The efficiency performance of multi-motor-driven system highly depends on the power management. Three aspects of contribution have been made in this study. 1) A predictive power management for a DMPS is developed. To improve the performance of the predictive power management, an adaptive velocity predictor is proposed and the coefficients of proposed predictor can update its parameters according to identified driving patterns. Simulation results show that the new velocity predictor have best prediction performance compared with traditional predictors. 2) A neural network based power management is proposed. According to the optimization results of dynamic programming, radial-basis-function neural network is trained. The input dimensions and the number of hidden layer neurons of the neural network are optimized. 3) The performance of proposed control strategies are compared with three different drive cycles including MANHATTAN cycle, Japanese 1015 cycle, and UDDSHDV cycle. Simulation results indicate that compared with original control strategy, the predictive control strategy and neural network based control strategy show better efficiency performance. The neural network based strategy is verified by hardware-in-loop experiment and experiment results indicate that the control performance in real hardware shows similar property with simulation results.