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  • Ventricular Repolarization ...
    Iacoviello, Massimo, MD, PhD; Forleo, Cinzia, MD, PhD; Guida, Pietro, PhD; Romito, Roberta, MD; Sorgente, Antonio, MD; Sorrentino, Sandro, PhD; Catucci, Silvana, MD; Mastropasqua, Filippo, MD; Pitzalis, Mariavittoria, MD, PhD

    Journal of the American College of Cardiology, 07/2007, Letnik: 50, Številka: 3
    Journal Article

    Ventricular Repolarization Dynamicity Provides Independent Prognostic Information Toward Major Arrhythmic Events in Patients With Idiopathic Dilated Cardiomyopathy Massimo Iacoviello, Cinzia Forleo, Pietro Guida, Roberta Romito, Antonio Sorgente, Sandro Sorrentino, Silvana Catucci, Filippo Mastropasqua, Mariavittoria Pitzalis We evaluated whether the analysis of ventricular repolarization dynamicity by calculating the slope of linear regression analysis of QT and RR intervals was associated with an increased arrhythmic risk in a group of patients with idiopathic dilated cardiomyopathy (DCM). Both univariate and multivariate analysis showed that QT dynamicity, nonsustained ventricular tachycardia, and left ventricular ejection fraction were independently associated with arrhythmic events. These results suggest a possible clinical usefulness of QT dynamicity analysis in stratifying arrhythmic risk in DCM patients.