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de la Rosa-Trevín, J.M.; Quintana, A.; del Cano, L.; Zaldívar, A.; Foche, I.; Gutiérrez, J.; Gómez-Blanco, J.; Burguet-Castell, J.; Cuenca-Alba, J.; Abrishami, V.; Vargas, J.; Otón, J.; Sharov, G.; Vilas, J.L.; Navas, J.; Conesa, P.; Kazemi, M.; Marabini, R.; Sorzano, C.O.S.; Carazo, J.M.
Journal of structural biology, July 2016, 2016-07-00, 20160701, 2016-07, Letnik: 195, Številka: 1Journal Article
In the past few years, 3D electron microscopy (3DEM) has undergone a revolution in instrumentation and methodology. One of the central players in this wide-reaching change is the continuous development of image processing software. Here we present Scipion, a software framework for integrating several 3DEM software packages through a workflow-based approach. Scipion allows the execution of reusable, standardized, traceable and reproducible image-processing protocols. These protocols incorporate tools from different programs while providing full interoperability among them. Scipion is an open-source project that can be downloaded from http://scipion.cnb.csic.es.
