In this paper, a multiple stubs loaded ring resonator (MSLRR) is proposed to design directly coupled multi-band bandpass filters (BPFs) with mixed electric and magnetic coupling (MEMC). The proposed MSLRR exhibits multiple-mode resonant behavior. The increased number of loaded stubs excite many more useful resonant modes, but these resonant modes can be still independently controlled. As examples, a dual-band BPF, a tri-band BPF, a quad-band BPF, and a quint-band BPF using different types of MSLRRs are designed and fabricated. The passband frequencies and return losses (RLs) of these multi-band BPFs can be independently controlled. A dual-mode open loop resonator is then introduced in the quint-band BPF to enhance the sixth resonant mode of the MSLRR to produce the sixth passband so that a sext-band BPF is also presented. Multiple transmission zeros due to the cancelling effect of MEMC and virtual grounds in the MSLRR can be observed around the passbands resulting in sharp passband selectivity and high band-to-band isolation. Moreover, all of the fabricated multi-band BPFs have compact sizes, good RLs, and low insertion losses. Good agreements are observed between the simulated and measured results.