During the last decades, North America as well as Europe have experienced a significant boom of craft breweries. While it has been understood mainly as a result of neolocalism, we argue that this view is overly unilateral and depending on spatial context. Other factors like glocalization may potentially also affect the emergence of craft breweries. This paper examined the factors influencing the expansion of craft breweries in seven regions of Czechia and Poland, two Central European countries that share similar history but differ in their brewing traditions. Based on semi-structured interviews with representatives of 59 breweries, we identified important similarities but also fundamental differences. Many breweries have indeed been significantly influenced by neolocalism, while some did not capitalize on it, and others even directly rejected it. The role of spatial context has also manifested, particularly through the increased importance of glocalization in several regions.