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Gesundheit, Benjamin; Grisaru-Soen, Galia; Greenberg, David; Levtzion-Korach, Osnat; Malkin, David; Petric, Martin; Koren, Gideon; Tendler, Moshe D; Ben-Zeev, Bruria; Vardi, Amir; Dagan, Ron; Engelhard, Dan
Pediatrics (Evanston), 08/2004, Letnik: 114, Številka: 2Journal Article
Genital neonatal herpes simplex virus type 1 (HSV-1) infection was observed in a series of neonates after traditional Jewish ritual circumcision. The objective of this study was to describe neonate genital HSV-1 infection after ritual circumcision and investigate the association between genital HSV-1 after circumcision and the practice of the traditional circumcision. Eight neonates with genital HSV-1 infection after ritual circumcision were identified. The average interval from circumcision to clinical manifestations was 7.25 +/- 2.5 days. In all cases, the traditional circumciser (the mohel) had performed the ancient custom of orally suctioning the blood after cutting the foreskin (oral metzitzah), which is currently practiced by only a minority of mohels. Six infants received intravenous acyclovir therapy. Four infants had recurrent episodes of genital HSV infection, and 1 developed HSV encephalitis with neurologic sequelae. All four mohels tested for HSV antibodies were seropositive. Ritual Jewish circumcision that includes metzitzah with direct oral-genital contact carries a serious risk for transmission of HSV from mohels to neonates, which can be complicated by protracted or severe infection. Oral metzitzah after ritual circumcision may be hazardous to the neonate.
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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