ZusammenfassungEinleitungBei Mitarbeiter*innen mit gefährdeter beruflicher Teilhabe ist eine ganzheitliche und arbeitsplatzorientierte Diagnostik erforderlich, um Gesundheitsprobleme zu verstehen und ...individuelle Lösungsansätze zu finden. Wir entwickelten eine neuartige diagnostische Leistung zur Sicherung beruflicher Teilhabe, die rehabilitative und betriebsärztliche Expertise verbindet. Ziel der Machbarkeitsstudie war die Bewertung der Implementierung sowie die Analyse von Veränderungen von Gesundheit und Arbeitsfähigkeit.MethodenDie Beobachtungsstudie (Deutsches Register Klinischer Studien: DRKS00024522) schloss Mitarbeiter*innen mit gesundheitlichen Einschränkungen und eingeschränkter Arbeitsfähigkeit ein. Die Teilnehmenden erhielten ein betriebsärztliches Erstgespräch, eine zweitägige ganzheitliche Diagnostik in einer Rehabilitationseinrichtung und bis zu vier betriebliche Nachsorgegespräche. Fragebogendaten, die im Erstgespräch und im letzten Nachsorgegespräch erhoben wurden, umfassten subjektive Arbeitsfähigkeit (0–10 Punkte) und allgemeine Gesundheit (0–10).ErgebnisseFür die Analyse wurden Daten von 27 Teilnehmenden berücksichtigt. Die Teilnehmenden waren zu 63 % weiblich und im Durchschnitt 46 Jahre alt (SD = 11,5). Vom betriebsärztlichen Erstgespräch zum letzten Nachsorgegespräch berichteten die Teilnehmenden eine Verbesserung ihrer allgemeinen Gesundheit (Differenz = 1,52; 95 % KI 0,37–2,67; d = 0,97).Diskussion und FazitDas Modellvorhaben GIBI bietet einen niedrigschwelligen Zugang zu einem vertrauensvollen, ganzheitlichen und arbeitsplatzorientierten Angebot, das die berufliche Teilhabe stärken kann. Eine erfolgreiche Durchführung von GIBI erfordert eine enge und intensive Zusammenarbeit zwischen Betriebsärzt*innen und Rehabilitationseinrichtungen. Zur Bewertung der Wirksamkeit wird aktuell eine randomisierte kontrollierte Studie (n = 210) mit Wartekontrollgruppe durchgeführt.
This analysis extrapolates information from previous studies and experiences to bring physical medicine and rehabilitation perspective and intervention to the multidisciplinary treatment of COVID-19. ...The purpose of pulmonary rehabilitation in COVID-19 patients is to improve symptoms of dyspnea, relieve anxiety, reduce complications, minimize disability, preserve function, and improve quality of life. Pulmonary rehabilitation during the acute management of COVID-19 should be considered when possible and safe and may include nutrition, airway, posture, clearance technique, oxygen supplementation, breathing exercises, stretching, manual therapy, and physical activity. Given the possibility of long-term disability, outpatient posthospitalization pulmonary rehabilitation may be considered in all patients hospitalized with COVID-19.
ABSTRACT Purpose: to analyze the test results of speech perception and spoken language in children with hearing loss and auditory neuropathy spectrum disorder, users of hearing aids or cochlear ...implants. Methods: a systematic review of the literature based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Consultation was performed in databases, considering studies from 1996 to 2021, selecting the studies that presented the results of speech perception or spoken language in children with bilateral auditory neuropathy spectrum disorder, with no structural alterations of the ear and/or vestibulocochlear nerve, or other associated impairments. Descriptive analysis was performed. Literature Review: among 1,422 studies found, 15 were included. Variability in the sample size, types of studies, evaluation procedures and methodological questions were observed. The cochlear implants and hearing aids contributed to the development of speech perception and spoken language in children with auditory neuropathy spectrum disorder, since skills such as auditory comprehension and speech intelligibility, were achieved. Conclusion: 15 studies suggest that cochlear implants and hearing aids may be effective for speech perception and spoken language development in children with auditory neuropathy spectrum disorder, with no other associated impairments. The need for further research with a high methodological rigor is highlighted.
RESUMO Objetivo: analisar os resultados de testes percepção da fala e linguagem falada de crianças com espectro da neuropatia auditiva, usuárias de aparelho de amplificação sonora individual ou implante coclear. Métodos: revisão sistemática da literatura, baseada no guideline Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Levantaram-se, em bases de dados, estudos entre 1996 e 2021, que apresentavam os resultados de percepção da fala ou linguagem falada de crianças com espectro da neuropatia auditiva bilateral, sem alterações estruturais da orelha/nervo vestíbulo-coclear, ou comprometimentos associados. Os dados foram analisados descritivamente. Revisão da Literatura: dentre 1422 estudos encontrados, 15 foram incluídos. Observou-se variabilidade no tamanho das amostras, tipos de estudos, procedimentos de avaliação e questões metodológicas. O implante coclear e o aparelho de amplificação sonora individual contribuíram para o desenvolvimento da percepção da fala e linguagem falada de crianças com espectro da neuropatia auditiva, pois foram alcançadas habilidades, como a compreensão auditiva e inteligibilidade da fala. Conclusão: 15 estudos sugeriram que o implante coclear e o aparelho de amplificação sonora individual podem ser efetivos para o desenvolvimento da percepção da fala e linguagem falada de crianças com espectro da neuropatia auditiva sem outros comprometimentos associados. Ressalta-se a necessidade de pesquisas com alto rigor metodológico.
Purpose: to investigate genetic recurrence and molecular markers for dyslexia in two candidate genes in the Brazilian population. Methods: a cross-sectional, case-control, observational study, with ...five single nucleotide polymorphisms (SNPs) studied in DYX1C1 and KIAA0319 genes in 86 subjects with dyslexia and 66 controls, matched for gender and age. SNPs were genotyped using the polymerase chain reaction technique in real time, and distribution of genotypic and allelic frequencies between the groups was analyzed. Results: it was determined that 68% of the subjects with dyslexia present a family history of learning difficulties. The DYX1C1 gene did not demonstrate an association with dyslexia, which was found regarding the rs9461045 marker of the KIAA0319 gene. Conclusion: a family history of learning problems was present in more than two-thirds of the group with dyslexia, indicating that this is an important risk factor. An association with dyslexia in the rs9461045 marker was noted, making the study the first one to show an association of the KIAA0319 gene with dyslexia, in Latin America. Keywords: Dyslexia; Heredity; Endophenotypes; Genetics
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