Background: Metallic nano-oxide has been influenced the environment in the past two decades. Their consequences are dreadfully uncertain. The increased graph of their interference suggested many extensive studies in various fields of the environment. The Gossypium hirsutum one of the prime harvest plants in India has been chosen for studying the impacts of metallic nano-oxide on their morphological characters as well as their fresh shoot and root weights. Methods: Study has been done in July 2020 as a randomized triplet. The need for the study was fulfilled by the four different metallic nano-oxides with their five specific concentrations. The metallic nano-oxides were titanium oxide, silver oxide, copper oxide and zinc oxide. The five concentrations 00 ppm, 40 ppm, 60 ppm, 80 ppm and 100 ppm were taken from each one of metallic nano-oxide. Result: The zinc oxides treatment gave noteworthy positive growth and development in Gossypium hirsutum from germination to the blossoming time. Conversely, the concentrations of silver oxides were found little toxic for the growth of species. The copper and titanium oxides indicated little diversity in their growth patterns. The germination studies calculated best with titanium oxide treatment. The 80ppm concentration of copper oxide also reported better results at germination in comparison to control.