljem razlika u koncentracijama navedenih čimbenika željelo se potvrditi njihovu ulogu u nastanku depresije i objasniti mehanizam nastanka depresije. Time bi se uz proširivanje spoznaje o uzroku nastanka depresije mogle primijeniti i nove metode liječenja i dijagnostike depresije. Ovim radom pokazano je postojanje statistički značajne razlike u koncentracijama upalnih faktora (CRP, IL -6 i TNF -α) između zdravih ispitanika i onih oboljelih od depresije. Navedene koncentracije su bile više kod depresivnih ispitanika. Nadalje, nakon terapije antidepresivima zabilježena je statistički značajna razlika u koncentraciji CRP u odnosu na početak liječenja, tj. CRP je bio niži nakon terapije antidepresivima. Dobiveni rezultati govore u prilog učinkovitosti terapijskog djelovanja antidepresiva u liječenju depresije kroz snižavanje koncentracije ovoga upalnog čimbenika.
Osnovni cilj studije bio je utvrditi razine triju dimenzija depresivnih simptoma kod studenata medicine u Srbiji, te mijenjaju li se te razine tijekom razdoblja od deset godina. Ova populacijska ...studija obuhvatila je 615 studenata medicine (M=61%; Ž=39%) srednje dobi od 23,60 (SD=1,541) godina, koji su testirani u pet odvojenih ispitivanja od 2002. Do 2012. godine. Depresivni simptomi procjenjivani su pomoću Beckova inventara depresivnosti (BDI ). Srednji zbir BDI za cjelokupni uzorak iznosio je 6,26}6,175. Nije utvrđena značajna razlika u zbiru BDI tijekom deset godina testiranja. Najveći dio ispitanog uzorka (77,24%) nije pokazao depresivne simptome, a također nije utvrđena ni značajna razlika između studenata medicine i ostalih obrazovnih profila prema intenzitetu ovih simptoma. Slično ostalim studijama, žene su bilježile više vrijednosti na svim dimenzijama depresivnosti (osim jedne ispitivane godine), dok je slaba korelacija utvrđena između zbira BDI i dobi (r=0,104; p=0,010). Pošto i dalje postoje neslaganja između studija koje (ne) pokazuju da studenti medicine imaju izražene simptome depresivnosti, potencijalna objašnjenja ovih nalaza trebalo bi tražiti u individualnim karakteristikama pripadnika ove populacije. Prijedlog za buduća istraživanja je da bi u analizu trebalo uključiti i čimbenik stresa, strategije prevladavanja stresa, zadovoljstvo životom, uzroke akademskog neuspjeha i njihov potencijalni utjecaj na razvoj mentalnih poremećaja.
