The author presents the history of the Church of Egypt after the Council of Chalcedon (451), and trying to determine the final destruction of the unity of Patriarchate of Alexandria. At the beginning of the crisis were the decisions taken at the Council, but the process of creating a separate patriarchates (Melkite and Monophysite) in Egypt last long. Some researchers, such as William H.C. Frend, consider turning point in this process the death of the Emperor Justinian (565), while in the East began to create a separate Monophysite Church hierarchy. Such conclusions appear premature regards Egypt, although these may be correct with regard to Syria. It seems that the creation of two separate Christian Churches in Egypt take place in Egypt later, during the reign of Emperor Heraclius (610-641).