Currently one major barrier for the design of cast high-strength and high-toughness Al alloys is hot tearing. In this work, a strategy of combination of squeeze casting and microalloying (Ca/Ni eutectic elements) in Al-Cu-Mn based alloys was employed to inherit the excellent mechanical properties of Al-Cu alloys whilst simultaneously reducing their tendency to hot tearing. The developed alloys exhibit comparable castability (fluidity and hot tear resistance) to A356, which is widely available commercially. However, their comprehensive mechanical properties far exceed those of A356. Trace Ca/Ni additions markedly reduce the grain size of the alloy and simultaneously increase the fraction of intergranular low melting point eutectic liquid phases, which is beneficial to the improvement of liquid feeding. The fine equiaxed grains have excellent thermal shrinkage coordination, while the high volume fraction eutectic liquid phase delays the development of grain cohesive skeleton. Accordingly, the localized shrinkage stress/strain at the hot spot is released timely, thus inhibiting the emergence and propagation of hot cracks in the brittle solidification interval. The diminished hot tearing susceptibility is attributed to the reduced load onset temperature and load values in the hot spot region. A new intergranular bridging mechanism is discovered in low-Ca alloys: based on compositional segregation-induced nucleation of an intergranular bridging skeleton, which strengthens the intergranular adhesive force and effectively reduces the hot tearing tendency of the alloys. The alloys with high-Ca/Ni additions, however, reduce the hot tearing tendency by healing cracks through eutectic liquid phase backfill. The results of the hot tearing experiments of the developed alloys are analyzed with the current hot tearing evaluation criteria. The results demonstrate that the predictions of the Kou's criterion provide guidelines for the design of alloys that are resistant to hot tearing. •Trace amounts of Ca and Ni elements dramatically reduce the hot tearing tendency of the matrix alloy.•The Ca/Ni rich eutectic phase retards the formation of brittle dendritic skeleton and inhibits the initiation and extension of hot cracks.•Eutectic colonies induce the development of bridges between grains and enhance the cohesion of grain boundaries.