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  • Abnormal intracellular calc...
    Dubovsky, S L; Murphy, J; Thomas, M; Rademacher, J

    The American journal of psychiatry 149, Številka: 1
    Journal Article

    The authors measured intracellular Ca2+ concentrations in four manic and five bipolar depressed patients and seven comparison subjects. Platelet and lymphocyte intracellular Ca2+ concentrations were comparable. The patients' mean intracellular Ca2+ concentrations were higher than those of the comparison subjects and demonstrated more interindividual variation. These findings suggest a diffuse abnormality in mechanisms affecting intracellular calcium homeostasis in bipolar disorder.