Cilj: Ispitati i utvrditi prisutnost poteškoća i kvalitetu života bolesnika s kroničnom leukemijom s obzirom na spol, bračni status i starosnu dob bolesnika.Metode: Za potrebe istraživanja proveden je anketni upitnik među 44 bolesnika koji imaju dijagnosticiranu kroničnu leukemiju duže od godine dana. Istraživanje je provedeno u razdoblju od 15.6.2021. do 14.8.2021. godine. Ispitanici su anketirani preko anketnog upitnika koji je proveden pismeno, zaokruživanjem jednog od ponuđenih odgovora.Rezultati: U provedenom istraživanju sudjelovalo je 44 ispitanika, od kojih su 58,82% muškarci i 41,18% žene. Za većinu ispitanika postoji statistički značajna povezanost u prisutnosti poteškoća i kvaliteti života s obzirom na starosnu dob.Zaključci: Poteškoće uzrokovane leukemijom koje utječu na kvalitetu života s obzirom na spol bolesnika izraženije su kod žena. Poteškoće uzrokovane leukemijom koje utječu na kvalitetu života s obzirom na bračni status ispitanika nisu značajno izražene kod nijedne grupe ispitanika. Postoji povezanost između učestalosti općih poteškoća i starosne dobi, odnosno osobe starije životne dobi bilježe učestalije opće poteškoće. Objective: To examine and determine the presence of difficulties and quality of life of patients with chronic leukaemia regarding gender, marital status, and age of the patient.Methods: For the purposes of the research, a survey questionnaire was conducted among 44 patients who were diagnosed with chronic leukaemia for more than a year. The research was conducted in the period from 15 June 2021 to 14 August 2021. Respondents were interviewed using a written questionnaire, circling one of the answers provided.Results: 44 respondents participated in the study, of which 58.82% were men and 41.18% women. For most respondents, there is a statistically significant association in the presence of difficulties and quality of life with respect to age.Conclusion: Difficulties caused by leukaemia that affect the quality of life, depending on the gender of the patient, are more pronounced in women. Difficulties caused by leukaemia that affect the quality of life regarding the marital status of the respondents are not significantly expressed in any group of respondents. There is a association between the frequency of general difficulties and age, that is, older people report general difficulties more frequently.