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Patel, D J; Ma, J-B; Yuan, Y-R; Ye, K; Pei, Y; Kuryavyi, V; Malinina, L; Meister, G; Tuschl, T
Cold Spring Harbor Symposia on Quantitative Biology, 2006, Letnik: 71Journal Article
We outline structure-function contributions from our laboratories on protein-RNA recognition events that monitor siRNA length, 5 -phosphate and 2-nucleotide 3 overhangs, as well as the architecture of Argonaute, its externally bound siRNA complex, and Argonaute-based models involving guide-strand-mediated mRNA binding, cleavage, and release.
