E-viri
Recenzirano
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Rödel, Franz; Frey, Benjamin; Multhoff, Gabriele; Gaipl, Udo
Cancer letters, 01/2015, Letnik: 356, Številka: 1Journal Article
Highlights • X-irradiation displays anti-inflammatory activities if applied at low (< 1 Gy) doses. • Pro-inflammatory effects and modulation of anti-tumour immune responses dominate at doses >2 Gy. • Immune modulatory effects originate from nuclear damage and non-(DNA) targeted mechanisms. • Abscopal effects of local X-irradiation are mediated by the induction of immunogenic forms of cell death. • HSP70 immunotherapy may increases therapeutic effectiveness of (chemo) radiotherapy.
