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Li, Zi‐Yuan; Zhang, Xiao‐Jie; Gao, Yi‐Ming; Song, Yanyan; Sands, Mia X.; Zhou, Shuang‐Bai; Li, Qing‐Feng; Zhang, Junji
Advanced healthcare materials, 07/2023, Letnik: 12, Številka: 17Journal Article
Dressing change is a significant and inevitable process during wound healing. Possible secondary damage caused through dressing removal may impose a great threat on wound recovery, thus resulting in healing delays and ultimately a higher cost of hospitalization. Hence, a non‐contact refreshable dressing with an ease of operation is of great desire, especially for chronic wounds where a long‐term and repeated dressing change would be performed. Herein, an all‐light‐operated hydrogel dressing that would achieve a fast and remote‐controllable dressing change (30 s for gelation/4 min for dissolution upon light irradiation) for chronic wounds is presented. In a diabetic murine model, substantially improved wound healing within 2–3 weeks is observed due to attenuated secondary damage during repeated dressing changes. Moreover, a promising facilitation of the healing processes of epithelialization, collagen deposition, cell proliferation, and inflammatory regulation is also detected, representing a synergistic effect of the photo‐responsive hydrogel dressing for therapeutic efficiency. An in situ on‐demand gelation/dissolution hydrogel dressing is developed for chronic wounds to reduce the secondary damage from repeated dressing changes. The hydrogel dressing enabled fast wound sealing within 30 s and on‐demand dissolution within 4 min, allowing fast and noninvasive dressing application and removal, as well as healing promotion.
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Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Vir: Osebne bibliografije
in: SICRIS
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