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  • Natural History of Hepatitis C
    Lingala, Shilpa; Ghany, Marc G

    Gastroenterology clinics of North America, 12/2015, Letnik: 44, Številka: 4
    Journal Article

    Hepatitis C infection is a common cause of cirrhosis and indication for liver transplantation in the United States. The incidence of chronic hepatitis C has been declining, but rates of cirrhosis and hepatocellular carcinoma are projected to increase. The outcome of chronic hepatitis C is variable. It is estimated that 20% to 25% will develop cirrhosis over a 25-year to 30-year period. The rate of disease progression is influenced by many host, viral, and environmental factors. Few can be modified.