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  • Epinephrine promotes COX-2-...
    Muthuswamy, Ravikumar; Okada, Nana J; Jenkins, Frank J; McGuire, Kandace; McAuliffe, Priscilla F; Zeh, Herbert J; Bartlett, David L; Wallace, Callen; Watkins, Simon; Henning, Jill D; Bovbjerg, Dana H; Kalinski, Pawel

    Brain, behavior, and immunity, 05/2017, Letnik: 62
    Journal Article

    Highlights • Inflammation promotes catecholamine-driven immune suppression. • COX-2 blockade prevents the induction of suppressive factors by epinephrine. • COX-2 blockade counteracts suppressive activity of epinephrine-treated macrophages. • Our data suggest that COX-2 blockade may reduce the immunosuppressive effects of psychologic stress.