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  • Anemija in srčno popuščanje = Anemia and heart failure
    Šebeštjen, Miran
    While advances in treatment strategies and pharmacotherapy have produced a dramatic reduction in the mortality of patients with heart failure during the past 15 years, it is still a major challenge ... to improve patient well-being, reduce hospitalisations and further reduce mortality. The prevalence of heart failure is not decreasing and heart failure is currently the reason for hospitalisation in over 25% of admissions to internal medicine and cardiology departments. It has recently become apparent that anemia is present in 20 to 30% of patients with heart failure and the severity of anemia has important implications regarding outcome and prognosis. Anemia may be due to a numberof causes, including iron and vitamin deficiency, insidious blood loss, hemodilution, renal impairment and bone marrow depression with resistance to erythropoietin. Preliminary data show that appropriate treatment of anemia based on correction of the underlying cause with, in most patients, the addition of exogenous erythropoietin and iron therapy improves ventricular function and the clinical status. Treatment of anemia has opened a new frontier in the management of heart failure. We await the results of ongoing clinical trials for more detailed information regarding appropriate hemoglobintargets, choice of medication and dosing and the degree of improvement that may be expected when the issue of anemia is properly addressed.
    Vir: Slovenska kardiologija : znanstveno strokovna revija za področje srčno-žilne medicine. - ISSN 1581-8543 (Letn. 3, št. 1, 2006, str. 52-57)
    Vrsta gradiva - članek, sestavni del
    Leto - 2006
    Jezik - slovenski
    COBISS.SI-ID - 21312473

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