This article focuses on ethical quandaries in the practice of indirect personality assessment in non-health-service psychology. Indirect personality assessment methods do not involve face-to-face interaction. Personality assessment at a distance is a methodological development of personality and social psychology, psychobiography, and psychohistory. Indirect personality methods are used in clinical, forensic, law enforcement, public safety, and national security settings. Psychology practice in non-health-service settings creates tensions between principles of beneficence and duty to society. This article defines methods of indirect personality assessment and some ethical ramifications. Their application in non-health-service settings occurs in the context of intense controversy over the ethics of psychologists' participation in work settings where there are third-party loyalties, absence of voluntary informed consent, presence of nonstipulated harms, and absence of legal and ethical accountability. A hypothetical case example illustrates typical quandaries encountered in a national security assessment. This article provides a framework for critically examining ethical quandaries, a contemporary conceptual and process model for integrative moral cognition, and parameters for ethical reasoning by the individual practitioner under the exigencies of real-world practice.