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  • Nanocellulose-based antimicrobial microparticles as an alternative to toxic nano-biocides [Elektronski vir]
    Kokol, Vanja ...
    Dialdehyde cellulose nanofibrils (CNF) and nanocrystals (CNC) were prepared via periodate oxidation (CNF/CNC-ox) and subsequently functionalized with hexamethylenediamino (HMDA) via the Schiff-base ... reaction. This resulted to an porous and micro-sized (0.5-10 µm) particles (CNF/CNC-oxHMDA) that can catch bacteria by multi-targeted (ionic and hydrophobic) non-specific modes of action, and prevent them from growing at minimum nontoxic (both in vitro to human lung cells and in vivo to Daphnia magna) concentrations (< 0.2 wt%). The hydrodynamically smaller (0.5-1 µm) CNC-oxHMDA decorated with aldehyde, anionic, amino and hydrophobic surface groups was found to be the most effective, with up to log 9 of bacteria reduction at >0.4 wt.% and a bactericidal effect. While the antimicrobial less-active CNF/CNC-ox were fully biodegradable in composting soil within 24 weeks, this process was inhibited considerably for CNF/CNC-ox-HMDA, indicating their different stability and disposal after use (e.g. composting vs. recycling). As such, however, they can serve as an alternative to nano-biocides (such as metal nanoparticles), which are limited by their toxicity for humans and the environment.
    Vir: ISWFPC 2023 [Elektronski vir] : International Symposium on Wood, Fiber and Pulping Chemistry : Venice, Italy, 4th-7th July 2023 : conference proceedings. Vol. 1, Oral presentations (Str. 259-261)
    Vrsta gradiva - prispevek na konferenci ; neleposlovje za odrasle
    Leto - 2023
    Jezik - angleški
    COBISS.SI-ID - 161965315

    Povezava(-e):

    https://www.iswfpc2023.org/wp-content/uploads/2023/07/02_ISWFPC2023_ORAL_ABSTRACT.pdf

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