E-viri
Recenzirano
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Christophers, E.
British journal of dermatology (1951), March 2008, Letnik: 158, Številka: 3Journal Article
Summary Psoriasis is a heterogeneous disorder with many different phenotypes. Further, different forms may alter their morphology and course of disease in that, for instance, plaque‐type psoriasis may become pustular and vice versa. With advancing insight in immunopathology phenotype switching can now be explained by directional changes from T cell‐mediated pathology to an inflammatory neutrophilic pattern which is driven by innate signalling. Within this framework not a single ‘antigen’ but various causative agents play a key role.
