Emerging data driven digital economy and Industry 4.0 transforms all sectors including industry, research and business. It requires new types of the general workforce and specialists that can effectively use digital and data technologies, variety of tools and global infrastructure services, and are capable for personal skills management and self-study. The paper provides an overview of the existing frameworks for competences, skills and qualifications that sets up a baseline for further research and definition of the skills for emerging data driven digital economy. The paper analyses the general profile of the modern agile data driven companies, their culture and required competences. The paper shares the experience of introducing professional and 21 st Century skills in the bachelor and master courses. The project based learning model is proven to be effective in this cases combining the student initiative and self-organisation given the well defined course objectives and reporting requirements.