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de Morais Oliveira-Tintino, Cícera Datiane; Tintino, Saulo Relison; Limaverde, Paulo W.; Figueredo, Fernando G.; Campina, Fábia F.; da Cunha, Francisco A.B.; da Costa, Roger H.S.; Pereira, Pedro Silvino; Lima, Luciene F.; de Matos, Yedda M.L.S.; Coutinho, Henrique Douglas Melo; Siqueira-Júnior, José P.; Balbino, Valdir Q.; da Silva, Teresinha Gonçalves
Food chemistry, 10/2018, Letnik: 262Journal Article
•The essential oil from C. ambrosioides L. leaves potentiated the antibiotic action by inhibition of NorA efflux pumps;•The essential oil from C. ambrosioides L. leaves was innefective against the wild type strain;•The α-Terpinene did not show any activity. This study was carried out to test the essential oil from C. ambrosioides leaves and its main constituent, α-Terpinene, in an antibacterial activity assay. As well, it was evaluated ability reduce resistance to norfloxacin and ethidium bromide was compared the Staphylococcus aureus 1199B whith 1199 wild type strain. The MIC of the C. ambrosioides essential oil and α-Terpinene were determined by microdilution method. The MIC of the essential oil and α-Terpinene presented a value ≥ 1024 μg/mL. However, when associated with antibacterials, the essential oil from C. ambrosioides leaves significantly reduced the MIC of antibiotics and ethidium bromide, characterizing an efflux pump inhibition. The C. ambrosioides essential oil, despite having no direct antibacterial activity against the S. aureus 1199B strain, showed a potentiating action when associated with antibacterial agents, this being attributed to an inhibition of efflux pumps.
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Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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in: SICRIS
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