E-viri
Recenzirano
-
Aldred, Matthew P.; Li, Fuxuan; Kuang, Rong; Thomas, Owen L.; Davies, Thomas E.; Taylor, Stuart H.; Miedziak, Peter J.; Graham, Andrew E.
Tetrahedron letters, 04/2024, Letnik: 140Journal Article
Display omitted Nanoporous silicate materials, made by an operationally simple evaporation-induced self-assembly (EISA) approach, efficiently catalyze the formation of 2-substituted 2,3-dihydroquinazolin-4(1H)-ones from aldehydes and dimethyl acetals. This methodology can be extended to encompass the reaction of ketones and ketals to provide facile access to 2,2-disubstituted and spiro dihydroquinazolin-4(1H)-ones in high yields and short reaction times.
