E-viri
Recenzirano
-
Higuchi, T.T; Granberg, C.F; Fox, J.A; Husmann, D.A
The Journal of urology, 12/2010, Letnik: 184, Številka: 6Journal Article
Purpose We determined if ileal/colonic bladder augmentation performed in patients with congenital bladder abnormalities is an independent risk factor for bladder malignancy. Materials and Methods We reviewed a registry of patients with bladder dysfunction due to neurological abnormalities, exstrophy and posterior urethral valves. Individuals treated with augmentation cystoplasty were matched (1:1) to a control group treated with intermittent catheterization based on etiology of bladder dysfunction, gender and age (± 2 years). Results We evaluated 153 patients with an ileal/colonic cystoplasty and a matched control population. There was no difference (p = 0.54) in the incidence of bladder cancer in patients with augmentation cystoplasty (7 patients 4.6%) vs controls (4 2.6%). In addition, there was no difference between the 2 groups regarding age at diagnosis (51 vs 49.5 years, p >0.7), stage (3.4 vs 3.8, p >0.5), mortality rate (5 of 7 71% vs 4 of 4 100%, p >0.4) or median survival (18 vs 17 months, p >0.8). Irrespective of augmentation status patients with a history of renal transplant on chronic immunosuppression had a significantly higher incidence of bladder cancer (3 of 20 15%), compared to patients who were not immunosuppressed (8 of 286 2.8%, p = 0.03). Conclusions In patients with congenital bladder dysfunction ileal/colonic bladder augmentation does not appear to increase the risk of bladder malignancy over the inherent cancer risk associated with the underlying congenital abnormality. In addition, immunosuppression irrespective of bladder treatment is an independent risk factor for malignancy in this patient population.
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|
Vir: Osebne bibliografije
in: SICRIS
To gradivo vam je dostopno v celotnem besedilu. Če kljub temu želite naročiti gradivo, kliknite gumb Nadaljuj.