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Kim, Dong-Hyun; Lee, Hyo-Jung; Oh, Young-Jun; Kim, Min-Jung; Kim, Sung-Hoon; Jeong, Tae-Sook; Baek, Nam-In
Archives of pharmacal research, 10/2005, Letnik: 28, Številka: 10Journal Article
An iridoid glycoside, oldenlandoside III (5) was isolated from the n-butanol fraction of methanol extracts of the aerial parts of Oldenlandia diffusa Roxb. along with six others previously characterized iridoid glycosides; geniposidic acid (1), scandoside (2), feretoside (3), 10-omicron-benzoylscandoside methyl ester (4), asperulosidic acid (6) and deacetylasperulosidic acid (7). Compounds 1, 2, and 7 inhibited LDL-oxidation, and showed 63.3+/-2.0, 62.2+/-1.6, and 63.8+/-1.5% inhibition, respectively, at a concentration of 20 microg/mL.
