E-viri
Recenzirano
Odprti dostop
-
Nelson, Karen E; Weinstock, George M; Highlander, Sarah K; Worley, Kim C; Creasy, Heather Huot; Wortman, Jennifer Russo; Rusch, Douglas B; Mitreva, Makedonka; Sodergren, Erica; Chinwalla, Asif T; Feldgarden, Michael; Gevers, Dirk; Haas, Brian J; Madupu, Ramana; Ward, Doyle V; Birren, Bruce W; Gibbs, Richard A; Methe, Barbara; Petrosino, Joseph F; Strausberg, Robert L; Sutton, Granger G; White, Owen R; Wilson, Richard K; Durkin, Scott; Giglio, Michelle Gwinn; Gujja, Sharvari; Howarth, Clint; Kodira, Chinnappa D; Kyrpides, Nikos; Mehta, Teena; Muzny, Donna M; Pearson, Matthew; Pepin, Kymberlie; Pati, Amrita; Qin, Xiang; Yandava, Chandri; Zeng, Qiandong; Zhang, Lan; Berlin, Aaron M; Chen, Lei; Hepburn, Theresa A; Johnson, Justin; McCorrison, Jamison; Miller, Jason; Minx, Pat; Nusbaum, Chad; Russ, Carsten; Sykes, Sean M; Tomlinson, Chad M; Young, Sarah; Warren, Wesley C; Badger, Jonathan; Crabtree, Jonathan; Markowitz, Victor M; Orvis, Joshua; Cree, Andrew; Ferriera, Steve; Fulton, Lucinda L; Fulton, Robert S; Gillis, Marcus; Hemphill, Lisa D; Joshi, Vandita; Kovar, Christie; Torralba, Manolito; Wetterstrand, Kris A; Abouellleil, Amr; Wollam, Aye M; Buhay, Christian J; Ding, Yan; Dugan, Shannon; FitzGerald, Michael G; Holder, Mike; Hostetler, Jessica; Clifton, Sandra W; Allen-Vercoe, Emma; Earl, Ashlee M; Farmer, Candace N; Liolios, Konstantinos; Surette, Michael G; Xu, Qiang; Pohl, Craig; Wilczek-Boney, Katarzyna; Zhu, Dianhui
Science, 05/2010, Letnik: 328, Številka: 5981Journal Article
The human microbiome refers to the community of microorganisms, including prokaryotes, viruses, and microbial eukaryotes, that populate the human body. The National Institutes of Health launched an initiative that focuses on describing the diversity of microbial species that are associated with health and disease. The first phase of this initiative includes the sequencing of hundreds of microbial reference genomes, coupled to metagenomic sequencing from multiple body sites. Here we present results from an initial reference genome sequencing of 178 microbial genomes. From 547,968 predicted polypeptides that correspond to the gene complement of these strains, previously unidentified ("novel") polypeptides that had both unmasked sequence length greater than 100 amino acids and no BLASTP match to any nonreference entry in the nonredundant subset were defined. This analysis resulted in a set of 30,867 polypeptides, of which 29,987 (̃97%) were unique. In addition, this set of microbial genomes allows for ̃40% of random sequences from the microbiome of the gastrointestinal tract to be associated with organisms based on the match criteria used. Insights into pan-genome analysis suggest that we are still far from saturating microbial species genetic data sets. In addition, the associated metrics and standards used by our group for quality assurance are presented.
Avtor
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|
Vir: Osebne bibliografije
in: SICRIS
To gradivo vam je dostopno v celotnem besedilu. Če kljub temu želite naročiti gradivo, kliknite gumb Nadaljuj.