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McDonald, Brooke K.; Laohamonthonkul, Pawat; Yu, Chien-Hsiung
Trends in cell biology, June 2023, 2023-06-00, 20230601, Letnik: 33, Številka: 6Journal Article
Emergent evidence has shown that abnormal buildup of stray self-nucleic acids is a pathological feature observed across many neurodegenerative conditions. Here, we discuss how these self-nucleic acids act as a driver of disease by triggering harmful inflammatory responses. Understanding these pathways and targeting them has the potential to prevent neuronal death at the early stages of disease.
