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  • Determination of C-reactive protein by turbidimetric immunoassay (TIA) in sheep
    Vojtic, Igor ; Krajnc, Stanislav
    C-reactive protein (CRP) has been shown to be an important part of acute phase reaction in domestic mammals. We investigated the presence of CRP in Slovenian sheep in order to obtain a better ... understanding of the distribution of CRP in ovine species. The reference sample comprised fifty-two clinically healthy female sheep (14 Solča breed and 38 Bovško breed, aged between six months and four years). Assay for CRP was carried out in blood serum using a turbidimetric immunoassay (TIA) with rabbit polyclonal antibodies against human CRP molecule. Values for CRP ranged between 0.000 and 13.600 mg/l, whileconcentration of CRP was 6.280_+0.429 mg/l.Sample reference limits (95 % confidence interval) were between 0.086 and 12.474 mg/l. Mean CRP concentrations for both breeds were 5.235_+0.429 for Bovško sheep and 9.115_+0.647 mg/l for Soča sheep, respectively (P<0.001). It can be concluded that CRP serum levels represent the result of compromised metabolic and immunological activity. This study was thought to be helpful in distinguishingbetween normal and pathological serum values for CRP in sheep.
    Vir: Veterinarski arhiv : časopis Veterinarskog fakulteta Sveučilišta u Zagrebu = journal of the Veterinary Faculty, University of Zagreb. - ISSN 0372-5480 (70, št. 3, 2000, str. 151-157)
    Vrsta gradiva - članek, sestavni del
    Leto - 2000
    Jezik - angleški
    COBISS.SI-ID - 1725228

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