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32.
  • Molecular basis of inherite... Molecular basis of inherited protein C deficiency results from genetic variations in the signal peptide and propeptide regions
    Cao, Qing; Hao, Zhenyu; Li, Cheng ... Journal of thrombosis and haemostasis, 11/2023, Letnik: 21, Številka: 11
    Journal Article
    Recenzirano

    Inherited protein C deficiency (PCD) caused by mutations in protein C (PC) gene (PROC) increases the risk of thrombosis. Missense mutations in PC’s signal peptide and propeptide have been reported in ...
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  • Analytical considerations a... Analytical considerations and plans to standardize or harmonize assays for the reference bone turnover markers PINP and β-CTX in blood
    Bhattoa, Harjit P.; Cavalier, Etienne; Eastell, Richard ... Clinica chimica acta, 04/2021, Letnik: 515
    Journal Article, Web Resource
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    •IOF and International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) consider that Procollagen type I N-propeptide (PINP) and C-terminal telopeptide of type I collagen (β-CTX) are ...
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34.
  • IGF-II regulates lysyl oxid... IGF-II regulates lysyl oxidase propeptide and mediates its effects in part via basic helix-loop-helix E40
    Adewale, Adegboyega Timothy; Sharma, Shailza; Mouawad, Joe E. ... Matrix biology, 09/2024, Letnik: 132
    Journal Article
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    •The mediators of extracellular matrix deregulation downstream of Insulin-like growth factor II (IGF-II) were investigated.•Levels of pro-Lysyl Oxidase (ProLOX), its cleavage products LOX, and Lysyl ...
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35.
  • Revisiting Circulating Extr... Revisiting Circulating Extracellular Matrix Fragments as Disease Markers in Myelofibrosis and Related Neoplasms
    Hasselbalch, Hans Carl; Junker, Peter; Skov, Vibe ... Cancers, 08/2023, Letnik: 15, Številka: 17
    Journal Article
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    Philadelphia chromosome-negative chronic myeloproliferative neoplasms (MPNs) arise due to acquired somatic driver mutations in stem cells and develop over 10–30 years from the earliest cancer stages ...
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  • The role of propeptide-medi... The role of propeptide-mediated autoinhibition and intermolecular chaperone in the maturation of cognate catalytic domain in leucine aminopeptidase
    Baltulionis, G.; Blight, M.; Robin, A. ... Journal of structural biology, 09/2021, Letnik: 213, Številka: 3
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    Display omitted •AO-proLapA and AO-mLapA are novel fungal M28 aminopeptidase structures.•AO-LapA propeptide acts as intramolecular chaperone.•Structures reveal molecular mechanism of AO-LapA ...
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  • Effects of Yearly Zoledroni... Effects of Yearly Zoledronic Acid 5 mg on Bone Turnover Markers and Relation of PINP With Fracture Reduction in Postmenopausal Women With Osteoporosis
    Delmas, Pierre D; Munoz, Francoise; Black, Dennis M ... Journal of bone and mineral research, September 2009, Letnik: 24, Številka: 9
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    In patients with osteoporosis treated with antiresorptive agents, reduction in bone turnover explains much of the observed fracture risk reduction. Lower levels of bone turnover markers (BTMs) appear ...
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38.
  • Transgenic red carp (Cyprin... Transgenic red carp (Cyprinus carpio) with LcMSTN1 propeptide: Enhanced growth and unchanged muscle fat content
    Zhang, Yu; Tang, Zeyuan; Liu, Zhifei ... Aquaculture, 08/2021, Letnik: 541
    Journal Article
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    Growth and meat quality are concerned issues in aquaculture. The inhibition of MSTN can lead to significant muscle proliferation in mammals, as well as a decrease in muscle fat content. In fish, the ...
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  • Liraglutide does not change... Liraglutide does not change bone turnover in clozapine- and olanzapine-treated schizophrenia overweight patients with prediabetes – randomized controlled trial
    Maagensen, Henrik; Larsen, Julie R.; Jørgensen, Niklas R. ... Psychiatry research, February 2021, 2021-Feb, 2021-02-00, 20210201, Letnik: 296
    Journal Article
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    •No effect of liraglutide was seen on bone turnover markers in patients with prediabetes and schizophrenia treated with olanzapine and/or clozapine.•Liraglutide induced weight loss, but weight loss ...
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  • Bone markers in polycystic ... Bone markers in polycystic ovary syndrome: A multicentre study
    Lingaiah, Shilpa; Morin‐Papunen, Laure; Piltonen, Terhi ... Clinical endocrinology (Oxford), December 2017, Letnik: 87, Številka: 6
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    Summary Objective Hyperandrogenism, hyperinsulinaemia and obesity, known characteristics of polycystic ovary syndrome (PCOS), may influence bone mineral density and biochemical markers of bone ...
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