By investigating the susceptibility of 110 sorghum varieties, in the conditions of artificial inoculation, to the causer of Fusarium stalk rot, Fusarium moniliforme Sheld., it was established that there were no completely resistant varieties to this parasite. The least infected variety was Dex. Arcola 100 - 3 x Okaw. Yugoslav and Hungarian cultivated varieties showed insignificant differences regarding susceptibility to Fusarium moniliforme Sheld. By applying the scale from 0-5 they were marked from 2.6 to 3.4. According to these data, in the investigated conditions, the threat of Fusarium stalk rot is constantly present. Obtaining the best condition of sorghum plants can be regarded as a preventive measure since more vital plants are less susceptible to Fusarium diseases.