E-viri
Recenzirano
-
Waring, Michael J.
Bioorganic & medicinal chemistry letters, 05/2009, Letnik: 19, Številka: 10Journal Article
Analysis of a large, structurally diverse Caco-2 permeability dataset using a variety of statistical techniques suggests that log D and molecular weight are the most important factors in determining the permeability of drug candidates. The limit for log D is shown to be dependent on molecular weight. These limits are shown to be potentially superior to current guidelines in increasing the chances of finding highly permeable compounds. When combined with suggested upper limits for lipophilicity suggested in the literature based on the avoidance of toxicology and other adverse effects, this helps define a lipophilicity range that is optimum for drug candidates.
Avtor
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|
Vir: Osebne bibliografije
in: SICRIS
To gradivo vam je dostopno v celotnem besedilu. Če kljub temu želite naročiti gradivo, kliknite gumb Nadaljuj.